2.3.1.44: N-acetylneuraminate 4-O-acetyltransferase
This is an abbreviated version!
For detailed information about N-acetylneuraminate 4-O-acetyltransferase, go to the full flat file.
Word Map on EC 2.3.1.44
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2.3.1.44
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sialic
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9-o-acetylated
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thin-layer
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accoa
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o-acetylesterase
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4-o-acetylation
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sialidase
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ganglioside
- 2.3.1.44
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sialic
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9-o-acetylated
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thin-layer
- accoa
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o-acetylesterase
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4-o-acetylation
- sialidase
- ganglioside
Reaction
Synonyms
acetyltransferase, N-acetylneuraminate 4-O-, sialate O-acetyltransferase
ECTree
2.3.1.44 N-acetylneuraminate 4-O-acetyltransferaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 2.3.1.44 - N-acetylneuraminate 4-O-acetyltransferase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
acetyl-CoA + ganglioside 9-O-acetyl-GD3
CoA + ganglioside 4,9-O-diacetyl-GD3
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110% of the acitivity with ganglioside GD3
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-
?
acetyl-CoA + ganglioside GD1a
CoA + 4-O-acetylganglioside GD1a
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90% of the acitivity with ganglioside GD3
-
-
?
acetyl-CoA + ganglioside GD2
CoA + 4-O-acetylated ganglioside GD2
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48% of the acitivity with ganglioside GD3
-
-
?
acetyl-CoA + ganglioside GQ1b
CoA + 4-O-acetylated ganglioside GQ1b
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125% of the acitivity with ganglioside GD3
-
-
?
acetyl-CoA + ganglioside GT1b
CoA + 4-O-acetylated ganglioside GT1b
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80% of the acitivity with ganglioside GD3
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-
?
acetyl-CoA + N-acetylneuraminate
CoA + N-acetyl-4-O-acetylneuraminate
-
-
-
?
acetyl-CoA + N-acetylneuraminate
CoA + N-acetyl-4-O-acetylneuraminate
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the 4-O-acetyltransferase is specific for the hydroxyl group at C-4 of the pyranose ring of neuraminic acid
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r
acetyl-CoA + N-acetylneuraminate
CoA + N-acetyl-4-O-acetylneuraminate
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the 4-O-acetyl-group seems to be stable, as no conversion of this sialic acid to other O-acetylated species is observed
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r
acetyl-CoA + N-acetylneuraminate
CoA + N-acetyl-4-O-acetylneuraminate
-
-
-
?
acetyl-CoA + N-acetylneuraminate
CoA + N-acetyl-4-O-acetylneuraminate
-
-
-
?
acetyl-CoA + N-acetylneuraminate
CoA + N-acetyl-4-O-acetylneuraminate
-
the 4-O-acetyltransferase is specific for the hydroxyl group at C-4 of the pyranose ring of neuraminic acid
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r
acetyl-CoA + N-acetylneuraminate
CoA + N-acetyl-4-O-acetylneuraminate
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the 4-O-acetyl-group seems to be stable, as no conversion of this sialic acid to other O-acetylated species is observed
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r
acetyl-CoA + N-acetylneuraminate
CoA + N-acetyl-4-O-acetylneuraminate
-
the 4-O-acetyltransferase is specific for the hydroxyl group at C-4 of the pyranose ring of neuraminic acid
-
r
acetyl-CoA + N-acetylneuraminate
CoA + N-acetyl-4-O-acetylneuraminate
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the 4-O-acetyl-group seems to be stable, as no conversion of this sialic acid to other O-acetylated species is observed
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r
