2.3.1.51: 1-acylglycerol-3-phosphate O-acyltransferase

This is an abbreviated version!
For detailed information about 1-acylglycerol-3-phosphate O-acyltransferase, go to the full flat file.

Reaction

Synonyms

1-acyl-sn-glycero-3-phosphate acyltransferase, 1-acyl-sn-glycero-3-phosphate acyltransferase 1, 1-acyl-sn-glycero-3-phosphate acyltransferase 9, 1-acyl-sn-glycerol 3-phosphate acyltransferase, 1-acyl-sn-glycerol-3-phosphate acyltransferas, 1-acyl-sn-glycerol-3-phosphate acyltransferase, 1-acyl-sn-glycerol-3-phosphate O-acyltransferase, 1-acylglycero-3-phosphate acyltransferase, 1-acylglycerol 3-phosphate O-acyltransferase, 1-acylglycerol-3-phosphate acyltransferase, 1-acylglycerol-3-phosphate-O-acyltransferase, 1-acylglycerol-3-phosphate-O-acyltransferase 2, 1-acylglycerol-3-phosphate-O-acyltransferase isoform10/glycerol-3-phosphate acyltransferase isoform 3, 1-acylglycerol-3-phosphate-O-acyltransferase-1, 1-acylglycerolphosphate acyltransferase, 1-acylglycerophosphate acyltransferase, 1-Agpat2, ABHD5, acyl-CoA: sn-1-acyl-glycerol-3-phosphate acyltransferase, acyl-CoA:1-acylglycerol-sn-3-phosphate acyltransferase, acyl-CoA:lysophosphatidic acid acyltransferase, acyl-CoA:lysophospholipid acyltransferase, acyl-coenzyme A-dependent lysophosphatidic acid acyltransferase, acylglycerophosphate acyltransferase 4, acyltransferase, 1-acylglycerol phosphate, AGPAT, AGPAT/PlsC, AGPAT1, AGPAT10/GPAT3, AGPAT11, AGPAT2, AGPAT3, AGPAT4, AGPAT5, AGPAT6/GPAT4, AGPAT9, ALE1, At4g24160, AtLPAAt2, CGFI-58, cgi-58 protein, CGI-58/ABHD5, CHLREDRAFT_174358, coenzyme A-dependent lysophosphatidic acid, CrLPAAT1, CT775, CT_775, endoplasmic reticulum-located LPAT, ER-located LPAT, glycerol-3-phosphate acyltransferase-1, GPAT-1, ICT1 protein, LOA1, LPA acyltransferase, LPAAT, LPAAT-beta, LPAAT1, LPAAT2, LPAAT3, LPAAT4, LPAATbeta, LPAATdelta, LPAT, LPCAT1, LPCAT2, lysophosphatidic acid acyl transferase, lysophosphatidic acid acyltansferase, lysophosphatidic acid acyltransferase, lysophosphatidic acid acyltransferase 3, lysophosphatidic acid acyltransferase beta, lysophosphatidic acid ayltransferase, lysophosphatidic acid-acyltransferase, lysophosphatidic acid�specific acyltransferase, lysophosphatidyl acyltransferase, lysophosphatidyl acyltransferase 4, lysophosphatidylcholine acyltransferase 1, lysophospholipid acyltransferase, lysophospholipid:acyl-CoA acyltransferase, mAGPAT1, mAGPAT2, mAGPAT3, mAGPAT4, mAGPAT5, More, oleoyl-CoA lysophosphatidic acid acyltransferase, PCC8801_1274, plastidial LPAAT, plastidial lysophosphatidic acid acyltransferase, PlsC, PlsC4, PrLPAAT1, Scl1, ScLPAAT, SLC1, Slc1p, Slc4p, SlPlsC1, SMc00714 protein, SnGlycerol 3-P acyltransferase, TmPlsC, TM_1693, YPR139c

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.51 1-acylglycerol-3-phosphate O-acyltransferase

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Results	in table
4	Activating Compound
23186	AA Sequence
4	Application
1	CAS Registry Number
66	Cloned(Commentary)
1	Crystallization (Commentary)
604	Disease/ Diagnostics
6	Expression
73	General Information
4	General Stability
29	Inhibitors
1	kcat/KM [mM/s]
29	KM Value [mM]
119	Localization
10	Metals/Ions
17	Molecular Weight [Da]
96	Natural Substrates/ Products (Substrates)
484	Organism
19	Pathway
3	PDB ID
48	pH Optimum
4	pH Range
1	pH Stability
2	pI Value
40	Protein Variants
21	Purification (Commentary)
1	Reaction
1	Reaction Type
119	Reference
3	Renatured (Commentary)
207	Source Tissue
16	Specific Activity [micromol/min/mg]
8	Storage Stability
524	Substrates and Products (Substrate)
18	Subunits
272	Synonyms
1	Systematic Name
40	Temperature Optimum [°C]
3	Temperature Range [°C]
5	Temperature Stability [°C]

Expression

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Expression on EC 2.3.1.51 - 1-acylglycerol-3-phosphate O-acyltransferase

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

AGPAT2 expression is increased during adipocyte differentiation and mutations cause congenital generalised lipodystrophy (CGL) type 1

Homo sapiens

O15120, Q99943, Q9NRZ5, Q9NRZ7, Q9NUQ2

756108

expression of isoform AGPAT11 mRNA is significantly upregulated in human breast, cervical, and colorectal cancer tissues

Homo sapiens

Q7L5N7

720175

expression of the enzyme in the testis increases significantly in an age-dependent manner, which is regulated by induction through beta-estradiol, in TM4 cells

2 entries

isoform LPAAT3 is induced during germ cell maturation. Differentiation of mouse GC-2spd(ts) spermatocytes into spermatides up-regulates isoform LPAAT3 mRNA, increases the amount of polyunsaturated phospholipids, and shifts the specificity for the incorporation of docosahexaenoic acid toward phosphatidylcholine and phosphatidylethanolamine

Mus musculus

C4B4E7

719440

the transcript level is constant during coconut endosperm development

Cocos nucifera

Q42670

737242

expression of the enzyme in the testis increases significantly in an age-dependent manner, which is regulated by induction through beta-estradiol, in TM4 cells

Mus musculus

C4B4E7

705005

expression of the enzyme in the testis increases significantly in an age-dependent manner, which is regulated by induction through beta-estradiol, in TM4 cells

Mus musculus C57/BL6J

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