2.3.1.230: 2-heptyl-4(1H)-quinolone synthase

This is an abbreviated version!
For detailed information about 2-heptyl-4(1H)-quinolone synthase, go to the full flat file.

2,4-dihydroxyquinoline synthase, PqsBC, PqsD, PsqD

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
4	AA Sequence
2	Application
6	Cloned(Commentary)
3	Crystallization (Commentary)
6	General Information
47	IC50 Value
57	Inhibitors
2	kcat/KM [mM/s]
7	KM Value [mM]
3	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
15	Organism
4	Pathway
2	pH Optimum
12	Protein Variants
6	Purification (Commentary)
4	Reaction
15	Reference
1	Specific Activity [micromol/min/mg]
20	Substrates and Products (Substrate)
3	Subunits
8	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
2	Turnover Number [1/s]

Reaction on EC 2.3.1.230 - 2-heptyl-4(1H)-quinolone synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

1-(2-aminophenyl)decane-1,3-dione = 2-heptyl-4-quinolone + H2O

(1c)

octanoyl-CoA + (2-aminobenzoyl)acetate = 2-heptyl-4-quinolone + CoA + CO2 + H2O

overall reaction

octanoyl-CoA + L-cysteinyl-[PqsC protein] = S-octanoyl-L-cysteinyl-[PqsC protein] + CoA

(1a)

S-octanoyl-L-cysteinyl-[PqsC protein] + (2-aminobenzoyl)acetate = 1-(2-aminophenyl)decane-1,3-dione + CO2 + L-cysteinyl-[PqsC protein]

(1b)