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2.3.1.67: 1-alkylglycerophosphocholine O-acetyltransferase

This is an abbreviated version!
For detailed information about 1-alkylglycerophosphocholine O-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.67

Reaction

acetyl-CoA
+
1-alkyl-sn-glycero-3-phosphocholine
=
CoA
+
2-acetyl-1-alkyl-sn-glycero-3-phosphocholine

Synonyms

1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase, acetyl-CoA: lyso-PAF acetyltransferase, acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine 2-O-acetyltransferase, acetyl-CoA:1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase, acetyl-CoA:1-O-alkyl-sn-glycero-3-phosphocholine acetyltransferase, acetyl-CoA:lyso-PAF acetyltransferase, acetyl-CoA:lysoPAF acetyltransferase, acetyl-coenzyme A:1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase, acetyl-coenzymeA:lysoPAF acetyltransferase, acetyltransferase, 1-alkyl-2-lysolecithin, acetyltransferase, 1-alkylglycerophosphocholine, acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acyltransferase, blood platelet-activating factor acetyltransferase, lpafat1, LPCAT1, LPCAT2, lyso-GPC:acetyl CoA acetyltransferase, lyso-PAF acetyltransferase, lyso-PAF acetyltransferase:LPC acyltransferase 1, lyso-PAF AT, Lyso-PAF ATC, Lyso-PAF ATE, lyso-PAF-acetyltransferase, lyso-PAF-AcT, Lyso-PAF-AT, lyso-PAF:acetyl-CoA acetyltransferase, lyso-PAFAT, lyso-platelet activating factor:acetyl-CoA acetyltransferase, lyso-platelet-activating factor acetyltransferase, lyso-platelet-activating factor:acetyl-CoA acetyltransferase, lysoPAF-AT, lysoPAF:acetyl CoA acetyltransferase, lysoPAFAT, lysophosphatidylcholine acyltransferase (LPCAT2)/lyso-PAF acetyltransferase, lysophosphatidylcholine acyltransferase 1, mLysoPAFAT/LPCAT2, PAF acetyltransferase, platelet-activating factor acylhydrolase, platelet-activating factor-synthesizing enzyme

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.67 1-alkylglycerophosphocholine O-acetyltransferase

Expression

Expression on EC 2.3.1.67 - 1-alkylglycerophosphocholine O-acetyltransferase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
3-hexanoyloxy-2-methoxy-5-methyl-1,4-benzoquinone, 3-decanoyloxy-2-methoxy-5-methyl-1,4-benzoquinone, and 2-methoxy-5-methyl-3-tetradecanoyloxy-1,4-benzoquinone also inhibit the expression of the enzyme mRNA
fatty acid esters of fumigatin reduce lipopolysaccharide-stimulated transcription of lyso-PAF acetyltransferase/LPCAT2 mRNA in bone marrow-derived macrophages
lysoPAF-AT shows a significant activation after 1-h infection with a maximum activity at 2-h infection with Salmonella enteritidis
-
stimulation of enzyme expression by lipopolysaccharides
the specific activity of the enzyme is increased 6 h after meal consumption
-
under inflammatory conditions, LPCAT2, but not LPCAT1, is activated and upregulated to produce the platelet-activating factor
wine extracts (Robola and Cabernet Sauvignon) inhibit the enzyme activity 6 h after meal consumption
-