Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
acyl-CoA + 1-acyl-lysophosphatidic acid
CoA + 1,2-diacyl-lysophosphatidic acid
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
acyl-CoA + 1-oleoyl-lysophosphatidic acid
CoA + 1-oleoyl-2-acyl-lysophosphatidic acid
acyl-[acyl-carrier protein] + 1-acyl-sn-glycerol 3-phosphate
ACP + 1,2-diacyl-sn-glycerol 3-phosphate
acyl-[acyl-carrier protein] + 1-acyl-sn-glycerol 3-phosphate
acyl-carrier protein + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
?
arachidonoyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1-acyl-2-arachidonoyl-sn-glycerol 3-phosphate
eicosapentaenoyl-CoA + 1-acyl-lysophosphatidic acid
CoA + 1-acyl-2-eicosapentaenoyl-lysophosphatidic acid
lauroyl-CoA + 1-lauroyl-sn-glycerol 3-phosphate
CoA + 1,2-dilauroyl-sn-glycerol 3-phosphate
-
-
-
?
myristoyl-CoA + 1-myristoyl-sn-glycerol 3-phosphate
CoA + 1,2-dimyristoyl-sn-glycerol 3-phosphate
-
-
-
?
oleoyl-CoA + 1-oleoyl-2-lysophosphatidylinositol
CoA + 1,2-dioleoyl-sn-phosphatidylinositol
-
-
-
-
?
oleoyl-CoA + 1-oleoyl-lysophosphatidic acid
CoA + 1,2-dioleoyl-sn-lysophosphatidic acid
-
-
-
r
oleoyl-CoA + 1-oleoyl-sn-lysophosphatidylethanolamine
CoA + 1,2-dioleoyl-sn-lysophosphatidylethanolamine
-
-
-
r
palmitoyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1-acyl-2-palmitoyl-sn-glycerol 3-phosphate
-
-
-
?
additional information
?
-
acyl-CoA + 1-acyl-lysophosphatidic acid
CoA + 1,2-diacyl-lysophosphatidic acid
-
-
-
?
acyl-CoA + 1-acyl-lysophosphatidic acid
CoA + 1,2-diacyl-lysophosphatidic acid
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
i.e. lysophosphatidic acid
i.e. phosphatidic acid
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
pivotal enzyme controlling the metabolic flow of lysophosphatidic acid into different phosphatidic acids in diverse tissues, enzyme is essential in embryo development
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
i.e. lysophosphatidic acid
i.e. phosphatidic acid
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
involved in phospholipid biosynthesis
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
involved in phospholipid biosynthesis
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
reduction in AGPAT2 activity underlies the loss of adipose tissue in congenital generalized lipodystrophy
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
AGPAT2 catalyzes acylation of lysophosphatidic acid to phosphatidic acid, a precursor for both triacylglycerol and phospholipid synthesis, isozyme AGPAT2 plays a regulatory role in adipocyte differentiation
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
activity and expression pattern of AGPAT9 in lung and spleen implicates role in the biosynthesis of phospholipids and triglycerides in these tissues
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
the enzyme catalyzes the second acylations in the glycerol-3-phosphate pathway
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
C4B4E7
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
i.e. lysophosphatidic acid
i.e. phosphatidic acid
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
the expression of AGPATs is linked to skin barrier requirements
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
the enzyme has high acyl-CoA specificity for polyunsaturated fatty acyl-CoA, especially docosahexaenoyl-CoA
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
C4B4E7
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
KX256278
enzyme LPAAT catalyzes lysophosphatidic acid to yield phosphatidic acid by acylation of the sn-2 position of glycerol 3-phosphate. LPAAT is able to discriminate acyl groups with different chain lengths and possesses a selectivity and specificity for unsaturated C18 acyl groups in traditional oil seed crops
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
involved in phospholipid biosynthesis
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
involved in phospholipid biosynthesis
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
involved in phospholipid biosynthesis
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
involved in phospholipid biosynthesis
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
acyltranferase activity by Slc1p and Slc4p
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
Slc1p and Slc4p both active as acyltransferases, involved in fatty acid exchange of mature glycerophospholipids
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
involved in phospholipid biosynthesis
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + 1-oleoyl-lysophosphatidic acid
CoA + 1-oleoyl-2-acyl-lysophosphatidic acid
-
-
-
?
acyl-CoA + 1-oleoyl-lysophosphatidic acid
CoA + 1-oleoyl-2-acyl-lysophosphatidic acid
-
-
-
?
acyl-CoA + 1-oleoyl-lysophosphatidic acid
CoA + 1-oleoyl-2-acyl-lysophosphatidic acid
-
-
-
?
acyl-CoA + 1-oleoyl-lysophosphatidic acid
CoA + 1-oleoyl-2-acyl-lysophosphatidic acid
-
-
-
?
acyl-CoA + 1-oleoyl-lysophosphatidic acid
CoA + 1-oleoyl-2-acyl-lysophosphatidic acid
-
-
-
?
