2.3.1.7: carnitine O-acetyltransferase

This is an abbreviated version!
For detailed information about carnitine O-acetyltransferase, go to the full flat file.

Reaction

Synonyms

acetyl-CoA-carnitine O-acetyltransferase, acetylcarnitine transferase, acuJ, CarAc, CARAT, carnitine acetyl coenzyme A transferase, carnitine acetyl transferase, carnitine acetylase, carnitine acetyltransferase, carnitine acetyltransferase CAT2, carnitine acetyltransferase Cat2p, carnitine acetyltransferase Yat1p, carnitine acetyltransferase Yat2p, carnitine-acetyl-CoA transferase, CAT, CAT2, CATC, CRAT, CT-CAT, CTN1, CTN2, CTN3, H-CAT, P-CAT, S-CAT1, S-CAT2, Yat1

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.7 carnitine O-acetyltransferase

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Results	in table
6	Activating Compound
126	AA Sequence
12	Application
1	CAS Registry Number
19	Cloned(Commentary)
11	Crystallization (Commentary)
173	Disease/ Diagnostics
3	Expression
10	General Information
6	General Stability
3	IC50 Value
116	Inhibitors
37	Ki Value [mM]
188	KM Value [mM]
183	Localization
73	Molecular Weight [Da]
480	Natural Substrates/ Products (Substrates)
563	Organism
11	PDB ID
16	pH Optimum
6	pH Range
2	pH Stability
1	Posttranslational Modification
23	Protein Variants
57	Purification (Commentary)
5	Reaction
1	Reaction Type
156	Reference
233	Source Tissue
30	Specific Activity [micromol/min/mg]
12	Storage Stability
952	Substrates and Products (Substrate)
46	Subunits
97	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Temperature Stability [°C]
24	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 2.3.1.7 - carnitine O-acetyltransferase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

3-keto-4-pentenoyl-CoA + L-(-)carnitine

3-keto-4-pentenoylcarnitine + CoASH

Columba sp.

-

-

487412

-

-

?

acetoacetyl-CoA + L-(-)carnitine

O-acetoacetyl(-)carnitine + CoASH

Rattus norvegicus

-

-

487404

-

-

r

acetyl-CoA + (-)-norcarnitine

acetylnorcarnitine + CoASH

Sus scrofa

-

beta-hydroxy-gamma-dimethylaminobutyrate

487398

-

-

r

acetyl-CoA + (trishydroxymethyl)glycine

acetyl(trishydroxymethyl)glycine + CoASH

Columba sp.

-

-

487401

-

-

?

acetyl-CoA + carnitine

CoA + acetylcarnitine

Columba livia

-

-

704846

-

-

r

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

14 entries

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

19 entries

acetyl-CoA + choline

acetylcholine + CoA

Rattus norvegicus

-

low activity with wild-type enzyme. Mutant enzymes T465V/T467N/R518N and A106M/T465V/T467N/R518N show improved catalytic efficiency toward choline (Kcat/Km) compared with that of the wild type enzyme

672172

-

-

?

acetyl-CoA + choline

acetylcholine + CoASH

2 entries

acetyl-CoA + DL-beta-hydroxy-gamma-aminobutyrate

beta-hydroxybutyrate + CoASH

Sus scrofa

-

non-methylated derivative of carnitine

487398

-

-

r

acetyl-CoA + DL-norcarnitine

acetylnorcarnitine + CoASH

Sus scrofa

-

beta-hydroxy-gamma-dimethylaminobutyrate

487398

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

23 entries

acetyl-CoA + L-carnitine

CoA + O-acetylcarnitine

4 entries

acetyl-CoA + tris(hydroxymethyl)aminoethansulfonic acid

acetyl-tris(hydroxymethyl)aminoethansulfonic acid + CoASH

Columba sp.

-

-

487401

-

-

?

acetyl-CoA + tris(hydroxymethyl)aminomethane

acetyl-tris(hydroxymethyl)aminomethane + CoASH

Columba sp.

-

-

487401

-

-

?

acyl-CoA + carnitine

acylcarnitine + CoASH

23 entries

acyl-CoA + L-carnitine

CoA + O-acylcarnitine

3 entries

acylcarnitine + CoASH

acyl-CoA + carnitine

23 entries

bromoacetyl-CoA + L-(-)carnitine

bromoacetylcarnitine + CoASH

Columba sp.

-

-

487412

-

-

?

butyryl-CoA + carnitine

CoA + O-butyrylcarnitine

3 entries

butyryl-CoA + L-carnitine

CoA + O-butyryl-L-carnitine

Columba sp.

-

-

487423

-

-

?

butyryl-CoA + L-carnitine

CoA + O-butyrylcarnitine

3 entries

CoA + O-acetyl-L-carnitine

acetyl-CoA + L-carnitine

Bos taurus

-

-

487407

-

-

?

