2.3.1.236: 5-methylnaphthoic acid synthase

This is an abbreviated version!
For detailed information about 5-methylnaphthoic acid synthase, go to the full flat file.

Reaction

+ 5 malonyl-CoA + 3 NADPH + 3 H+ =

+ 6 CoA + 5 CO2 + 4 H2O + 3 NADP⁺

Synonyms

5-methyl-naphthoic acid synthase, AziB, NPA synthase

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.236 5-methylnaphthoic acid synthase

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Results	in table
3	AA Sequence
2	Cloned(Commentary)
1	General Information
1	Natural Substrates/ Products (Substrates)
3	Organism
1	Protein Variants
1	Reaction
3	Reference
4	Substrates and Products (Substrate)
6	Synonyms
1	Systematic Name

Reference

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Reference on EC 2.3.1.236 - 5-methylnaphthoic acid synthase

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729575

Zhao, Q.; He, Q.; Ding, W.; Tang, M.; Kang, Q.; Yu, Y.; Deng, W.; Zhang, Q.; Fang, J.; Tang, G.; Liu, W.

Characterization of the azinomycin B biosynthetic gene cluster revealing a different iterative type I polyketide synthase for naphthoate biosynthesis

Chem. Biol.

693-705

2008

Streptomyces sahachiroi (B4XYB8)

18635006

735692

Mori, S.; Simkhada, D.; Zhang, H.; Erb, M.S.; Zhang, Y.; Williams, H.; Fedoseyenko, D.; Russell, W.K.; Kim, D.; Fleer, N.; Ealick, S.E.; Watanabe, C.M.

Polyketide ring expansion mediated by a thioesterase, chain elongation and cyclization domain, in azinomycin biosynthesis: characterization of AziB and AziG

Biochemistry

704-714

2016

Streptomyces sahachiroi (B4XYB8), Streptomyces sahachiroi NRRL 2485 (B4XYB8)

26731610