acyl-CoA + 1-oleoyl-lysophosphatidic acid
CoA + 1-oleoyl-2-acyl-lysophosphatidic acid
-
-
-
-
?
acyl-CoA + 1-oleoyl-lysophosphatidic acid
CoA + 1-oleoyl-2-acyl-lysophosphatidic acid
-
-
-
?
acyl-CoA + 1-oleoyl-lysophosphatidic acid
CoA + 1-oleoyl-2-acyl-lysophosphatidic acid
-
-
-
?
acyl-[acyl-carrier protein] + 1-acyl-sn-glycerol 3-phosphate
ACP + 1,2-diacyl-sn-glycerol 3-phosphate
-
involved in phospholipid biosynthesis in chloroplasts
-
?
acyl-[acyl-carrier protein] + 1-acyl-sn-glycerol 3-phosphate
ACP + 1,2-diacyl-sn-glycerol 3-phosphate
-
involved in phospholipid biosynthesis in chloroplasts
-
?
arachidonoyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1-acyl-2-arachidonoyl-sn-glycerol 3-phosphate
C4B4E7
-
-
-
?
arachidonoyl-CoA + 1-acyl-sn-glycerol 3-phosphate
CoA + 1-acyl-2-arachidonoyl-sn-glycerol 3-phosphate
C4B4E7
-
-
-
?
eicosapentaenoyl-CoA + 1-acyl-lysophosphatidic acid
CoA + 1-acyl-2-eicosapentaenoyl-lysophosphatidic acid
-
-
-
?
eicosapentaenoyl-CoA + 1-acyl-lysophosphatidic acid
CoA + 1-acyl-2-eicosapentaenoyl-lysophosphatidic acid
-
-
-
?
additional information
?
-
the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum
-
-
?
additional information
?
-
the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum
-
-
?
additional information
?
-
the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum
-
-
?
additional information
?
-
the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum
-
-
?
additional information
?
-
the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum
-
-
?
additional information
?
-
-
the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum
-
-
?
additional information
?
-
comparison of the substrate specificities of enzymes from different species, positional analysis of fatty acids in seed oil and tiacylglycerols, overview
-
-
-
additional information
?
-
-
1-palmitoyl- and 1-oleoyl-sn-glycerol 3-phosphate are probably the substrates for the enzyme in vivo, since palmitic and oleic acids are the major fatty acid components at the sn-1 position of cow milk triacylglycerols. The specificity of the enzyme plays a major role in determining the fatty acid composition at the sn-2 position of cow milk triacylglycerols, though the influence of other factors such as the in vivo concentration of the acyl-CoAs and the specificities of the monoacylglycerol acyltransferases cannot be ruled out
-
-
?
additional information
?
-
-
the enzyme controls phosphatidic acid biosynthesis in the plastid
-
-
?
additional information
?
-
comparison of the substrate specificities of enzymes from different species, positional analysis of fatty acids in seed oil and tiacylglycerols, overview
-
-
-
additional information
?
-
the broad substrate specificity of acyltransferase CT775 provides the organism with the capacity to incorporate straight-chain and bacterial specific branched-chain fatty acids. In vivo incorporation of 1-acyl-GPC in cells infected with Chlamydia trachomatis confirms the active remodeling of exogenous lipids that are translocated into the inclusions
-
-
-
additional information
?
-
-
the broad substrate specificity of acyltransferase CT775 provides the organism with the capacity to incorporate straight-chain and bacterial specific branched-chain fatty acids. In vivo incorporation of 1-acyl-GPC in cells infected with Chlamydia trachomatis confirms the active remodeling of exogenous lipids that are translocated into the inclusions
-
-
-
additional information
?
-
the broad substrate specificity of acyltransferase CT775 provides the organism with the capacity to incorporate straight-chain and bacterial specific branched-chain fatty acids. In vivo incorporation of 1-acyl-GPC in cells infected with Chlamydia trachomatis confirms the active remodeling of exogenous lipids that are translocated into the inclusions
-
-
-
additional information
?
-
-
the enzyme has medium chain length substrate specificity appropriate to the biosynthesis of coconut oil
-
-
?
additional information
?
-
comparison of the substrate specificities of enzymes from different species, positional analysis of fatty acids in seed oil and triacylglycerols, overview
-
-
-
additional information
?
-
-
comparison of the substrate specificities of enzymes from different species, positional analysis of fatty acids in seed oil and triacylglycerols, overview
-
-
-
additional information
?
-
-
AGPAT8 shows moderate acyltransferase activity with oleoyl-CoA but lacks acyl-CoA:lysocardiolipin acyltransferase activity, human AGPAT2, acylation at the sn-2 position with wild-type AGPAT8 is similar for the LPA species containing oleoyl, linoleoyl, linolenoyl, and palmitoyl fatty acids at the sn-1 position, LPA species containing myristoyl, arachidoyl, arachidonoyl are not preferred, substrate specificity in vivo, overview
-
-
?
additional information
?
-
-
CGI-58 is a CoA-dependent lysophosphatidic acid acyltransferase that channels fatty acids released from the hydrolysis of stored triacylglycerols into phospholipids, overview
-
-
?
additional information
?