CoA + O-acetylcarnitine

acetyl-CoA + carnitine

Mus musculus

P47934

-

756008

-

-

r

decanoyl-CoA + carnitine

CoA + O-decanoylcarnitine

Rattus norvegicus

-

-

672172

-

-

?

decanoyl-CoA + carnitine

decanoylcarnitine + CoASH

4 entries

decanoylcarnitine + CoASH

decanoyl-CoA + carnitine

5 entries

hexanoyl-CoA + carnitine

CoA + O-hexanoylcarnitine

2 entries

hexanoyl-CoA + carnitine

hexanoylcarnitine + CoASH

5 entries

hexanoyl-CoA + L-carnitine

CoA + O-hexanoyl-L-carnitine

Homo sapiens

-

-

487416

-

-

?

hexanoylcarnitine + CoASH

hexanoyl-CoA + carnitine

4 entries

isobutyryl-CoA + carnitine

isobutyrylcarnitine + CoASH

Bos taurus

-

-

487407

-

-

r

isobutyrylcarnitine + CoASH

isobutyryl-CoA + carnitine

Bos taurus

-

-

487407

-

-

r

isovaleryl-CoA + carnitine

isovalerylcarnitine + CoASH

Bos taurus

-

-

487407

-

-

r

isovalerylcarnitine + CoASH

isovaleryl-CoA + carnitine

Bos taurus

-

-

487407

-

-

r

malonyl-CoA + L-(-)carnitine

malonylcarnitine + CoASH

Candida tropicalis

-

-

487405

-

-

r

malonylcarnitine + CoASH

malonyl-CoA + L-(-)carnitine

Candida tropicalis

-

slight transfer of the acyl group to carnitine

487405

-

-

r

n-butyryl-CoA + carnitine

n-butyrylcarnitine + CoASH

7 entries

n-butyrylcarnitine + CoASH

n-butyryl-CoA + carnitine

7 entries

n-valeryl-CoA + carnitine

n-valerylcarnitine + CoASH

Bos taurus

-

-

487407

-

-

r

n-valerylcarnitine + CoASH

n-valeryl-CoA + carnitine

Bos taurus

-

-

487407

-

-

r

O-acetoacetyl(-)carnitine + CoASH

acetoacetyl-CoA + L-(-)carnitine

Rattus norvegicus

-

-

487404

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

25 entries

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

23 entries

octanoyl-CoA + carnitine

CoA + O-octanoylcarnitine

3 entries

octanoyl-CoA + carnitine

octanoylcarnitine + CoASH

4 entries

octanoyl-CoA + L-carnitine

CoA + O-octanoylcarnitine

Homo sapiens

-

-

735697

-

-

?

octanoylcarnitine + CoASH

octanoyl-CoA + carnitine

4 entries

palmitoyl-CoA + carnitine

CoA + O-palmitoylcarnitine

Rattus norvegicus

-

wild-type enzyme shows no activity, mutant enzymes M564G and D356A/M564G show activity

672172

-

-

?

palmitoyl-CoA + L-carnitine

CoA + O-palmitoylcarnitine

Homo sapiens

-

-

735697

-

-

?

propionyl-CoA + carnitine

CoA + O-propionylcarnitine

Homo sapiens

P43155

-

756901

-

-

?

propionyl-CoA + L-(-)carnitine

propionylcarnitine + CoASH

7 entries

propionyl-CoA + L-carnitine

CoA + O-propionyl-L-carnitine

Columba sp.

-

-

487423

-

-

?

propionyl-CoA + L-carnitine

CoA + O-propionylcarnitine

3 entries

propionylcarnitine + CoASH

propionyl-CoA + L-(-)carnitine

7 entries

additional information

?

-

35 entries

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

Homo sapiens

-

-

659194, 660553

-

-

r

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

Homo sapiens

P43155

-

756901

-

-

?

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

Homo sapiens

P43155

-

659815

-

-

r

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

Homo sapiens

-

modulates acetyl-CoA and CoA availability for a wide range of acyl-transfer reactions, involved in fatty acid metabolism

659194, 660553

-

-

r

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

Homo sapiens

P43155

modulates acetyl-CoA and CoA availability for a wide range of acyl-transfer reactions, involved in fatty acid metabolism

659815

-

-

r

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

Mus musculus

-

-

657546, 659365, 660553

-

-

r

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

Mus musculus

P47934

-

674651

-

-

?

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

Mus musculus

P47934

-

756008

-

-

r

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

Mus musculus

-

modulates acetyl-CoA and CoA availability for a wide range of acyl-transfer reactions, involved in fatty acid metabolism

657546, 659365, 660553

-

-

r

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

Rattus norvegicus

-

-

672172

-

-

?

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

Rattus norvegicus

Q704S8

-

659372

-

-

r

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

Rattus norvegicus

Q704S8

modulates acetyl-CoA and CoA availability for a wide range of acyl-transfer reactions, involved in fatty acid metabolism

659372

-

-

r

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

Saccharomyces cerevisiae

P32796

-

673746

-

-

?

