2.3.1.60: gentamicin 3-N-acetyltransferase

This is an abbreviated version!
For detailed information about gentamicin 3-N-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.60

2.3.1.60

baumannii

amikacin

tobramycin

integrons

aminoglycoside-modifying

netilmicin

aac3-ii

aac6\'-i

aph3\'-vi

sisomicin

aminoglycoside-resistant

aada1a

gentamicin-resistant

Reaction

Synonyms

3-N-aminoglycoside acetyltransferase, AAC, AAC(3)-I, aac(3)-Ia, AAC(3)-Ib, AAC(3)-IV, aacC1, acetyltransferase, gentamicin 3-, aminoglycoside 3-Nacetyltransferase I, aminoglycoside acetyltransferase, aminoglycoside acetyltransferase AAC(3)-1, aminoglycoside N-acetyltransferase, gentamicin acetyltransferase I, meta-AAC0005, meta-AAC0007, meta-AAC0012, More

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.60 gentamicin 3-N-acetyltransferase

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
1	Activating Compound
51	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
2	Crystallization (Commentary)
5	General Information
1	General Stability
16	Inhibitors
11	Ki Value [mM]
3	KM Value [mM]
2	Localization
2	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
21	Organism
1	pH Optimum
1	pH Range
2	pH Stability
3	Purification (Commentary)
1	Reaction
1	Reaction Type
10	Reference
1	Source Tissue
1	Specific Activity [micromol/min/mg]
3	Storage Stability
38	Substrates and Products (Substrate)
2	Subunits
25	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Turnover Number [1/s]

Reference

top print

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Reference on EC 2.3.1.60 - gentamicin 3-N-acetyltransferase

Please use the Reference Search for a specific query.

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

637298

Williams, J.W.; Northrop, D.B.

Purification and properties of gentamicin acetyltransferase I

Biochemistry

125-131

1976

Escherichia coli, Escherichia coli C600

764855

637302

Williams, J.W.; Northrop, D.B.

Substrate specificity and structure-activity relationships of gentamicin acetyltransferase I. The dependence of antibiotic resistance upon substrate Vmax/Km values

J. Biol. Chem.

253

5908-5914

1978

Escherichia coli, Escherichia coli C600

681328

637303

Vliegenthart, John S.; Ketelaar-Van Gaalen, Petra A.G.; Van de Klundert, Jos A.M.

Identification of three genes coding for aminoglycoside-modifying enzymes by means of the polymerase chain reaction

J. Antimicrob. Chemother.

759-765

1990

Escherichia coli

2373662

706886

Ahmed, A.M.; Younis, E.E.; Osman, S.A.; Ishida, Y.; El-Khodery, S.A.; Shimamoto, T.

Genetic analysis of antimicrobial resistance in Escherichia coli isolated from diarrheic neonatal calves

Vet. Microbiol.

136

397-402

2009

Escherichia coli

19128900

736260

Atasoy, A.R.; Ciftci, I.H.; Petek, M.

Modifying enzymes related aminoglycoside: analyses of resistant Acinetobacter isolates

Int. J. Clin. Exp. Med.

2874-2880

2015

Acinetobacter baumannii (O05286)

25932248

755693

Xu, Z.; Stogios, P.J.; Quaile, A.T.; Forsberg, K.J.; Patel, S.; Skarina, T.; Houliston, S.; Arrowsmith, C.; Dantas, G.; Savchenko, A.

Structural and functional survey of environmental aminoglycoside acetyltransferases reveals functionality of resistance enzymes

ACS Infect. Dis.

653-665

2017

uncultured bacterium, uncultured bacterium (A0A059WV44), Pseudomonas aeruginosa (Q51407)

28756664

756303

Evangelisti, E.; Yunusov, T.; Shenhav, L.; Schornack, S.

N-acetyltransferase AAC(3)-I confers gentamicin resistance to Phytophthora palmivora and Phytophthora infestans

BMC Microbiol.

265

2019

Pseudomonas aeruginosa

31775609