2.3.1.52: 2-acylglycerol-3-phosphate O-acyltransferase

This is an abbreviated version!
For detailed information about 2-acylglycerol-3-phosphate O-acyltransferase, go to the full flat file.

Reaction

Synonyms

2-acylglycerophosphate acyltransferase, acyl-CoA:2-monoacyl-sn-glycerol 3-phosphate acyltransferase, acyltransferase, 2-acylglycerol phosphate

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.52 2-acylglycerol-3-phosphate O-acyltransferase

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Results	in table
1	CAS Registry Number
11	Localization
1	Natural Substrates/ Products (Substrates)
13	Organism
2	Pathway
1	Purification (Commentary)
1	Reaction
1	Reaction Type
10	Reference
4	Source Tissue
2	Specific Activity [micromol/min/mg]
1	Storage Stability
22	Substrates and Products (Substrate)
3	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]

Substrates Products

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Substrates Products on EC 2.3.1.52 - 2-acylglycerol-3-phosphate O-acyltransferase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

acyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1,2-diacyl-sn-glycerol 3-phosphate

Tetrahymena pyriformis

-

initial step in glycerophospholipid synthesis

486355

-

-

?

arachidonoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-arachidonoyl-2-acyl-sn-glycerol 3-phosphate

Rattus norvegicus

-

poor acyl donor

486643

-

-

?

lauroyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-lauroyl-2-acyl-sn-glycerol 3-phosphate

Rattus norvegicus

-

poor acyl donor

486643

-

-

?

linoleoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-linoleoyl-2-acyl-sn-glycerol 3-phosphate

Rattus norvegicus

-

poor acyl donor

486643

-

-

?

myristoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-myristoyl-2-acyl-sn-glycerol 3-phosphate

Rattus norvegicus

-

poor acyl donor

486643

-

-

?

oleoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-oleoyl-2-acyl-sn-glycerol 3-phosphate

7 entries

palmitoleoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-palmitoleoyl-2-acyl-sn-glycerol 3-phosphate

Rattus norvegicus

-

poor acyl donor

486643

-

-

?

palmitoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-palmitoyl-2-acyl-sn-glycerol 3-phosphate

7 entries

stearoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-stearoyl-2-acyl-sn-glycerol 3-phosphate

Rattus norvegicus

-

most effective acyl donor

486643

-

-

?

oleoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-oleoyl-2-acyl-sn-glycerol 3-phosphate

Mus musculus

-

preferred substrate

487212

-

-

?

oleoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-oleoyl-2-acyl-sn-glycerol 3-phosphate

Mus musculus C57BL

-

preferred substrate

487212

-

-

?

oleoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-oleoyl-2-acyl-sn-glycerol 3-phosphate

Rattus norvegicus

-

-

487212

-

-

?

oleoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-oleoyl-2-acyl-sn-glycerol 3-phosphate

Rattus norvegicus

-

poor

486643

-

-

?

oleoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-oleoyl-2-acyl-sn-glycerol 3-phosphate

Saccharomyces cerevisiae

-

-

486375

-

-

?

oleoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-oleoyl-2-acyl-sn-glycerol 3-phosphate

Spinacia oleracea

-

-

486337

-

-

?

oleoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-oleoyl-2-acyl-sn-glycerol 3-phosphate

Tetrahymena pyriformis

-

poor

486355

-

-

?

palmitoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-palmitoyl-2-acyl-sn-glycerol 3-phosphate

Mus musculus

-

-

487212

-

-

?

palmitoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-palmitoyl-2-acyl-sn-glycerol 3-phosphate

Mus musculus C57BL

-

-

487212

-

-

?

palmitoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-palmitoyl-2-acyl-sn-glycerol 3-phosphate

Rattus norvegicus

-

preferred substrate

486643, 487212

-

-

?

palmitoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-palmitoyl-2-acyl-sn-glycerol 3-phosphate

Rattus norvegicus

-

predominant selectivity for saturated acyl-CoA thioesters

486643

-

-

?

palmitoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-palmitoyl-2-acyl-sn-glycerol 3-phosphate

Saccharomyces cerevisiae

-

-

486375

-

486375

?

palmitoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-palmitoyl-2-acyl-sn-glycerol 3-phosphate

Spinacia oleracea

-

-

486337

-

-

?

palmitoyl-CoA + 2-acyl-sn-glycerol 3-phosphate

CoA + 1-palmitoyl-2-acyl-sn-glycerol 3-phosphate

Tetrahymena pyriformis

-

-

486355

-

-

?