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

Saccharomyces cerevisiae

P32796

this reaction is important in transferring activated acetyl groups to the mitochondria and in regulating the acetyl-CoA/CoA pools within the cell

673746

-

-

?

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Aspergillus niger

-

-

487424

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Bos taurus

-

-

486295, 487400, 487404, 487407, 487418, 487423, 487424, 487429

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Camelus dromedarius

-

-

487421, 487422, 487423

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Candida albicans

-

-

487427

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Candida tropicalis

-

-

487402, 487405, 487406, 487410, 487411, 487413, 487415, 487418, 487424, 487425, 487426, 487427

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Cavia porcellus

-

-

487400, 487404

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Columba sp.

-

-

487397, 487399, 487400, 487401, 487403, 487404, 487405, 487406, 487407, 487408, 487410, 487412, 487414, 487418, 487419, 487421, 487422, 487423, 487424, 487426, 487428, 487431, 487432

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Cutaneotrichosporon curvatum

-

-

487424

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Cyberlindnera jadinii

-

-

487424

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Homo sapiens

-

-

487399, 487416, 487418, 487421, 487422, 487423, 487424, 487426, 487427, 487428, 487430, 487431, 487433

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Lipomyces starkeyi

-

-

487424

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Mus musculus

-

-

486295, 487413, 487420, 487421, 487422, 487423, 487424, 487428

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Mus musculus

P47934

-

487428

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Mus musculus

P47934

-

487433

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Oryctolagus cuniculus

-

-

487399, 487432

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Ovis aries

-

-

487397, 487400, 487407

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Rattus norvegicus

-

-

486295, 487403, 487404, 487406, 487407, 487408, 487410, 487414, 487416, 487418, 487421, 487422, 487423, 487424, 487429, 487430, 487432

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Saccharomyces cerevisiae

-

-

487418, 487421, 487424, 487425, 487426, 487428

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Sus scrofa

-

-

487397, 487398, 487403, 487404, 487406, 487416, 487422, 487424, 487428

-

-

r

acetyl-CoA + choline

acetylcholine + CoASH

Columba sp.

-

-

487399

-

-

?

acetyl-CoA + choline

acetylcholine + CoASH

Oryctolagus cuniculus

-

-

487399

-

-

?

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Aspergillus niger

-

-

487424

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Bos taurus

-

-

486295, 487400, 487404, 487407, 487418, 487423, 487424, 487429

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Camelus dromedarius

-

-

487421, 487422, 487423

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Candida albicans

-

-

487427

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Candida tropicalis

-

-

487402, 487405, 487406, 487410, 487411, 487413, 487415, 487418, 487424, 487425, 487426, 487427

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Cavia porcellus

-

-

487400, 487404

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Columba sp.

-

-

487397, 487399, 487400, 487401, 487403, 487404, 487405, 487406, 487407, 487408, 487410, 487412, 487414, 487418, 487419, 487421, 487422, 487423, 487424, 487426, 487428, 487431, 487432

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Cutaneotrichosporon curvatum

-

-

487424

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Cyberlindnera jadinii

-

-

487424

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Homo sapiens

-

-

487399, 487416, 487418, 487421, 487422, 487423, 487424, 487426, 487427, 487428, 487430, 487431, 487433

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Lipomyces starkeyi

-

-

487424

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Mus musculus

-

-

486295, 487413, 487420, 487421, 487422, 487423, 487424, 487428

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Mus musculus

P47934

-

487428

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Mus musculus

P47934

-

487433

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Mus musculus BALB/c

-

-

487420

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Mus musculus S3T3(ATCC CCL-92)

-

-

487428

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Oryctolagus cuniculus

-

-

487399, 487432

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Ovis aries

-

-

487397, 487400, 487407

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Rattus norvegicus

-

-

486295, 487403, 487404, 487406, 487407, 487408, 487410, 487414, 487416, 487418, 487421, 487422, 487423, 487424, 487429, 487430, 487432

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Rattus norvegicus Sprague-Dawley

-

-

487429

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Saccharomyces cerevisiae

-

-

487418, 487421, 487424, 487425, 487426, 487428

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Sus scrofa

-

-

487397, 487398, 487403, 487404, 487406, 487416, 487422, 487424, 487428

-

-

r

acetyl-CoA + L-(-)carnitine

O-acetylcarnitine + CoASH

Torulopsis bovina

-

-

486295, 487418

-

-

r

acetyl-CoA + L-carnitine

CoA + O-acetylcarnitine

Cavia porcellus

-

-

736607

-

-

r

acetyl-CoA + L-carnitine

CoA + O-acetylcarnitine

Homo sapiens

-

-

735697

-

-

?

acetyl-CoA + L-carnitine

CoA + O-acetylcarnitine

Mus musculus

-

-

736560

-

-

?

acetyl-CoA + L-carnitine

CoA + O-acetylcarnitine

Rattus norvegicus

-

-

736607

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Aspergillus niger

-

-

487424

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Bos taurus

-

-

486295, 487400, 487404, 487407, 487418, 487423, 487424, 487429

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Camelus dromedarius

-

-

487421, 487422, 487423

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Candida albicans

-

-

487427

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Candida tropicalis

-

-

487402, 487405, 487406, 487410, 487411, 487413, 487415, 487418, 487424, 487425, 487426, 487427

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Cavia porcellus

-

-

487400, 487404

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Columba sp.

