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2.3.1.230: 2-heptyl-4(1H)-quinolone synthase

This is an abbreviated version!
For detailed information about 2-heptyl-4(1H)-quinolone synthase, go to the full flat file.

Word Map on EC 2.3.1.230

Reaction

1-(2-aminophenyl)decane-1,3-dione
=
2-heptyl-4-quinolone
+
H2O

Synonyms

2,4-dihydroxyquinoline synthase, PqsBC, PqsD, PsqD

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.230 2-heptyl-4(1H)-quinolone synthase

IC50 Value

IC50 Value on EC 2.3.1.230 - 2-heptyl-4(1H)-quinolone synthase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3.2
(2-nitrophenyl)(phenyl)methanol
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0059
(2-nitrophenyl)(thiophen-3-yl)methanol
Pseudomonas aeruginosa
pH not specified in the publication, temperature not specified in the publication
7.9
(2R)-2,4-dihydroxy-N-(3-[[4-hydroxy-4-(2-nitrophenyl)butyl]amino]-3-oxopropyl)-3,3-dimethylbutanamide
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0032
(S)-(2-nitrophenyl)(phenyl)methanol
Pseudomonas aeruginosa
pH not specified in the publication, temperature not specified in the publication
0.0011
1-(2-nitrophenyl)propan-1-ol
Pseudomonas aeruginosa
pH not specified in the publication, temperature not specified in the publication
4.3
1-[methoxy(phenyl)methyl]-2-nitrobenzene
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.065
2-(4-bromo-3-diethylsulfamoylbenzoylamino)benzoate
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0165
2-([3-[benzyl(ethyl)sulfamoyl]benzoyl]amino)benzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.039
2-chloro-6-[[3-(diethylsulfamoyl)benzoyl]amino]benzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
14.8
2-nitrophenyl phenyl sulfone
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.035
2-[(2-phenoxybiphenyl-4-carbonyl)amino]benzoate
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.044
2-[(3-sulfamoylbenzoyl)amino]benzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0148
2-[[3-(azepan-1-ylsulfonyl)benzoyl]amino]benzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0273
2-[[3-(diethylsulfamoyl)-4-methylbenzoyl]amino]benzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.008
2-[[3-(diethylsulfamoyl)benzoyl]amino]-4-fluorobenzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0063
2-[[3-(diethylsulfamoyl)benzoyl]amino]-4-nitrobenzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0124
2-[[3-(diethylsulfamoyl)benzoyl]amino]-5-(trifluoromethyl)benzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0114
2-[[3-(diethylsulfamoyl)benzoyl]amino]-5-fluorobenzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0184
2-[[3-(diethylsulfamoyl)benzoyl]amino]-5-methylbenzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0089
2-[[3-(diethylsulfamoyl)benzoyl]amino]-5-nitrobenzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.025
2-[[3-(diethylsulfamoyl)benzoyl]amino]-6-fluorobenzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0012
2-[[3-(diethylsulfamoyl)benzoyl]amino]-6-hydroxybenzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0198
2-[[3-(diethylsulfamoyl)benzoyl]amino]benzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0054
2-[[3-(dipropylsulfamoyl)benzoyl]amino]benzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0144
2-[[3-(piperidin-1-ylsulfonyl)benzoyl]amino]benzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0066
2-[[4-bromo-3-(diethylsulfamoyl)benzoyl]amino]-5-fluorobenzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0069
2-[[4-bromo-3-(diethylsulfamoyl)benzoyl]amino]benzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0038
3'-carbamoyl-4-[[3-(diethylsulfamoyl)benzoyl]amino]biphenyl-3-carboxylic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.023
3-(3,4-dihydroxyphenyl)-N-methylpropanamide
Pseudomonas aeruginosa
pH not specified in the publication, temperature not specified in the publication
0.0019
4'-carbamoyl-4-[[3-(diethylsulfamoyl)benzoyl]amino]biphenyl-3-carboxylic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0094
4-chloro-2-[[3-(diethylsulfamoyl)benzoyl]amino]benzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0015
4-[[3-(diethylsulfamoyl)benzoyl]amino]biphenyl-3,3'-dicarboxylic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0027
4-[[3-(diethylsulfamoyl)benzoyl]amino]biphenyl-3,4'-dicarboxylic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.003
4-[[3-(diethylsulfamoyl)benzoyl]amino]biphenyl-3-carboxylic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0255
5-bromo-2-[[3-(diethylcarbamoyl)benzoyl]amino]benzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.009
5-bromo-2-[[3-(diethylsulfamoyl)benzoyl]amino]benzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.013
5-bromo-2-[[4-(diethylsulfamoyl)benzoyl]amino]benzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0038
5-bromo-2-[[4-bromo-3-(diethylsulfamoyl)benzoyl]amino]benzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.026
5-cyano-2-[[3-(diethylsulfamoyl)benzoyl]amino]benzoic acid
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
0.0059
benzyl 3-(3,4-dihydroxyphenyl)propanoate
Pseudomonas aeruginosa
pH not specified in the publication, temperature not specified in the publication
0.02
methyl 3-(3,4-dihydroxyphenyl)propanoate
Pseudomonas aeruginosa
pH not specified in the publication, temperature not specified in the publication
0.0062
N-(2-chloro-6-methylphenyl)biphenyl-4-carboxamide
Pseudomonas aeruginosa
pH not specified in the publication, temperature not specified in the publication
6.2
N-[2-[hydroxy(2-nitrophenyl)methyl]phenyl]acetamide
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
9
N-[3-[hydroxy(2-nitrophenyl)methyl]phenyl]acetamide
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
7.8
N-[4-(2-nitrophenyl)-4-oxobutyl]acetamide
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
4.3
N-[4-hydroxy-4-(2-nitrophenyl)butyl]acetamide
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication
6.4
N-[4-[hydroxy(2-nitrophenyl)methyl]phenyl]acetamide
Pseudomonas aeruginosa
-
pH and temperature not specified in the publication