2.3.1.67: 1-alkylglycerophosphocholine O-acetyltransferase

This is an abbreviated version!
For detailed information about 1-alkylglycerophosphocholine O-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.67

2.3.1.67

paf-ah

acetylhydrolase

paf-cpt

cholinephosphotransferase

1-o-alkyl-2-acetyl-sn-glycero-3-phosphocholine

paf-acetylhydrolase

coa-independent

transacylase

dtt-insensitive

3hacetate

paf-synthesizing

1-o-alkyl-sn-glycero-3-phosphocholine

14carachidonic

phospholipase-a2

medicine

lppla2

analysis

drug development

Reaction

2-acetyl-1-alkyl-sn-glycero-3-phosphocholine

Synonyms

1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase, acetyl-CoA: lyso-PAF acetyltransferase, acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine 2-O-acetyltransferase, acetyl-CoA:1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase, acetyl-CoA:1-O-alkyl-sn-glycero-3-phosphocholine acetyltransferase, acetyl-CoA:lyso-PAF acetyltransferase, acetyl-CoA:lysoPAF acetyltransferase, acetyl-coenzyme A:1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase, acetyl-coenzymeA:lysoPAF acetyltransferase, acetyltransferase, 1-alkyl-2-lysolecithin, acetyltransferase, 1-alkylglycerophosphocholine, acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acyltransferase, blood platelet-activating factor acetyltransferase, lpafat1, LPCAT1, LPCAT2, lyso-GPC:acetyl CoA acetyltransferase, lyso-PAF acetyltransferase, lyso-PAF acetyltransferase:LPC acyltransferase 1, lyso-PAF AT, Lyso-PAF ATC, Lyso-PAF ATE, lyso-PAF-acetyltransferase, lyso-PAF-AcT, Lyso-PAF-AT, lyso-PAF:acetyl-CoA acetyltransferase, lyso-PAFAT, lyso-platelet activating factor:acetyl-CoA acetyltransferase, lyso-platelet-activating factor acetyltransferase, lyso-platelet-activating factor:acetyl-CoA acetyltransferase, lysoPAF-AT, lysoPAF:acetyl CoA acetyltransferase, lysoPAFAT, lysophosphatidylcholine acyltransferase (LPCAT2)/lyso-PAF acetyltransferase, lysophosphatidylcholine acyltransferase 1, mLysoPAFAT/LPCAT2, PAF acetyltransferase, platelet-activating factor acylhydrolase, platelet-activating factor-synthesizing enzyme

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.67 1-alkylglycerophosphocholine O-acetyltransferase

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Results	in table
18	Activating Compound
37	AA Sequence
8	Application
1	CAS Registry Number
8	Cloned(Commentary)
7	Cofactor
3	Disease/ Diagnostics
8	Expression
13	General Information
4	General Stability
63	IC50 Value
141	Inhibitors
17	KM Value [mM]
21	Localization
6	Metals/Ions
3	Molecular Weight [Da]
19	Natural Substrates/ Products (Substrates)
51	Organism
2	Pathway
29	pH Optimum
2	pH Range
2	Posttranslational Modification
10	Protein Variants
4	Purification (Commentary)
1	Reaction
5	Reaction Type
48	Reference
63	Source Tissue
24	Specific Activity [micromol/min/mg]
80	Substrates and Products (Substrate)
1	Subunits
76	Synonyms
1	Systematic Name
24	Temperature Optimum [°C]
1	Temperature Stability [°C]

Metals Ions

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Metals Ions on EC 2.3.1.67 - 1-alkylglycerophosphocholine O-acetyltransferase

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Ca2+

5 entries

selenium

Bos taurus

as a consequence of Se deficiency increased phospholipase D activity and phosphatidic acid production contribute to enhanced enzyme activity, which results in an overall increase in platelet activating factor. The regulation of enzyme activity by Se may constitute an important control mechanism for the maintenance of levels of platelet activating factor in endothelial cells

657735