2.3.1.7: carnitine O-acetyltransferase

This is an abbreviated version!
For detailed information about carnitine O-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.7

2.3.1.7

peroxisomal

palmitoyltransferase

beta-oxidation

acyl-coas

l-carnitine

acyltransferases

clofibrate

palmitoyl-coa

acylcarnitine

proliferators

hypolipidemic

octanoyltransferase

cyanide-insensitive

propionylation

cardos

acetyl-l-carnitine

carbazole

carnitine-dependent

cronbach

alloy

1,9a-dioxygenase

coash

peroxisome-associated

palmitoylcarnitine

nafenopin

bezafibrate

ciprofibrate

food industry

analysis

medicine

Reaction

acetyl-CoA

+

carnitine

=

CoA

+

O-acetylcarnitine

Synonyms

acetyl-CoA-carnitine O-acetyltransferase, acetylcarnitine transferase, acuJ, CarAc, CARAT, carnitine acetyl coenzyme A transferase, carnitine acetyl transferase, carnitine acetylase, carnitine acetyltransferase, carnitine acetyltransferase CAT2, carnitine acetyltransferase Cat2p, carnitine acetyltransferase Yat1p, carnitine acetyltransferase Yat2p, carnitine-acetyl-CoA transferase, CAT, CAT2, CATC, CRAT, CT-CAT, CTN1, CTN2, CTN3, H-CAT, P-CAT, S-CAT1, S-CAT2, Yat1

ECTree

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.7 carnitine O-acetyltransferase

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Results	in table
6	Activating Compound
126	AA Sequence
12	Application
1	CAS Registry Number
19	Cloned(Commentary)
11	Crystallization (Commentary)
173	Disease/ Diagnostics
3	Expression
10	General Information
6	General Stability
3	IC50 Value
116	Inhibitors
37	Ki Value [mM]
188	KM Value [mM]
183	Localization
73	Molecular Weight [Da]
480	Natural Substrates/ Products (Substrates)
563	Organism
11	PDB ID
16	pH Optimum
6	pH Range
2	pH Stability
1	Posttranslational Modification
23	Protein Variants
57	Purification (Commentary)
5	Reaction
1	Reaction Type
156	Reference
233	Source Tissue
30	Specific Activity [micromol/min/mg]
12	Storage Stability
952	Substrates and Products (Substrate)
46	Subunits
97	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Temperature Stability [°C]
24	Turnover Number [1/s]

KI Value

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KI Value on EC 2.3.1.7 - carnitine O-acetyltransferase

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0.25

(+)-acetylcarnitine

-

-

2.1

(+)carnitine

-

-

0.89 - 4.72

(2R,6S:2S,6R)-6-carboxymethyl-2-hydroxy-2,4,4-trimethylmorpholinium chloride

show

1.6

3-(2,2,2-trimethylhydrazinium)-propionate

-

0.0625 mM carnitine

4.1

3-acetoxy-5,5-dimethylhexanoic acid

-

reverse direction

8.3

3-hydroxy-5,5-dimethylhexanoic acid

-

-

0.047 - 0.052

acetyl-CoA

show

0.81 - 0.98

acetyl-L-(-)-carnitine

show

920

acetylcarnitine

Rattus norvegicus

-

substrate DL-carnitine

2.6

Ca2+

Aspergillus niger

-

-

27

choline

-

-

0.015 - 0.021

CoASH

show

0.0046

Cu2+

Aspergillus niger

-

-

1 - 1.1

D-carnitine

show

2.3

deoxycarnitine

-

-

1.2

deoxynorcarnitine

-

-

71

DL-acetyl-beta-methylcholine

-

-

0.39

DL-acetylcarnitine

-

-

0.2 - 0.62

DL-carnitine

show

44

gamma-aminobutyrate

-

-

0.25 - 0.31

L-(-)-carnitine

show

1.5

Mg2+

Aspergillus niger

-

-

5

Mn2+

Aspergillus niger

-

-

0.016

palmitoyl-CoA

-

-

8 - 18.6

palmityl-CoA

show

12

Prostigmine

-

-

20.3

R-(+)-3-hydroxy-5,5-dimethylhexanoic acid

-

-

7.5

S-(-)-3-hydroxy-5,5-dimethylhexanoic acid

-

-

15

tensilon

-

-

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Release 2023.1 (January 2023)