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2.3.1.39: [acyl-carrier-protein] S-malonyltransferase

This is an abbreviated version!
For detailed information about [acyl-carrier-protein] S-malonyltransferase, go to the full flat file.

Word Map on EC 2.3.1.39

Reaction

malonyl-CoA
+
an [acyl-carrier protein]
=
CoA
 +
a malonyl-[acyl-carrier protein]

Synonyms

EtMCAT, FabD, FabD2, FAS, fatty acid synthase, HpMCAT, malonyl CoA-ACP malonyltransferase, malonyl CoA-ACP transacylase, malonyl CoA-acyl carrier protein transacylase, malonyl coenzyme A-acyl carrier protein transacylase, malonyl coenzyme A:acyl carrier protein transacylase, malonyl transacylase, malonyl transferase, malonyl-CoA acyl carrier protein transacylase, malonyl-CoA-acyl carrier protein transacylase, malonyl-CoA/ACP transacylase, malonyl-CoA/holo-ACP transacylase, malonyl-CoA: ACP transacylase, malonyl-CoA:ACP transacylase, malonyl-CoA:AcpM transacylase, malonyl-CoA:acyl carrier protein transacylase, malonyl-CoA:acyl-carrier protein transacylase, malonyl-CoA–acyl carrier protein transacylase, malonyl-coenzyme A (CoA)/holo-ACP transacylase, malonyl-coenzyme A-holo-acyl-carrier protein transacylase, malonyl-coenzyme A: acyl-carrier protein transacylase, malonyl-coenzyme A:ACP transacylase, malonyl-coenzymeA:acyl-carrier protein transacylase, malonyltransferase, [acyl-carrier-protein], MAT, MCAMT, MCAT, MCT, MdcH, More, mtFabD, SaMCAT, SpnMCAT, XoMCAT, [acyl carrier protein]malonyltransferase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.39 [acyl-carrier-protein] S-malonyltransferase

Molecular Weight

Molecular Weight on EC 2.3.1.39 - [acyl-carrier-protein] S-malonyltransferase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
13000
malonate decarboxylase holoenzyme is a heteropentamer, the active form: 1 * 60000, alpha-subunit, plus 1 * 33000, beta-subunit, plus 1 * 28000, gamma subunit, plus 1 * 13000, delta-subunit, plus 1 * 30000, epsilon-subunit. The epsilon subunit functions as malonyl-CoA:ACP transacylase
130000
gel filtration, inactive form of malonate decarboxylase
165000
gel filtration, active form of malonate decarboxylase
27000
28000
malonate decarboxylase holoenzyme is a heteropentamer, the active form: 1 * 60000, alpha-subunit, plus 1 * 33000, beta-subunit, plus 1 * 28000, gamma subunit, plus 1 * 13000, delta-subunit, plus 1 * 30000, epsilon-subunit. The epsilon subunit functions as malonyl-CoA:ACP transacylase
30000
30700
-
calculated from amino acid sequence, consistent with the observed molecular mass of approximately 33000 Da for the enzyme containing the 6-His N-terminal extension
31000
-
HPLC gel filtration
32300
-
from amino acid sequence
33000
malonate decarboxylase holoenzyme is a heteropentamer, the active form: 1 * 60000, alpha-subunit, plus 1 * 33000, beta-subunit, plus 1 * 28000, gamma subunit, plus 1 * 13000, delta-subunit, plus 1 * 30000, epsilon-subunit. The epsilon subunit functions as malonyl-CoA:ACP transacylase
34110
-
electrospray mass spectrometry, hexahistidine-tagged fusion protein
35000
35500
-
1 * 35000, SDS-PAGE, alkylated: 1 * 35500, SDS-PAGE, native: 1 * 36500, SDS-PAGE
36000
-
HPLC gel filtration
36500
-
1 * 35000, SDS-PAGE, alkylated: 1 * 35500, SDS-PAGE, native: 1 * 36500, SDS-PAGE
36660
-
carboxymethylated enzyme: sedimentation equilibrium centrifugation
37000
-
gel filtration
38800
-
calculated from cDNA
40500
-
gel filtration, elution from Sephadex G-100
41500
x * 68000, recombinant GST-tagged enzyme, SDS-PAGE, x * 41500, about, sequence calculation
42000
-
mutant proteins R606A and R606K, Western analysis
43000
-
HPLC-gel permeation chromatography, 2 isozymic forms HPLC analysis
60000
malonate decarboxylase holoenzyme is a heteropentamer, the active form: 1 * 60000, alpha-subunit, plus 1 * 33000, beta-subunit, plus 1 * 28000, gamma subunit, plus 1 * 13000, delta-subunit, plus 1 * 30000, epsilon-subunit. The epsilon subunit functions as malonyl-CoA:ACP transacylase
68000
x * 68000, recombinant GST-tagged enzyme, SDS-PAGE, x * 41500, about, sequence calculation