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2.3.1.7: carnitine O-acetyltransferase

This is an abbreviated version!
For detailed information about carnitine O-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.7

Reaction

acetyl-CoA
+
carnitine
=
CoA
 +
O-acetylcarnitine

Synonyms

acetyl-CoA-carnitine O-acetyltransferase, acetylcarnitine transferase, acuJ, CarAc, CARAT, carnitine acetyl coenzyme A transferase, carnitine acetyl transferase, carnitine acetylase, carnitine acetyltransferase, carnitine acetyltransferase CAT2, carnitine acetyltransferase Cat2p, carnitine acetyltransferase Yat1p, carnitine acetyltransferase Yat2p, carnitine-acetyl-CoA transferase, CAT, CAT2, CATC, CRAT, CT-CAT, CTN1, CTN2, CTN3, H-CAT, P-CAT, S-CAT1, S-CAT2, Yat1

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.7 carnitine O-acetyltransferase

Cloned

Cloned on EC 2.3.1.7 - carnitine O-acetyltransferase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
both enzymes encoded by one gene, CT-CAT, cloned and expressed in Saccharomyces cerevisiae
-
cDNA cloned and sequenced
-
cDNA cloned, mapping of the corresponding gene to chromosome 9q34.1
-
cloning, sequencing and heterologous expression of cDNA
-
expressed as His-tag fusion protein in Escherichia coli
expressed in Escherichia coli BL21(DE3) cells
-
expressed in human skeletal myocytes
-
expressed in Saccharomyces cerevisiae and Escherichia coli
expression in Escherichia coli
expression in Escherichia coli or Saccharomyces cerevisiae
-
genomic DNA clone isolated from the yeast lambda EMBL library sequenced and expressed in Saccharomyces cerevisiae
-
hCAT, cloned and expressed in Escherichia coli
-
overexpressing CAT2, which encodes the major mitochondrial and peroxisomal carnitine acetyltransferase, on the formation of esters and other flavour compounds during fermentation and overexpression of a modified CAT2 that results in a protein that localizes to the cytosol. The overexpression of both forms of CAT2 resulted in a reduction in ester concentrations, especially in ethyl acetate and isoamyl acetate
residues 30-626 expressed as His-tag fusion protein in Escherichia coli
-
sequence analysis of full-length cDNA clone
single-gene product with multiple targeting signals
-