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2.3.1.244: 2-methylbutanoate polyketide synthase

This is an abbreviated version!
For detailed information about 2-methylbutanoate polyketide synthase, go to the full flat file.

Reaction

2 malonyl-CoA +

[2-methylbutanoate polyketide synthase]
+ 2 NADPH + 3 H+ +
S-adenosyl-L-methionine
=
(S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase]
+ 2 CoA + 2 CO2 + 2 NADP+ +
S-adenosyl-L-homocysteine
+
H2O

Synonyms

LDKS, LocF, lovastatin diketide synthase, LovF

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.244 2-methylbutanoate polyketide synthase

Sequence

Sequence on EC 2.3.1.244 - 2-methylbutanoate polyketide synthase

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
LOVF_ASPTE
2532
0
276641
Swiss-Prot
other Location (Reliability: 2)
LOVF_ASPTN
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
2452
0
268120
Swiss-Prot
other Location (Reliability: 2)
MLCB_PENCI
2563
0
280159
Swiss-Prot
Secretory Pathway (Reliability: 5)
MOKB_MONPI
2547
0
278173
Swiss-Prot
other Location (Reliability: 3)