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2.3.1.87: aralkylamine N-acetyltransferase

This is an abbreviated version!
For detailed information about aralkylamine N-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.87

Reaction

acetyl-CoA
+
a 2-arylethylamine
=
CoA
 +
an N-acetyl-2-arylethylamine

Synonyms

AA-NAT, AANAT, AANAT1, AANAT2, AANAT3, AANATL7, AATNATL2, acetyl-CoA:aralkylamine N-acetyltransferase, acetyltransferase, arylalkylamine N-, arylalkylamine N-acetyltransferase, arylalkylamine N-acetyltransferase 1, arylalkylamine N-acetyltransferase 1a, arylalkylamine N-acetyltransferase 1b, arylalkylamine N-acetyltransferase 2, arylalkylamine N-acetyltransferase like 7, arylalkylamine N-acetyltransferase-2, Bm-iAANAT, Eis, hAANAT, More, MSMEG_3513, N-acetyltransferase, NAT, oAANAT, PA4534, PaaNAT, Rv2416c, serotonin acetylase, serotonin acetyltransferase, serotonin N-acetyltransferase, serotonin-N-acetyltransferase, SNA, SNAT, SNAT1, SNAT2

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.87 aralkylamine N-acetyltransferase

KM Value

KM Value on EC 2.3.1.87 - aralkylamine N-acetyltransferase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.47
2,5-dimethoxyphenylethylamine
-
pH 6.8, 37°C
0.34 - 3.46
2-(2,3-dichlorophenyl)-ethylamine
0.9 - 2.74
2-(2-chlorophenyl)-ethylamine
1.76
2-(3,4-dihydroxyphenyl)-ethylamine
-
pH 6.8, 37°C
0.62 - 1.31
2-(3-chlorophenyl)-ethylamine
1.1 - 1.65
2-(3-fluorophenyl)-ethylamine
0.75 - 1.55
2-(4-bromophenyl)-ethylamine
2.33
2-(4-chlorophenyl)ethylamine
-
pH 6.8, 37°C
1.28 - 2.2
2-(4-fluorophenyl)-ethylamine
0.98 - 1.91
2-(p-fluorophenyl)-ethylamine
1.405
2-(p-nitrophenyl)-ethylamine
-
pH 6.8, 37°C
1.17 - 1.58
2-(p-tolyl)-ethylamine
1.37
2-fluorophenylethylamine
0.49 - 1.3
2-methoxyphenylethylamine
0.17 - 9.5
2-Phenylethylamine
0.18
3-(trifluoromethyl)phenethylamine
-
wild-type, pH 8.0, 22°C
2.07
3-methoxy-2-phenylethylamine
-
pH 6.8, 37°C
0.061
3-methoxyphenethylamine
-
wild-type, pH 8.0, 22°C
1.815
3-methoxytyramine
-
pH 6.8, 37°C
0.009
5-benzyloxytryptamine
-
wild-type, pH 8.0, 22°C
0.024
5-hydroxytryptamine
-
-
0.042 - 0.63
5-methoxytryptamine
1.9
6-Hydroxydopamine
pH 6.8, 37°C
0.00031 - 1.11
acetyl-CoA
0.0019
Arachidonoyl-CoA
pH 8.0, temperature not specified in the publication
0.26
beta-methylphenethylamine
-
wild-type, pH 8.0, 22°C
0.009 - 0.173
beta-phenylethylamine
0.0018 - 0.006
butanoyl-CoA
0.11 - 11
dopamine
0.04
hexanoyl-CoA
-
wild-type, pH 8.0, 22°C
0.0023 - 16
histamine
0.18 - 0.23
methoxytryptamine
0.05 - 0.17
norepinephrine
0.002 - 30
octopamine
0.0036
oleoyl-CoA
pH 8.0, temperature not specified in the publication
0.011
p-phenetidine
-
-
0.0099
palmitoyl-CoA
pH 8.0, temperature not specified in the publication
0.32
phenethylamine
-
wild-type, pH 8.0, 22°C
0.34 - 11
Phenylethylamine
0.066 - 0.47
propionyl-CoA
0.05 - 13
serotonin
0.006
stearoyl-CoA
pH 8.0, temperature not specified in the publication
0.0017 - 4.3
tryptamine
0.0015 - 57
tyramine
additional information
additional information
-