-

-

487397, 487399, 487400, 487401, 487403, 487404, 487405, 487406, 487407, 487408, 487410, 487412, 487414, 487418, 487419, 487421, 487422, 487423, 487424, 487426, 487428, 487431, 487432

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Cutaneotrichosporon curvatum

-

-

487424

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Cyberlindnera jadinii

-

-

487424

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Homo sapiens

-

-

487399, 487416, 487418, 487421, 487422, 487423, 487424, 487426, 487427, 487428, 487430, 487431, 487433

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Lipomyces starkeyi

-

-

487424

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Mus musculus

-

-

486295, 487413, 487420, 487421, 487422, 487423, 487424, 487428

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Mus musculus

P47934

-

487428

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Mus musculus

P47934

-

487433

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Mus musculus BALB/c

-

-

487420

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Mus musculus S3T3(ATCC CCL-92)

-

-

487428

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Oryctolagus cuniculus

-

-

487399, 487432

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Ovis aries

-

-

487397, 487400, 487407

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Rattus norvegicus

-

-

486295, 487403, 487404, 487406, 487407, 487408, 487410, 487414, 487416, 487417, 487418, 487421, 487422, 487423, 487424, 487429, 487430, 487432

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Rattus norvegicus Sprague-Dawley

-

-

487429

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Saccharomyces cerevisiae

-

-

487418, 487421, 487424, 487425, 487426, 487428

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Sus scrofa

-

-

487397, 487398, 487403, 487404, 487406, 487416, 487422, 487424, 487428

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Torulopsis bovina

-

-

486295, 487418

-

-

r

acyl-CoA + L-carnitine

CoA + O-acylcarnitine

Homo sapiens

-

-

735903, 736268

-

-

?

acyl-CoA + L-carnitine

CoA + O-acylcarnitine

Mus musculus

-

-

735852

-

-

?

acyl-CoA + L-carnitine

CoA + O-acylcarnitine

Mus musculus

-

-

735906

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Aspergillus niger

-

-

487424

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Bos taurus

-

-

486295, 487400, 487404, 487407, 487418, 487423, 487424, 487429

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Camelus dromedarius

-

-

487421, 487422, 487423

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Candida albicans

-

-

487427

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Candida tropicalis

-

-

487402, 487405, 487406, 487410, 487411, 487413, 487415, 487418, 487424, 487425, 487426, 487427

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Cavia porcellus

-

-

487400, 487404

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Columba sp.

-

-

487397, 487399, 487400, 487401, 487403, 487404, 487405, 487406, 487407, 487408, 487410, 487412, 487414, 487418, 487419, 487421, 487422, 487423, 487424, 487426, 487428, 487431, 487432

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Cutaneotrichosporon curvatum

-

-

487424

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Cyberlindnera jadinii

-

-

487424

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Homo sapiens

-

-

487399, 487416, 487418, 487421, 487422, 487423, 487424, 487426, 487427, 487428, 487430, 487431, 487433

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Lipomyces starkeyi

-

-

487424

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Mus musculus

-

-

486295, 487413, 487420, 487421, 487422, 487423, 487424, 487428

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Mus musculus

P47934

-

487428

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Mus musculus

P47934

-

487433

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Mus musculus BALB/c

-

-

487420

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Mus musculus S3T3(ATCC CCL-92)

-

-

487428

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Oryctolagus cuniculus

-

-

487399, 487432

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Ovis aries

-

-

487397, 487400, 487407

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Rattus norvegicus

-

-

486295, 487403, 487404, 487406, 487407, 487408, 487410, 487414, 487416, 487417, 487418, 487421, 487422, 487423, 487424, 487429, 487430, 487432

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Rattus norvegicus Sprague-Dawley

-

-

487429

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Saccharomyces cerevisiae

-

-

487418, 487421, 487424, 487425, 487426, 487428

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Sus scrofa

-

-

487397, 487398, 487403, 487404, 487406, 487416, 487422, 487424, 487428

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Torulopsis bovina

-

-

486295, 487418

-

-

r

butyryl-CoA + carnitine

CoA + O-butyrylcarnitine

Mus musculus

-

-

659365

-

-

r

butyryl-CoA + carnitine

CoA + O-butyrylcarnitine

Rattus norvegicus

Q704S8

-

659372

-

-

r

butyryl-CoA + carnitine

CoA + O-butyrylcarnitine

Rattus norvegicus

-

wild-type enzyme shows maximal activity towards butyryl-CoA

672172

-

-

?

butyryl-CoA + L-carnitine

CoA + O-butyrylcarnitine

Cavia porcellus

-

-

736607

-

-

r

butyryl-CoA + L-carnitine

CoA + O-butyrylcarnitine

Homo sapiens

-

-

735697

-

-

?

butyryl-CoA + L-carnitine

CoA + O-butyrylcarnitine

Rattus norvegicus

-

preferred substrate

736607

-

-

r

decanoyl-CoA + carnitine

decanoylcarnitine + CoASH

Columba sp.

