2.3.1.251: lipid IVA palmitoyltransferase
This is an abbreviated version!
For detailed information about lipid IVA palmitoyltransferase, go to the full flat file.
Word Map on EC 2.3.1.251
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2.3.1.251
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palmitoylated
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lipopolysaccharide
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typhimurium
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toll-like
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palmitate
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3-o-deacylase
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two-component
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tlr4-signaling
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phospholipids
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interior
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ruler
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leaflet
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phopq
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deacylase
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aeruginosa
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synthesis
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medicine
- 2.3.1.251
-
palmitoylated
- lipopolysaccharide
- typhimurium
-
toll-like
- palmitate
-
3-o-deacylase
-
two-component
-
tlr4-signaling
- phospholipids
-
interior
-
ruler
- leaflet
-
phopq
-
deacylase
- aeruginosa
- synthesis
- medicine
Reaction
Synonyms
crcA, lipid A palmitoyltransferase, PA1343, PagP
ECTree
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General Information
General Information on EC 2.3.1.251 - lipid IVA palmitoyltransferase
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physiological function
lipid A of a PagP mutant differs from wild-type lipid A by the absence of a palmitate group in secondary acylation at the C3' position. PagP mediates modification of the lipid A as part of the overall Bvg-mediated adaptation of this organism to changing environmental conditions. PagP is not required for the initial colonization of the mouse respiratory tract by Bordetella bronchiseptica, but is required for persistence of the organism within this organ
physiological function
mutation of PagP results in a mutant strain with increased sensitivity to antimicrobial peptide killing and decreased endotoxicity
physiological function
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lipid A of a PagP mutant differs from wild-type lipid A by the absence of a palmitate group in secondary acylation at the C3' position. PagP mediates modification of the lipid A as part of the overall Bvg-mediated adaptation of this organism to changing environmental conditions. PagP is not required for the initial colonization of the mouse respiratory tract by Bordetella bronchiseptica, but is required for persistence of the organism within this organ
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