2.3.1.3: glucosamine N-acetyltransferase

This is an abbreviated version!
For detailed information about glucosamine N-acetyltransferase, go to the full flat file.

Reaction

Synonyms

acetyltransferase, glucosamine, GCN5-related glucosamine N-acetyltransferase, glucosamine acetylase, NAG

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.3 glucosamine N-acetyltransferase

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Results	in table
3	AA Sequence
1	CAS Registry Number
1	Cloned(Commentary)
2	Crystallization (Commentary)
13	Inhibitors
2	kcat/KM [mM/s]
4	KM Value [mM]
1	Localization
1	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
4	Organism
2	Pathway
2	PDB ID
3	Protein Variants
1	Purification (Commentary)
1	Reaction
1	Reaction Type
4	Reference
1	Source Tissue
12	Substrates and Products (Substrate)
1	Subunits
4	Synonyms
1	Systematic Name
1	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 2.3.1.3 - glucosamine N-acetyltransferase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

acetyl-CoA + chitobiose

CoA + N,N'-diacetylchitobiose + N-acetyl-D-glucosamine

Rhizomucor miehei

-

77.5% activity compared to D-glucosamine

737255

-

-

?

acetyl-CoA + chitopentaose

?

Rhizomucor miehei

-

4.7% activity compared to D-glucosamine

737255

-

-

?

acetyl-CoA + chitotetraose

?

Rhizomucor miehei

-

9.3% activity compared to D-glucosamine

737255

-

-

?

acetyl-CoA + chitotriose

?

Rhizomucor miehei

-

12% activity compared to D-glucosamine

737255

-

-

?

acetyl-CoA + D-glucosamine

CoA + N-acetyl-D-glucosamine

6 entries

acetyl-CoA + galactosamine

CoA + N-acetyl-D-galactosamine

Pigeon

-

-

486750

-

-

?

additional information

?

-

Clostridium acetobutylicum

-

GlmA follows an ordered mechanism with acetyl CoA binding first followed by glucosamine. The product N-acetylglucosamine is then released prior to CoA

756038

-

-

-

acetyl-CoA + D-glucosamine

CoA + N-acetyl-D-glucosamine

Avena sativa

-

-

486751

-

486751

?

acetyl-CoA + D-glucosamine

CoA + N-acetyl-D-glucosamine

Avena sativa

-

the first enzyme in the metabolism of D-glucosamine

486751

-

486751

?

acetyl-CoA + D-glucosamine

CoA + N-acetyl-D-glucosamine

Clostridium acetobutylicum

-

-

756038

-

-

?

acetyl-CoA + D-glucosamine

CoA + N-acetyl-D-glucosamine

Pigeon

-

-

486750

-

486750

?

acetyl-CoA + D-glucosamine

CoA + N-acetyl-D-glucosamine

Rhizomucor miehei

-

-

737255

-

-

?

acetyl-CoA + D-glucosamine

CoA + N-acetyl-D-glucosamine

Rhizomucor miehei

-

100% activity

737255

-

-

?