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2.3.1.46: homoserine O-succinyltransferase

This is an abbreviated version!
For detailed information about homoserine O-succinyltransferase, go to the full flat file.

Word Map on EC 2.3.1.46

Reaction

succinyl-CoA
+
L-homoserine
=
CoA
+
O-succinyl-L-homoserine

Synonyms

homoserine O-succinyltransferase, homoserine O-transsuccinylase, homoserine succinyltransferase, homoserine transsuccinylase, homoserine-O-succinyltransferase, HST, HTS, MetA, MetA protein, succinyltransferase, homoserine

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.46 homoserine O-succinyltransferase

Specific Activity

Specific Activity on EC 2.3.1.46 - homoserine O-succinyltransferase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
1100
-
mutant 333 histidine-tagged (S61T/E213V/I229T/N267D/N271K), 50 mM potassium-phosphate buffer, pH 7.5, 40°C, about 50% less active as at 25°C
500
-
wild-type histidine-tagged, 50 mM potassium-phosphate buffer, pH 7.5, 40°C, about 80% less activity as at 25°C
520
-
mutant N267D histidine-tagged, 50 mM potassium-phosphate buffer, pH 7.5, 40°C, almost 5times higher activity at 25°C
610
-
mutant I229T histidine-tagged, 50 mM potassium-phosphate buffer, pH 7.5, 40°C, about 4times higher activity at 25°C
700
-
histidine-tagged enzyme, 50 mM potassium-phosphate buffer, pH 7.5, 40°C, about 3.5times higher activity as at 25°C
additional information