-

-

487406, 487408

-

-

r

decanoyl-CoA + carnitine

decanoylcarnitine + CoASH

Mus musculus

-

-

486295

-

-

r

decanoyl-CoA + carnitine

decanoylcarnitine + CoASH

Rattus norvegicus

-

-

486295, 487406, 487408, 487416

-

-

r

decanoyl-CoA + carnitine

decanoylcarnitine + CoASH

Sus scrofa

-

-

487406, 487416

-

-

r

decanoylcarnitine + CoASH

decanoyl-CoA + carnitine

Columba sp.

-

-

487406, 487408

-

-

r

decanoylcarnitine + CoASH

decanoyl-CoA + carnitine

Homo sapiens

-

-

487416

-

-

r

decanoylcarnitine + CoASH

decanoyl-CoA + carnitine

Mus musculus

-

-

486295

-

-

r

decanoylcarnitine + CoASH

decanoyl-CoA + carnitine

Rattus norvegicus

-

-

486295, 487406, 487408, 487416

-

-

r

decanoylcarnitine + CoASH

decanoyl-CoA + carnitine

Sus scrofa

-

-

487406, 487416

-

-

r

hexanoyl-CoA + carnitine

CoA + O-hexanoylcarnitine

Rattus norvegicus

Q704S8

very low activity

659372

-

-

r

hexanoyl-CoA + carnitine

CoA + O-hexanoylcarnitine

Rattus norvegicus

-

mutant enzymes M564G and D356A/M564G show maximal activity towards hexanoyl-CoA

672172

-

-

?

hexanoyl-CoA + carnitine

hexanoylcarnitine + CoASH

Columba sp.

-

-

487406, 487408

-

-

r

hexanoyl-CoA + carnitine

hexanoylcarnitine + CoASH

Mus musculus

-

-

486295

-

-

r

hexanoyl-CoA + carnitine

hexanoylcarnitine + CoASH

Mus musculus

P47934

-

674651

-

-

?

hexanoyl-CoA + carnitine

hexanoylcarnitine + CoASH

Rattus norvegicus

-

-

486295, 487406, 487408

-

-

r

hexanoyl-CoA + carnitine

hexanoylcarnitine + CoASH

Sus scrofa

-

-

487406

-

-

r

hexanoylcarnitine + CoASH

hexanoyl-CoA + carnitine

Columba sp.

