2.3.1.81: aminoglycoside 3-N-acetyltransferase

This is an abbreviated version!
For detailed information about aminoglycoside 3-N-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.81

2.3.1.81

gentamicin

amikacin

tobramycin

integrons

aminoglycoside-modifying

apramycin

gentamicin-resistant

aac6\'-ib-cr

blatem

netilmicin

sisomicin

aac3-ii

aac6'-ie

dfra12

aminoglycoside-resistant

apramycin-resistant

ant6-ia

butirosin

quinolone-resistant

arbekacin

ribostamycin

blashv

lividomycin

oqxab

aph3\'-iiia

isepamicin

2'-n-acetyltransferase

fortimicin

amikacin-resistant

synthesis

medicine

Reaction

Synonyms

3'-aminoglycoside acetyltransferase, 3-N-acetyltransferase, 3-N-aminoglycoside acetyltransferase, AAC, AAC (3)-IIIb, AAC(3), AAC(3)-Id, AAC(3)-Ig acetyltransferase, Aac(3)-IIIb, AAC(3)-IV, AAC(3)-XI, AAC(6')-APH(2''), AAC-IIIb, AAC-VIa, aac3-Ia, AAC3-IV aminoglycoside acetyltransferase, AacC-A7 acetyltransferase, aminoglycoside 3-acetyltransferase, aminoglycoside 3-acetyltransferase-IIIb, aminoglycoside 3-N-acetyltransferase, aminoglycoside 3-N-acetyltransferase type XI, aminoglycoside acetyltransferase, aminoglycoside acetytransferase, aminoglycoside N(3)-acetyltransferase III, aminoglycoside N3-acetyltransferase, aminoglycoside N3-acetyltransferase-IIIb, aminoglycoside N3-acetyltransferase-VIa, Eis, Eis2, Enhanced in Intracellular Survival, More, RbmI

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.81 aminoglycoside 3-N-acetyltransferase

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Results	in table
6278	AA Sequence
5	Application
1	CAS Registry Number
16	Cloned(Commentary)
1	Cofactor
4	Crystallization (Commentary)
9	Disease/ Diagnostics
7	General Information
3	General Stability
2	IC50 Value
29	Inhibitors
27	kcat/KM [mM/s]
2	Ki Value [mM]
71	KM Value [mM]
7	Localization
3	Metals/Ions
8	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
45	Organism
77	PDB ID
4	pH Optimum
1	pI Value
1	Posttranslational Modification
2	Protein Variants
7	Purification (Commentary)
1	Reaction
1	Reaction Type
38	Reference
1	Source Tissue
3	Specific Activity [micromol/min/mg]
2	Storage Stability
171	Substrates and Products (Substrate)
3	Subunits
52	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
1	Temperature Stability [°C]
66	Turnover Number [1/s]

KCat KM Value

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KCat KM Value on EC 2.3.1.81 - aminoglycoside 3-N-acetyltransferase

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89 - 2600

acetyl-CoA

4 entries

dibekacin

2 entries

4700

gentamicin C1

Enterobacter cloacae

pH 7.6, 25°C

758305

6100

gentamicin C2

Enterobacter cloacae

pH 7.6, 25°C

758305

10600 - 11200

kanamycin A

2 entries

17 - 34400

kanamycin B

5 entries

9500

lividomycin A

Pseudomonas aeruginosa

pH 7.6, 25°C

718870

malonyl-CoA

Pseudomonas aeruginosa

cosubstrate kanamycin A, pH 7.6, 25°C

718871

120

n-propionyl-CoA

Pseudomonas aeruginosa

cosubstrate kanamycin A, pH 7.6, 25°C

718871

9100

neomycin B

Pseudomonas aeruginosa

pH 7.6, 25°C

718870

10800

paromomycin

Pseudomonas aeruginosa

pH 7.6, 25°C

718870

10600

ribostamycin

Pseudomonas aeruginosa

pH 7.6, 25°C

718870

1600

sisomicin

Enterobacter cloacae

pH 7.6, 25°C

758305

30700 - 33400

sisomycin

2 entries

400 - 60500

tobramycin

3 entries