Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.3.1.85: fatty-acid synthase system

This is an abbreviated version!
For detailed information about fatty-acid synthase system, go to the full flat file.

Word Map on EC 2.3.1.85

Reaction

acetyl-CoA
+ 7 malonyl-CoA + 14 NADPH + 14 H+ =
hexadecanoate
+ 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O

Synonyms

F09E10.3 protein, FAS, FAS-II, FASI, FASII, FASN, fatty acid synthase, fatty acid synthase I, fatty acid synthase II, fatty acid synthase type 2, fatty-acid synthase, type 2 dissociative FAS, type 2 fatty acid synthase, type II fatty acid synthase, yeast fatty acid synthase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.85 fatty-acid synthase system

Cloned

Cloned on EC 2.3.1.85 - fatty-acid synthase system

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
domain I with acetyl and malonyl transacetylase activity and beta-hydroxyacyl dehydratase activity
-
expressed in Saccharomyces cerevisiae oar1DELTA cells
expression in Escherichia coli
full length cDNA, cDNA encoding domain I and cDNA encoding domains II and III
-
gene sequences
-
individual overexpression of all components of fatty acid synthase in Escherichia coli
-
transacyclase domain
-
wild-type and mutant enzymes are expressed in Sf9 cells
-