Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.3.1.32: lysine N-acetyltransferase

This is an abbreviated version!
For detailed information about lysine N-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.32

Reaction

acetyl phosphate
+
L-lysine
=
phosphate
 +
N6-acetyl-L-lysine

Synonyms

acetyltransferase p300, acetyltransferase, lysine, ATase1, ATase2, Cbp, cyclic adenosine monophosphate response element-binding binding protein, Esa1, Gcn5, GCN5-A, GCN5-related N-acetyltransferase, GNAT, H4 lysine acetyltransferase, HAT, histone/protein lysine acetyltransferase, KAT, lysine acetyltransferase, NuA4, p/CAF, p300, p300 acetyltransferase, p300/CBP, PCAF, Rtt109 histone acetyltransferase, SePat

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.32 lysine N-acetyltransferase

Cloned

Cloned on EC 2.3.1.32 - lysine N-acetyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed as a His-tagged fusion protein
-
nuclear enzyme overexpression in HEK-293 cells
-
PCR-amplification, stable transfection of CHO cells, with myc-tag, overexpressing enzyme
recombinant p300 is expressed in baculovirus, and K1358A HAT mutant gene is expressed in Escherichia coli BL21
-
recombinant PCAF expressed in baculovirus
-
transfection of COS-1 cells (African green monkey cell line) with plasmids of wild-type enzyme, deficient enzyme or single site mutants fused to reporter genes
-