2.3.1.39: [acyl-carrier-protein] S-malonyltransferase

This is an abbreviated version!
For detailed information about [acyl-carrier-protein] S-malonyltransferase, go to the full flat file.

Word Map on EC 2.3.1.39

2.3.1.39

fas

carboxylase

sterol

triglyceride

lipogenesis

acetyl-coa

adipose

lipogenic

peroxisome

cholesterol

obesity

proliferator-activated

adipocytes

element-binding

lipoprotein

carnitine

lipase

high-fat

steatosis

hepatocytes

srebp-1c

stearoyl-coa

obese

diet-induced

protein-1c

triacylglycerols

palmitate

amp-activated

leptin

anti-obesity

cerulenin

preadipocytes

nafld

adiponectin

palmitoylation

nonalcoholic

malic

lipolysis

hormone-sensitive

srebps

desaturase-1

hfd-induced

orlistat

enoyl

atp-citrate

acyl-acps

acaca

medicine

diagnostics

drug development

palmitoyltransferase-1

biotechnology

chrebp

anti-adipogenic

synthesis

Reaction

Synonyms

EtMCAT, FabD, FabD2, FAS, fatty acid synthase, HpMCAT, malonyl CoA-ACP malonyltransferase, malonyl CoA-ACP transacylase, malonyl CoA-acyl carrier protein transacylase, malonyl coenzyme A-acyl carrier protein transacylase, malonyl coenzyme A:acyl carrier protein transacylase, malonyl transacylase, malonyl transferase, malonyl-CoA acyl carrier protein transacylase, malonyl-CoA-acyl carrier protein transacylase, malonyl-CoA/ACP transacylase, malonyl-CoA/holo-ACP transacylase, malonyl-CoA: ACP transacylase, malonyl-CoA:ACP transacylase, malonyl-CoA:AcpM transacylase, malonyl-CoA:acyl carrier protein transacylase, malonyl-CoA:acyl-carrier protein transacylase, malonyl-CoA�acyl carrier protein transacylase, malonyl-coenzyme A (CoA)/holo-ACP transacylase, malonyl-coenzyme A-holo-acyl-carrier protein transacylase, malonyl-coenzyme A: acyl-carrier protein transacylase, malonyl-coenzyme A:ACP transacylase, malonyl-coenzymeA:acyl-carrier protein transacylase, malonyltransferase, [acyl-carrier-protein], MAT, MCAMT, MCAT, MCT, MdcH, More, mtFabD, SaMCAT, SpnMCAT, XoMCAT, [acyl carrier protein]malonyltransferase

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.39 [acyl-carrier-protein] S-malonyltransferase

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Results	in table
3	Activating Compound
39861	AA Sequence
5	Application
1	CAS Registry Number
37	Cloned(Commentary)
13	Crystallization (Commentary)
4263	Disease/ Diagnostics
4	Expression
20	General Information
8	General Stability
1	IC50 Value
59	Inhibitors
5	kcat/KM [mM/s]
6	Ki Value [mM]
78	KM Value [mM]
13	Localization
34	Molecular Weight [Da]
29	Natural Substrates/ Products (Substrates)
111	Organism
11	Pathway
94	PDB ID
26	pH Optimum
3	pH Range
1	pH Stability
1	pI Value
1	Posttranslational Modification
52	Protein Variants
31	Purification (Commentary)
15	Reaction
1	Reaction Type
85	Reference
2	Renatured (Commentary)
20	Source Tissue
46	Specific Activity [micromol/min/mg]
6	Storage Stability
122	Substrates and Products (Substrate)
13	Subunits
102	Synonyms
1	Systematic Name
20	Temperature Optimum [°C]
11	Temperature Stability [°C]
35	Turnover Number [1/s]

Purification

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Purification on EC 2.3.1.39 - [acyl-carrier-protein] S-malonyltransferase

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5 entries

ammonium sulfate fractionation and column chromatography on DEAE-cellulose

Persea americana

285678

ammonium sulfate fractionation and DEAE-cellulose

2 entries

chromatography on DEAE-cellulose, Sephadex G-100, Sephadex G-75, DEAE-Sephadex, and preparative polyacrylamide gel electrophoresis

Escherichia coli

486882

DEAE-cellulose and DEAE-Sephadex chromatography

Escherichia coli

486864

HiTrap chelating Sepharose column chromatography

Acinetobacter baumannii

V5VFX0

755972

Ni2+-chelate chromatography

Mycobacterium tuberculosis

486892

of 2 isozymes MCT1 and MCT2, using salt fractionation, ion-exchange chromatography, and chromatofocusing

Glycine max

486887

of cytosolic recombinant transacylase, resulting from the expression of DNA corresponding to residues 488-809 of EC 2.3.1.85 in Sf9 cells, purified with column chromatography on DE-53 anion exchanger, high-performance liquid chromatography on an Ultraspherogel SEC3000 and gel filtration

Rattus norvegicus

486896

of the hexahistidine-tagged fusion protein, using Ni(II) affinity chromatography, column chromatography on Q-Sepharose, phenyl Superose and Mono-Q

Streptomyces coelicolor

486891

of the mutants R606A und R606K

partial

purification of the enzyme as a hexahistidine fusion protein

Pseudomonas aeruginosa

486895

recombinant enzyme from Escherichia coli by amylose affinity chromatography and gel filtration

Plasmodium falciparum

661063

recombinant enzyme from strain M15

Escherichia coli K-12

660689

recombinant GST-tagged enzyme from Saccharomyces cereviseae strain INVScl by glutathione affinity chromatoography

Schizochytrium sp.

S4TYX4

737303

recombinant His-tagged enzyme from Escherichia coli strain BL21 by nickel affinity chromatography to homogeneity

Streptomyces coelicolor

663400

recombinant His6-tagged enzyme from Escherichia coli strain BL21 (DE3) by nickel affinity chromatography and gel filtration to over 95% purity

Synechocystis sp.

P73242

735381

recombinant truncated enzyme forms from Sf9 insect cells

Homo sapiens

659451

recombinant wild-type and mutant enzymes from Escherichia coli strain Bl21(DE3)

Streptomyces coelicolor

661061

using Ni-NTA chromatography, ion-exchange chromatography and gel filtration

Mycobacterium tuberculosis

P9WNG5

688366

using streptomycin sulfate, column chromatography on DEAE-cellulose, ammonium sulfate fractionation, chromatography on Sephadex G-100 I column, DEAE-Sephadex column and Sephadex G-100 II column

Escherichia coli

486880