-
-
LPAAT3 regulates Golgi membrane tubule formation, trafficking, and structure by altering phospholipids and lysophospholipids. LPAAT3 alters ERGIC-53 distribution, a p58 receptor which is a lectin receptor that traffics between the cis-Golgi and the endoplasmic reticulum
-
-
?
additional information
?
-
isozymes AGPAT3 and AGPAT5 have weak LPAAT activity compared to isozyme AGPAT2 and utilize other lysophospholipids as substrates
-
-
-
additional information
?
-
isozymes AGPAT3 and AGPAT5 have weak LPAAT activity compared to isozyme AGPAT2 and utilize other lysophospholipids as substrates
-
-
-
additional information
?
-
isozymes AGPAT3 and AGPAT5 have weak LPAAT activity compared to isozyme AGPAT2 and utilize other lysophospholipids as substrates
-
-
-
additional information
?
-
isozymes AGPAT3 and AGPAT5 have weak LPAAT activity compared to isozyme AGPAT2 and utilize other lysophospholipids as substrates
-
-
-
additional information
?
-
isozymes AGPAT3 and AGPAT5 have weak LPAAT activity compared to isozyme AGPAT2 and utilize other lysophospholipids as substrates
-
-
-
additional information
?
-
comparison of the substrate specificities of enzymes from different species, positional analysis of fatty acids in seed oil and tiacylglycerols, overview
-
-
-
additional information
?
-
pLAT2 may be necessary only for specific storage triacylglycerol biosynthesis in developing seed
-
-
?
additional information
?
-
pLAT2 may be necessary only for specific storage triacylglycerol biosynthesis in developing seed
-
-
?
additional information
?
-
LPAT1 may be an enzyme required for membrane phospholipid biosynthesis in all tissues
-
-
?
additional information
?
-
LPAT1 may be an enzyme required for membrane phospholipid biosynthesis in all tissues
-
-
?
additional information
?
-
comparison of the substrate specificities of enzymes from different species, positional analysis of fatty acids in seed oil and tiacylglycerols, overview
-
-
-
additional information
?
-
-
comparison of the substrate specificities of enzymes from different species, positional analysis of fatty acids in seed oil and tiacylglycerols, overview
-
-
-
additional information
?
-
-
CGI-58 is a CoA-dependent lysophosphatidic acid acyltransferase that channels fatty acids released from the hydrolysis of stored triacylglycerols into phospholipids, overview
-
-
?
additional information
?
-
CGI-58 is a CoA-dependent lysophosphatidic acid acyltransferase that channels fatty acids released from the hydrolysis of stored triacylglycerols into phospholipids, overview
-
-
?
additional information
?
-
C4B4E7
mouse LPAAT3, previously known as mouse AGPAT3, possesses strong LPAAT activity and modest lysophosphatidylinositol acyltransferase activity with a clear preference for arachidonoyl-CoA as a donor, overview
-
-
?
additional information
?
-
-
mouse LPAAT3, previously known as mouse AGPAT3, possesses strong LPAAT activity and modest lysophosphatidylinositol acyltransferase activity with a clear preference for arachidonoyl-CoA as a donor, overview
-
-
?
additional information
?
-
C4B4E7
mouse LPAAT3, previously known as mouse AGPAT3, possesses strong LPAAT activity and modest lysophosphatidylinositol acyltransferase activity with a clear preference for arachidonoyl-CoA as a donor, overview
-
-
?
additional information
?
-
-
acyl-ACP rather than acyl-CoA is the physiological acyl donor for glycerolipid biosynthesis in chloroplasts
-
-
?
additional information
?
-
-
acyl-CoA thioesters can be considered as the physiological substrates of the microsomal enzyme
-
-
?
additional information
?
-
analysis of distribution of fatty acids at sn-positions of glycerol moiety of glycerolipids, overview
-
-
-
additional information
?
-
-
analysis of distribution of fatty acids at sn-positions of glycerol moiety of glycerolipids, overview
-
-
-
additional information
?
-
comparison of the substrate specificities of enzymes from different species, positional analysis of fatty acids in seed oil and tiacylglycerols, overview. The yeast LPAAT Slc1p or ScLPAAT has been shown to have activity with 22:1-CoA in addition to 18:1-CoA substrates, indicating a broad substrate specificity with respect to chain length although 22:6-CoA, 22:5-CoA, and other LC-PUFAs has not been tested as substrates
-
-
-
additional information
?
-
-
fatty acid and phospholipid profiles, overview
-
-
?
additional information
?
-
-
acyl-ACP rather than acyl-CoA is the physiological acyl donor for glycerolipid biosynthesis in chloroplasts
-
-
?
additional information
?
-
the enzyme has preference for cyclopropene fatty acids
-
-
?
additional information
?
-
-
the enzyme has preference for cyclopropene fatty acids
-
-
?
additional information
?
-
comparison of the substrate specificities of enzymes from different species, positional analysis of fatty acids in seed oil and tiacylglycerols, overview
-
-
-