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2.3.1.5: arylamine N-acetyltransferase

This is an abbreviated version!
For detailed information about arylamine N-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.5

Reaction

acetyl-CoA
+
an arylamine
=
CoA
 +
an N-acetylarylamine

Synonyms

(BACAN)NAT3, (MYCAB)NAT1, 2-naphthylamine N-acetyltransferase, 4-aminobiphenyl N-acetyltransferase, ABW01_24350, acetyl CoA-arylamine N-acetyltransferase, acetyltransferase, 2-naphthylamine N-, acetyltransferase, 4-aminobiphenyl, acetyltransferase, arylamine, acetyltransferase, p-aminosalicylate N-, acetyltransferase, procainamide N-, acetyltransferase, serotonin N-, arylamine acetylase, arylamine acetyltransferase, arylamine N-acetyl transferase, arylamine N-acetyltransferase, arylamine N-acetyltransferase 1, arylamine N-acetyltransferase 2, arylamine N-acetyltransferase C, arylamine N-acetyltransferase I, arylamine N-acetyltransferase type 1, arylamine N-acetyltransferase type 2, arylamine N-acetyltransferase type I, arylamine-N-acetyltransferase 1, BanatA, BanatB, BanatC, beta-naphthylamine N-acetyltransferase, indoleamine N-acetyltransferase, MlNAT1, MMNAT, More, MSNAT, N-acetyltransferase, N-acetyltransferase a, N-acetyltransferase b, N-acetyltransferase type 2, N-hydroxyarylamine O-acetyltransferase, NAT, NAT 1, NAT-a, NAT-b, NAT1, NAT2, NAT2*1, NAT2*2, NAT3, NAT31, NfNAT, p-aminosalicylate N-acetyltransferase, PANAT, rhesus NAT2, serotonin acetyltransferase, serotonin N-acetyltransferase, STNAT, TBNAT, Tpau_4046, UDP-2-acetamido-3-amino-2,3-dideoxy-D-glucuronic acid 3-N-acetyltransferase, UDP-D-Glc(2NAc3N)A 3-N-acetyltransferase, WbpD

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.5 arylamine N-acetyltransferase

Storage Stability

Storage Stability on EC 2.3.1.5 - arylamine N-acetyltransferase

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STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-20°C, 50% glycerol
-
-20°C, at least 2 years in the presence of 10% glycerol v/v
-
-60°C, 60-80% loss of activity after 3 weeks
-
-60°C, at least 3 weeks in the presence of 2-mercaptoethanol, thioglycolate or cysteine
-
-70°C, frozen at neutral pH in liquid nitrogen, no loss of activity over a long-time range
-
-70°C, stable for several months
-
4°C, 2 months, no apparent degradation of the enzyme, no change in activity
-
4°C, 20% loss of activity within 4 days in the presence of 1 mM EDTA
-
4°C, purified recombinant enzyme in 50 mM sodium phosphate, pH 7.0, 0.15 M NaCl, and 7.5 mM 2-mercaptoethanol, 2 weeks, stable
4°C, several days in various buffer systems at pH 6.0-8.5
-
frozen, over a long-time range as ammonium sulfate precipitate
-