-

-

487406, 487408

-

-

r

hexanoylcarnitine + CoASH

hexanoyl-CoA + carnitine

Mus musculus

-

-

486295

-

-

r

hexanoylcarnitine + CoASH

hexanoyl-CoA + carnitine

Rattus norvegicus

-

-

486295, 487406, 487408

-

-

r

hexanoylcarnitine + CoASH

hexanoyl-CoA + carnitine

Sus scrofa

-

-

487406

-

-

r

n-butyryl-CoA + carnitine

n-butyrylcarnitine + CoASH

Bos taurus

-

-

486295, 487407, 487423

-

-

r

n-butyryl-CoA + carnitine

n-butyrylcarnitine + CoASH

Camelus dromedarius

-

-

487422, 487423

-

-

r

n-butyryl-CoA + carnitine

n-butyrylcarnitine + CoASH

Candida albicans

-

-

487427

-

-

r

n-butyryl-CoA + carnitine

n-butyrylcarnitine + CoASH

Candida tropicalis

-

-

487405, 487427

-

-

r

n-butyryl-CoA + carnitine

n-butyrylcarnitine + CoASH

Homo sapiens

-

-

487416, 487422, 487423, 487427

-

-

r

n-butyryl-CoA + carnitine

n-butyrylcarnitine + CoASH

Mus musculus

-

-

486295, 487422, 487423

-

-

r

n-butyryl-CoA + carnitine

n-butyrylcarnitine + CoASH

Rattus norvegicus

-

-

486295, 487407, 487408, 487416, 487422, 487423

-

-

r

n-butyrylcarnitine + CoASH

n-butyryl-CoA + carnitine

Bos taurus

-

-

486295, 487407, 487423

-

-

r

n-butyrylcarnitine + CoASH

n-butyryl-CoA + carnitine

Camelus dromedarius

-

-

487422, 487423

-

-

r

n-butyrylcarnitine + CoASH

n-butyryl-CoA + carnitine

Candida albicans

-

-

487427

-

-

r

n-butyrylcarnitine + CoASH

n-butyryl-CoA + carnitine

Candida tropicalis

-

-

487405, 487427

-

-

r

n-butyrylcarnitine + CoASH

n-butyryl-CoA + carnitine

Homo sapiens

-

-

487416, 487422, 487423, 487427

-

-

r

n-butyrylcarnitine + CoASH

n-butyryl-CoA + carnitine

Mus musculus

-

-

486295, 487422, 487423

-

-

r

n-butyrylcarnitine + CoASH

n-butyryl-CoA + carnitine

Rattus norvegicus

-

-

486295, 487407, 487408, 487416, 487422, 487423

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Aspergillus niger

-

-

487424

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Bos taurus

-

-

486295, 487400, 487404, 487418, 487423, 487424, 487429

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Bos taurus

-

mitochondrial fatty acid transport

487407

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Camelus dromedarius

-

-

487421, 487422, 487423

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Candida albicans

-

key enzyme for the translocation of acetyl units between intracellular compartments

487427

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Candida tropicalis

-

-

487402, 487405, 487406, 487410, 487411, 487413, 487415, 487418, 487424, 487425, 487426, 487427

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Cavia porcellus

-

-

487400, 487404

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Columba sp.

-

-

487397, 487399, 487400, 487401, 487403, 487404, 487405, 487406, 487407, 487408, 487410, 487412, 487414, 487418, 487419, 487421, 487422, 487423, 487424, 487426, 487428, 487431, 487432

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Cutaneotrichosporon curvatum

-

-

487424

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Cyberlindnera jadinii

-

-

487424

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Homo sapiens

-

-

487399, 487416, 487418, 487421, 487422, 487423, 487424, 487426, 487427, 487428, 487430, 487431, 487433

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Lipomyces starkeyi

-

-

487424

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Mus musculus

-

-

486295, 487413, 487420, 487421, 487422, 487423, 487424, 487428

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Mus musculus

P47934

-

487428

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Mus musculus

P47934

-

487433

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Mus musculus BALB/c

-

-

487420

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Mus musculus S3T3(ATCC CCL-92)

-

-

487428

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Oryctolagus cuniculus

-

-

487399, 487432

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Ovis aries

-

-

487397, 487400, 487407

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Rattus norvegicus

-

-

486295, 487403, 487404, 487406, 487407, 487408, 487410, 487414, 487416, 487418, 487421, 487422, 487423, 487424, 487429, 487430

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Rattus norvegicus

-

key mitochondrial enzyme for fuel utilization, essential functions are to regenerate CoA, which allows peroxisomal beta-oxidation to proceed, and to facilitate transport of acetyl moieties to mitochondria for oxidation

487432

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Rattus norvegicus Sprague-Dawley

-

-

487429

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Saccharomyces cerevisiae

-

-

487421, 487424, 487425, 487426, 487428

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Saccharomyces cerevisiae

-

acetate metabolism, enzyme transports activated acetyl group from the cytosol into the mitochondrial matrix

487418

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Sus scrofa

-

-

487397, 487398, 487403, 487404, 487406, 487416, 487422, 487424, 487428

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Aspergillus niger

-

-

487424

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Bos taurus

-

-

486295, 487400, 487404, 487407, 487418, 487423, 487424, 487429

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Camelus dromedarius

-

-

487421, 487422, 487423

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Candida albicans

-

-

487427

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Candida tropicalis

-

-

487402, 487405, 487406, 487410, 487411, 487413, 487415, 487418, 487424, 487425, 487426, 487427

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Cavia porcellus

-

-

487400, 487404

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Columba sp.

-

-

487397, 487399, 487400, 487401, 487403, 487404, 487405, 487406, 487407, 487408, 487410, 487412, 487414, 487418, 487419, 487421, 487422, 487423, 487424, 487426, 487428, 487431, 487432

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Cutaneotrichosporon curvatum

-

-

487424

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Cyberlindnera jadinii

-

-

487424

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Homo sapiens

-

-

487399, 487416, 487418, 487421, 487422, 487423, 487424, 487426, 487427, 487428, 487430, 487431, 487433

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Lipomyces starkeyi

-

-

487424

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Mus musculus

-

-

486295, 487413, 487420, 487421, 487422, 487423, 487424, 487428

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Mus musculus

P47934

-

487428

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Mus musculus

P47934

-

487433

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Mus musculus BALB/c

-

-

487420

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Mus musculus S3T3(ATCC CCL-92)

-

-

487428

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Oryctolagus cuniculus

-

-

487399, 487432

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Ovis aries

-

-

487397, 487400, 487407

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Rattus norvegicus

-

-

486295, 487403, 487404, 487406, 487407, 487408, 487410, 487414, 487416, 487418, 487421, 487422, 487423, 487424, 487429, 487430, 487432

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Rattus norvegicus Sprague-Dawley

