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2.3.1.5: arylamine N-acetyltransferase

This is an abbreviated version!
For detailed information about arylamine N-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.5

Reaction

acetyl-CoA
+
an arylamine
=
CoA
 +
an N-acetylarylamine

Synonyms

(BACAN)NAT3, (MYCAB)NAT1, 2-naphthylamine N-acetyltransferase, 4-aminobiphenyl N-acetyltransferase, ABW01_24350, acetyl CoA-arylamine N-acetyltransferase, acetyltransferase, 2-naphthylamine N-, acetyltransferase, 4-aminobiphenyl, acetyltransferase, arylamine, acetyltransferase, p-aminosalicylate N-, acetyltransferase, procainamide N-, acetyltransferase, serotonin N-, arylamine acetylase, arylamine acetyltransferase, arylamine N-acetyl transferase, arylamine N-acetyltransferase, arylamine N-acetyltransferase 1, arylamine N-acetyltransferase 2, arylamine N-acetyltransferase C, arylamine N-acetyltransferase I, arylamine N-acetyltransferase type 1, arylamine N-acetyltransferase type 2, arylamine N-acetyltransferase type I, arylamine-N-acetyltransferase 1, BanatA, BanatB, BanatC, beta-naphthylamine N-acetyltransferase, indoleamine N-acetyltransferase, MlNAT1, MMNAT, More, MSNAT, N-acetyltransferase, N-acetyltransferase a, N-acetyltransferase b, N-acetyltransferase type 2, N-hydroxyarylamine O-acetyltransferase, NAT, NAT 1, NAT-a, NAT-b, NAT1, NAT2, NAT2*1, NAT2*2, NAT3, NAT31, NfNAT, p-aminosalicylate N-acetyltransferase, PANAT, rhesus NAT2, serotonin acetyltransferase, serotonin N-acetyltransferase, STNAT, TBNAT, Tpau_4046, UDP-2-acetamido-3-amino-2,3-dideoxy-D-glucuronic acid 3-N-acetyltransferase, UDP-D-Glc(2NAc3N)A 3-N-acetyltransferase, WbpD

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.5 arylamine N-acetyltransferase

Cloned

Cloned on EC 2.3.1.5 - arylamine N-acetyltransferase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
2 genes, NAT1 and 2, encoding enzyme proteins, transiently expressed in cultured monkey kidney COS-1 cells
-
a series of constructs is cloned into the pGL3-enhancer
expressed as a His-tagged fusion protein
-
expressed as a His-tagged fusion protein in Escherichia coli
-
expressed in CHO cells
expressed in Escherichia as a His-tagged protein
-
expressed in Escherichia coli
-
expressed in Escherichia coli and in CHO cells
expressed in Escherichia coli as a His-tagged fusion protein
expressed in Escherichia coli BL21 cells
expressed in Escherichia coli BL21(DE3) cells
expressed in Escherichia coli BL21(DE3)CodonPlus-RIL cells
expressed in Escherichia coli JM105 cells
-
expressed in Escherichia coli NEB Express cells
expressed in Escherichia coli Rosetta(DE3)pLysS cells
expression as an N-terminal histidine-tagged protein in Escherichia coli
-
expression in Escherichia coli
expression in HeLa cell
expression of FLAG-tagged wild-type and mutant NAT2 in HEK-293T cells
expression of His-tagged isozyme NAT1 in Escherichia coli strain BL21(DE3)
expression of N-terminally His6-tagged NAT in Escherichia coli strain BL21(DE3)
-
expression of wild-type and mutant NAT1 in Escherichia coli
expression of wild-type and mutant NAT2 in Escherichia coli, the mutant variants are insoluble, inactive enzymes
expresssion in Escherichia coli
for expression in mammalian cells
gene nat encoded in the nat operon, DNA and amio acid sequence determination and analysis, genetic structure, promoter consensus sequences, during in vitro growth all the genes in the putative nat operon are expressed, overview
-
gene NAT1, DNA and amino acid sequence determination and analysis, genetic organization, several splice variants of the NAT1 gene that are expressed from different promoters, expression analysis, the NAT1 gene is located on chromosome 8 at 8p21-22, a region known to be deleted in many human cancers
gene NAT1, DNA and amino acid sequence determnination and analysis, quantitative expression analysis
gene nat3, DNA and amino acid sequence determination and analysis, functional expression of genes nat1, nat2, and nat3 in Escherichia coli strain JM105
gene natA, DNA and amino acid sequence determination and analysis, genetic structure, expression as His-tagged enzyme in Escherichia coli strain BL21(DE3)
gene wbpD, overexpression of the N-terminally His-tagged enzyme in strain CQW40
-
human NAT1 and NAT2 genes located on chromosome 8p22
-
human wild-type NAT2 is overexpressed as a dihydrofolate reductase fusion protein containing a TEV protease-sensitive linker
-
into the pET28a vector for expression in Escherichia coli BL21DE3 cells
into the pET28a vector for expression in Escherichia coli BL21DE3 pLysS cells
into the pET28a vector for expression in Escherichia coli cells
-
into the pET28a+ vector for expression in Escherichia coli BL21DE3 cells
-
into the pET28b+ vector for expression in Escherichia coli BL21DE3 pLysS cells
-
into the pKK223-3 bacterial expression vector for transformation of Escherichia coli JM105 cells
isozyme NAT1
-
isozyme NAT2, DNA and amino acid sequence determination and analysis, expression of wild-type and mutants in Escherichia coli strain JM105
isozyme NAT2, expression in Escherichia coli strain DJ2002
liver cDNA clones introduced in Chinese hamster ovary cells
-
NAT1 and NAT2, expressed in Escherichia coli XA90
-
NAT1 is recombinantly expressed
-
NAT1, DNA and amino acid sequence determination and analysis, exon composition, expression analysis, identification of an alternative NAT1 promoter lying 51.5 kb upstream of the NAT1 ORF, all NAT1 P3 mRNAs included 5'-untranslated region internal exons of 61 and 175 nucleotides in addition to the 79 nucleotide 5'-untranslated region exon present in P1 mRNA CAP-dependent amplification of 50-P3 mRNA termini defined an 84 base pair transcription start region in which most start sites are centrally clustered, overview
-
over-expressed in Salmonella typhimurium umu strain
-
overexpression in Escherichia coli
-
the open-reading frame of the gene for Mycobacterium smegmatis N-acetyltransferase plus an N-terminal hexa-histidine tag is expressed in Escherichia coli BL21DE3-pLysS cells
-
tissue-specific expression analysis of isozyme NAT1
tissue-specific expression analysis of isozyme NAT2