Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.3.1.32: lysine N-acetyltransferase

This is an abbreviated version!
For detailed information about lysine N-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.32

Reaction

acetyl phosphate
+
L-lysine
=
phosphate
+
N6-acetyl-L-lysine

Synonyms

acetyltransferase p300, acetyltransferase, lysine, ATase1, ATase2, Cbp, cyclic adenosine monophosphate response element-binding binding protein, Esa1, Gcn5, GCN5-A, GCN5-related N-acetyltransferase, GNAT, H4 lysine acetyltransferase, HAT, histone/protein lysine acetyltransferase, KAT, lysine acetyltransferase, NuA4, p/CAF, p300, p300 acetyltransferase, p300/CBP, PCAF, Rtt109 histone acetyltransferase, SePat

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.32 lysine N-acetyltransferase

Substrates Products

Substrates Products on EC 2.3.1.32 - lysine N-acetyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
acetyl phosphate + L-lysine
phosphate + N6-acetyl-L-lysine
show the reaction diagram
-
-
-
?
acetyl phosphate + L-ornithine
phosphate + N5-acetyl-L-ornithine
show the reaction diagram
-
best substrate
-
?
acetyl-CoA + beta-site amyloid precursor protein-cleaving enzyme 1
CoA + acetylated beta-site amyloid precursor protein-cleaving enzyme 1
show the reaction diagram
acetyl-CoA + histone
CoA + acetyl-histone
show the reaction diagram
acetyl-CoA + histone H3 N-terminal tail
CoA + acetylated histone H3 N-terminal tail
show the reaction diagram
50 mM Tris-HCl, pH 8.0, 30°C
-
-
?
acetyl-CoA + histone peptide
CoA + acetylated histone peptide
show the reaction diagram
-
-
-
-
r
acetyl-CoA + L-Lys
?
show the reaction diagram
-
-
-
-
?
acetyl-CoA + L-lysine
CoA + N6-acetyl-L-lysine
show the reaction diagram
-
-
-
-
?
Acs (AMP forming) + L-Lys
?
show the reaction diagram
-
-
-
-
?
septin protein + acetyl-CoA
?
show the reaction diagram
-
TAP-tagged septin proteins are cleaved from the magnetic beads during the KAT assay. Multiple sites of acetylation on four of the five yeast mitotic septins, Cdc3, Cdc10, Cdc12 and Shs1 are discovered. In addition to acetylating itself, NuA4 is capable of acetylating Cdc3, Cdc12 and Shs1 in vitro, acetylation on Cdc10 is not detected
-
-
?