-

-

487429

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Saccharomyces cerevisiae

-

-

487418, 487421, 487424, 487425, 487426, 487428

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Sus scrofa

-

-

487397, 487398, 487403, 487404, 487406, 487416, 487422, 487424, 487428

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + L-(-)carnitine

Torulopsis bovina

-

-

486295, 487418

-

-

r

octanoyl-CoA + carnitine

CoA + O-octanoylcarnitine

Homo sapiens

P43155

-

756901

-

-

?

octanoyl-CoA + carnitine

CoA + O-octanoylcarnitine

Rattus norvegicus

-

-

672172

-

-

?

octanoyl-CoA + carnitine

CoA + O-octanoylcarnitine

Rattus norvegicus

Q704S8

very low activity

659372

-

-

r

octanoyl-CoA + carnitine

octanoylcarnitine + CoASH

Bos taurus

-

-

486295, 487407

-

-

r

octanoyl-CoA + carnitine

octanoylcarnitine + CoASH

Homo sapiens

-

-

487416, 487427

-

-

r

octanoyl-CoA + carnitine

octanoylcarnitine + CoASH

Mus musculus

-

-

486295

-

-

r

octanoyl-CoA + carnitine

octanoylcarnitine + CoASH

Rattus norvegicus

-

-

486295, 487407, 487408, 487416

-

-

r

octanoylcarnitine + CoASH

octanoyl-CoA + carnitine

Bos taurus

-

-

486295, 487407

-

-

r

octanoylcarnitine + CoASH

octanoyl-CoA + carnitine

Homo sapiens

-

-

487416, 487427

-

-

r

octanoylcarnitine + CoASH

octanoyl-CoA + carnitine

Mus musculus

-

-

486295

-

-

r

octanoylcarnitine + CoASH

octanoyl-CoA + carnitine

Rattus norvegicus

-

-

486295, 487407, 487408, 487416

-

-

r

propionyl-CoA + L-(-)carnitine

propionylcarnitine + CoASH

Bos taurus

-

-

486295, 487404, 487407, 487423

-

-

r

propionyl-CoA + L-(-)carnitine

propionylcarnitine + CoASH

Camelus dromedarius

-

-

487422, 487423

-

-

r

propionyl-CoA + L-(-)carnitine

propionylcarnitine + CoASH

Candida albicans

-

-

487427

-

-

r

propionyl-CoA + L-(-)carnitine

propionylcarnitine + CoASH

Candida tropicalis

-

-

487405, 487406, 487410, 487427

-

-

r

propionyl-CoA + L-(-)carnitine

propionylcarnitine + CoASH

Homo sapiens

-

-

487416, 487422, 487423, 487427

-

-

r

propionyl-CoA + L-(-)carnitine

propionylcarnitine + CoASH

Mus musculus

-

-

486295, 487422, 487423

-

-

r

propionyl-CoA + L-(-)carnitine

propionylcarnitine + CoASH

Rattus norvegicus

-

-

486295, 487404, 487406, 487407, 487410, 487416, 487417, 487422, 487423

-

-

r

propionyl-CoA + L-carnitine

CoA + O-propionylcarnitine

Cavia porcellus

-

preferred substrate

736607

-

-

r

propionyl-CoA + L-carnitine

CoA + O-propionylcarnitine

Homo sapiens

-

-

735697

-

-

?

propionyl-CoA + L-carnitine

CoA + O-propionylcarnitine

Rattus norvegicus

-

-

736607

-

-

r

propionylcarnitine + CoASH

propionyl-CoA + L-(-)carnitine

Bos taurus

-

-

486295, 487404, 487407, 487423

-

-

r

propionylcarnitine + CoASH

propionyl-CoA + L-(-)carnitine

Camelus dromedarius

-

-

487422, 487423

-

-

r

propionylcarnitine + CoASH

propionyl-CoA + L-(-)carnitine

Candida albicans

-

-

487427

-

-

r

propionylcarnitine + CoASH

propionyl-CoA + L-(-)carnitine

Candida tropicalis

-

-

487405, 487406, 487410, 487427

-

-

r

propionylcarnitine + CoASH

propionyl-CoA + L-(-)carnitine

Homo sapiens

-

-

487416, 487422, 487423, 487427

-

-

r

propionylcarnitine + CoASH

propionyl-CoA + L-(-)carnitine

Mus musculus

-

-

486295, 487422, 487423

-

-

r

propionylcarnitine + CoASH

propionyl-CoA + L-(-)carnitine

Rattus norvegicus

-

-

486295, 487404, 487406, 487407, 487410, 487416, 487417, 487422, 487423

-

-

r

additional information

?

-

Bos taurus

-

D-carnitine is no substrate

487407

-

-

?

additional information

?

-

Camelus dromedarius

-

palmitoyl-CoA is no substrate

487423

-

-

?

additional information

?

-

Candida albicans

-

octanoyl-CoA and palmitoyl-CoA are no substrates

487427

-

-

?

additional information

?

