2.3.1.43: phosphatidylcholine-sterol O-acyltransferase
This is an abbreviated version!
For detailed information about phosphatidylcholine-sterol O-acyltransferase, go to the full flat file.
Word Map on EC 2.3.1.43
-
2.3.1.43
-
lipoprotein
-
hdl
-
apolipoproteins
-
cholesteryl
-
high-density
-
triglyceride
-
esterification
-
apoa-i
-
atherosclerosis
-
lipase
-
esterify
-
low-density
-
coronary
-
cardiovascular
-
hdl-cholesterol
-
unesterified
-
opacity
-
apoproteins
-
hypercholesterolemia
-
corneal
-
discoidal
-
atherogenic
-
subfractions
-
hdl-associated
-
triglyceride-rich
-
apoc-iii
-
postheparin
-
synthesis
-
hyperlipoproteinemia
-
lysolecithin
-
vldl-c
-
tg-rich
-
dimyristoyl
-
antiatherogenic
-
b-containing
-
normolipidemic
-
cholesterol-loaded
-
xanthoma
-
medicine
-
lipoprotein-cholesterol
-
chylomicron
-
acyl-coa:cholesterol
-
lipid-free
-
paraoxonase
-
apob-containing
-
hdl-mediated
-
3hcholesterol
-
drug development
-
lipid-poor
-
hypertriglyceridemia
-
tangier
-
very-low-density
-
non-hdl
- 2.3.1.43
- lipoprotein
- hdl
-
apolipoproteins
-
cholesteryl
-
high-density
- triglyceride
- esterification
- apoa-i
- atherosclerosis
- lipase
-
esterify
-
low-density
- coronary
- cardiovascular
-
hdl-cholesterol
-
unesterified
- opacity
- apoproteins
- hypercholesterolemia
- corneal
-
discoidal
-
atherogenic
-
subfractions
-
hdl-associated
-
triglyceride-rich
- apoc-iii
-
postheparin
- synthesis
- hyperlipoproteinemia
- lysolecithin
-
vldl-c
-
tg-rich
-
dimyristoyl
-
antiatherogenic
-
b-containing
-
normolipidemic
-
cholesterol-loaded
-
xanthoma
- medicine
-
lipoprotein-cholesterol
- chylomicron
-
acyl-coa:cholesterol
-
lipid-free
- paraoxonase
-
apob-containing
-
hdl-mediated
-
3hcholesterol
- drug development
-
lipid-poor
- hypertriglyceridemia
- tangier
-
very-low-density
-
non-hdl
Reaction
Synonyms
acyltransferase, lecithin-cholesterol, cholesterol transacyltransferase, LAT, LCAT, lecithin cholesterol acyl transferase, lecithin cholesterol acyltransferase, lecithin-cholesterol acyl transferase, lecithin-cholesterol acyltransferase, lecithin/cholesterol acyltransferase, lecithin: cholesterol acyltransferase, lecithin:cholesterol acyl-transferase, lecithin:cholesterol acyltransferase, lysolecithin acyltransferase, phospholipid-cholesterol acyltransferase, plasma lecithin-cholesterol acyltransferase, TgLCAT, TGME49_272420
ECTree
2.3.1.43 phosphatidylcholine-sterol O-acyltransferaseAdvanced search results
results (
results (KM Value
KM Value on EC 2.3.1.43 - phosphatidylcholine-sterol O-acyltransferase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
KM VALUE [mM] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.00056
1,2-bis[4-(1-pyreno)butanoyl]-sn-glycero-3-phosphocholine
fluorescent assay, pH 7.4, 25°C, recombinant enzyme
0.14
1,2-bis-(1-pyrenebutanoyl)-sn-glycero-3-phosphocholine
-
phospholipase activity
0.19
1,2-bis-(1-pyrenebutanoyl)-sn-glycero-3-phosphocholine
-
phospholipase activity of recombinant enzyme expressed in baby hamster kidney cells
0.55
1,2-bis-(1-pyrenebutanoyl)-sn-glycero-3-phosphocholine
-
phospholipase activity of recombinant enzyme devoid of sialic acid, expressed in baby hamster kidney cells
10.1
1,2-bis-(1-pyrenebutanoyl)-sn-glycero-3-phosphocholine
-
recombinant enzyme expressed in baby hamster kidney cells
20.5
1,2-bis-(1-pyrenebutanoyl)-sn-glycero-3-phosphocholine
-
recombinant enzyme devoid of sialic acid, expressed in baby hamster kidney cells
0.0006
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
-
pH 7.4, 37°C, recombinant wild-type enzyme with mutant A154D/A158D/T161D/A164D apolipoprotein A-I, HDL with a surface charge of -11.3 mV
0.001
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
-
pH 7.4, 37°C, recombinant wild-type enzyme with wild-type apolipoprotein A-I, HDL with a surface charge of -8.2 mV
0.027
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
recombinant enzyme, pH 7.4, 37°C
0.000026
phosphatidylcholine
purified recombinant enzyme, pH 7.5, 37°C
additional information
additional information
-
lysophosphatidylcholine: apparent Km values for LCAT and LAT activities with different apolipoprotein activators
-
additional information
additional information
-
cholesterol: apparent Km values for LCAT and LAT activities with different apolipoprotein activators
-
additional information
additional information
-
apparent Km values for LCAT and LAT activities in presence of cholesterol
-
additional information
additional information
-
apparent Km values for LCAT and LAT activities in presence of lysophosphatidylcholine
-
additional information
additional information
-
Km for two naturally occurring mutant enzymes
-
additional information
additional information
Michaelis-Menten kinetics
-
additional information
additional information
-
kinetics in presence of wild-type apolipoprotein A-I and different mutants of apolipoprotein A-I
-
