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2.3.1.71: glycine N-benzoyltransferase

This is an abbreviated version!
For detailed information about glycine N-benzoyltransferase, go to the full flat file.

Reaction

benzoyl-CoA
+
glycine
=
CoA
+
hippurate

Synonyms

aralkyl-CoA:glycine N-acyltransferase, benzoyl CoA-amino acid N-acyltransferase, benzoyl-CoA:glycine N-acyltransferase, benzoyltransferase, glycine, GlyAT, glycine N-acyltransferase, GNAT

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.71 glycine N-benzoyltransferase

Inhibitors

Inhibitors on EC 2.3.1.71 - glycine N-benzoyltransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3'-dephospho-CoA
-
-
benzoylalanine
-
-
benzoylasparagine
-
-
benzoylglutamic acid
-
-
benzoylglycine
-
-
benzoylserine
-
-
CoA
-
in absence of KCl, 0.1 mM CoA inhibits activity over 40% irrespective of the concentration of glycine. In presence of KCl, CoA inhibits activity only slightly, less than 10%. In presence of potassium phosphate the inhibition is reduced to less than 2%. 2.5 mM, almost complete inhibition of salt-free enzyme
glycolic acid
-
hippuric acid
indolacetyl-CoA
-
-
Li+
-
110 mM
Na+
-
110 mM
oleoyl-CoA
-
p-hydroxymercuribenzoate
-
1 mM, 24°C, 90% inhibition after 40 min
phenylacetyl-CoA
-
-
potassium phosphate
-
-
Rb+
-
110 mM