2.3.1.60: gentamicin 3-N-acetyltransferase
This is an abbreviated version!
For detailed information about gentamicin 3-N-acetyltransferase, go to the full flat file.
Word Map on EC 2.3.1.60
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2.3.1.60
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baumannii
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amikacin
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tobramycin
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integrons
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aminoglycoside-modifying
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netilmicin
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aac3-ii
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aac6\'-i
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aph3\'-vi
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sisomicin
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aminoglycoside-resistant
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aada1a
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gentamicin-resistant
- 2.3.1.60
- baumannii
- amikacin
- tobramycin
- integrons
-
aminoglycoside-modifying
- netilmicin
-
aac3-ii
-
aac6\'-i
-
aph3\'-vi
- sisomicin
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aminoglycoside-resistant
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aada1a
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gentamicin-resistant
Reaction
Synonyms
3-N-aminoglycoside acetyltransferase, AAC, AAC(3)-I, aac(3)-Ia, AAC(3)-Ib, AAC(3)-IV, aacC1, acetyltransferase, gentamicin 3-, aminoglycoside 3-Nacetyltransferase I, aminoglycoside acetyltransferase, aminoglycoside acetyltransferase AAC(3)-1, aminoglycoside N-acetyltransferase, gentamicin acetyltransferase I, meta-AAC0005, meta-AAC0007, meta-AAC0012, More
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General Information
General Information on EC 2.3.1.60 - gentamicin 3-N-acetyltransferase
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physiological function
additional information
presence of genes encoding the following aminoglycoside-modifying enzymes: aph (3')-V1, aph (3')-Ia, aac (3)-Ia, aac (3) IIa, aac (6')-Ih, aac (6')-Ib and ant (2')-Ia responsible for resistance in 4 different groups of clinical isolates, overview
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aminoglycoside acetyltransferase gene aac(3)-Id confers resistance to gentamicin and sisomicin
physiological function
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the enzyme confers gentamicin resistance but retains geneticin susceptibility
physiological function
the enzyme confers high-level heterologous resistance to the aminoglycosides gentamicin C, sisomicin, and tobramycin
physiological function
the enzyme confers high-level heterologous resistance to the aminoglycosides gentamicin C, sisomicin, and tobramycin