-

Candida albicans

-

carnitine acetyltransferases are required for growth on non-fermentable carbon sources but not for pathogenesis in Candida albicans

688876

-

-

?

additional information

?

-

Candida albicans

-

carnitine acetyltransferases are required for growth on non-fermentable carbon sources but not for pathogenesis in Candida albicans. Strains lacking CTN1 or CTN2 are unable to grow on ethanol or acetate as sole carbon source

688876

-

-

?

additional information

?

-

Candida tropicalis

-

crotonyl-CoA is no substrate

487405

-

-

?

additional information

?

-

Candida tropicalis

-

octanoyl-CoA and palmitoyl-CoA are no substrates

487427

-

-

?

additional information

?

-

Candida tropicalis

-

pentanoyl-CoA, hexanoyl-CoA, decanoyl-CoA and palmitoyl-CoA are no substrates

487406

-

-

?

additional information

?

-

Columba sp.

-

-

487403

-

-

?

additional information

?

-

Columba sp.

-

-

487404

-

-

?

additional information

?

-

Columba sp.

-

-

487405

-

-

?

additional information

?

-

Columba sp.

-

-

487406

-

-

?

additional information

?

-

Columba sp.

-

-

487423

-

-

?

additional information

?

-

Columba sp.

-

hydroxyethylpiperazineethansulfonic acid is no substrate

487401

-

-

?

additional information

?

-

Columba sp.

-

3-hydroxy-5,5-dimethylhexanoic acid, 3-acetoxy-5,5-dimethylhexanoic acid, R-(+)-3-hydroxy-5,5-dimethylhexanoic acid and S-(-)-3-hydroxy-5,5-dimethylhexanoic acid are not substrates

487419

-

-

?

additional information

?

-

Columba sp.

-

D-carnitine is no substrate

487407

-

-

?

additional information

?

-

Columba sp.

-

D-carnitine is no substrate

487419

-

-

?

additional information

?

-

Homo sapiens

-

palmitoyl-CoA is no substrate

487416

-

-

?

additional information

?

-

Homo sapiens

-

palmitoyl-CoA is no substrate

487423

-

-

?

additional information

?

-

Homo sapiens

-

the enzyme shows some activity with acyl-CoAs of longer chain length including C12- and C14-CoA, but not with C16-CoA. Trans-2-enoyl-CoA intermediates such as trans-2-ene-C4-CoA (crotonyl-CoA, trans-2-C4:1-CoA), trans-2-ene-3-methyl-C4-CoA (3-methylcrotonyl-CoA), and trans-2-ene-2-methyl-C4-CoA are poor substrates for the enzyme and no activity is found with dicarboxylic acyl-CoA esters

735697

-

-

?

additional information

?

-

Rattus norvegicus

-

-

486295

-

-

?

additional information

?

-

Rattus norvegicus

-

-

487406

-

-

?

additional information

?

-

Rattus norvegicus

-

-

487423

-

-

?

additional information

?

-

Rattus norvegicus

-

palmityl-CoA does not act as a substrate for the liver enzyme

487403

-

-

?

additional information

?

-

Rattus norvegicus

-

O-acetyl-(+)-carnitine and reduced glutathione will not serve as substrates, succinyl-CoA or beta-hydroxy-betamethylglutaryl-CoA are no substrates

487404

-

-

?

additional information

?

-

Rattus norvegicus

Q704S8

wild type enzyme is almost inactive towards longer chain fatty acids, some mutations increases activity towards longer chain fatty acids

659372

-

-

?

additional information

?

-

Saccharomyces cerevisiae

-

carnitine acetyltransferases catalyse the reversible reaction between carnitine and acetyl-CoA to form acetylcarnitine and free CoA. This reaction is important in transferring activated acetyl groups to the mitochondria and in regulating the acetyl-CoA/CoA pools within the cell

673746

-

-

?

additional information

?

-

Saccharomyces cerevisiae

P32796

carnitine acetyltransferases catalyse the reversible reaction between carnitine and acetyl-CoA to form acetylcarnitine and free CoA. This reaction is important in transferring activated acetyl groups to the mitochondria and in regulating the acetyl-CoA/CoA pools within the cell

673746

-

-

?

additional information

?

-

Saccharomyces cerevisiae

-

CAT2 contributes to the response to oxidative stress

686262

-

-

?

additional information

?

-

Saccharomyces cerevisiae

P32796

CAT2 contributes to the response to oxidative stress

686262

-

-

?

additional information

?

-

Sus scrofa

-

-

487403

-

-

?

additional information

?

-

Sus scrofa

-

-

487404

-

-

?

additional information

?

-

Sus scrofa

-

-

487406

-

-

?

additional information

?

-

Sus scrofa

-

only (-) optical isomers are substrates, unnatural (+) isomers are competitive inhibitors

487398

-

-

?

additional information

?

-

Torulopsis bovina

-

no carnitine acyltransferase activity with acyl CoAs of carbon chain lengths greater than 3

486295

-

-

?