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female. The left gland contains higher activity than the right gland
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non-diapause eggs and diapause eggs
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ciliar body epithelial cells
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AANAT2 is expressed only in the muscular layer
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strongly expressed in the head, fat body, midgut, and integument tubules of 5th instar larvae
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abundant expression in flower
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AANAT2 is expressed only in the muscular layer
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esophagus, stomach, pyloric ceca, foregut, midgut, hindgut. AANAT2 is expressed only in the muscular layer of all segments. No significant differences are obtained among the different segments evaluated
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in foregut AANAT activity shows a daily rhythm while in hindgut significant but not rhythmic levels of AANAT activity are found. The active isoform in gut is AANAT1
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AANAT2 is expressed only in the muscular layer
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isozyme AANAT2 developmental expression pattern, overview
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isoforms Aanat1a and Aanat1b display a wide and distinct distribution in the nervous system and peripheral tissues
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photoreceptor cells, ependymal cells of the 3rd ventricle and discrete cells of the suprachiasmatic area. Expression of AANAT2 and absence of AANAT2
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mainly pars tuberalis, much less than in pineal gland, probably different regulation
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AANAT2 is expressed only in the muscular layer
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AANAT-specific immunoreactivity is observed in the nuclei of spinal neurons, and is significantly increased in aged dog spinal neurons compared to young adult spinal neurons. Melatonin receptor type 1B-specific immunoreactivity is found in the cytoplasm of spinal neurons, and is predominantly increased in the margin of the neuron cytoplasm in aged spinal cord compared to that in the young adult dogs
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AANAT2 is expressed only in the muscular layer
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the enzymatic activity is higher in adult than in pupal brain. No difference is observed between day and night in the pupal brain and adult brain
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highest level of activity at night
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suprachiasmatic nucleus
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of 3rd instar larvae, adult heads
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strongly expressed in the head, fat body, midgut, and integument tubules of 5th instar larvae
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strongly expressed in the head, fat body, midgut, and integument tubules of 5th instar larvae
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abundant expression in young leaf
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in liver significant but not rhythmic levels of AANAT activity are found
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non-inducible
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non-inducible
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strongly expressed in the head, fat body, midgut, and integument tubules of 5th instar larvae
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AANAT2 is expressed only in the muscular layer
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female
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cultured photoreceptor cells of embryonic retina
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from fish in different phases of the annual breeding cycle, and pineal organ culture
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transcripts are detected almost exclusively in the pineal gland
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Esox sp.
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exposure of dark-adapted animals to near ultraviolet light significantly decreases melatonin content and the activity of serotonin N-acetyltransferase
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4fold increase at night
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the enzyme catalyzes the first step in melatonin biosynthesis, melatonin biosynthesis follows a day and night rhythm, which is different in fasted, fed, and refed fish, overview
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inducible
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rhythmic expression of adenylyl cyclase VI contributes to the differential regulation of serotonin N-acetyltransferase by bradykinin in rat pineal glands
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inducible
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pineal gland-specific isozyme AANAT2 is specifically expressed in pineal opsin-immunoreactive photoreceptor cells, developmental expression pattern, s significant 60fold reduction in Aanat2 expression occurs just before metamorphosis, overview
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photoreceptor cells, enzyme activity is regulated by circadian system, the photoperiodic control is direct in fish and frogs and indirect in mammals. Structural and functional evolution of the melatonin-producing units in vertebrates, overview
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treatment of pinealocytes with norepinephrine causes an increase in the mRNA and protein levels of MKP-1 and AA-NAT, as well as in the AA-NAT activity
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traces of transcripts are detected
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cultured photoreceptor cells
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cultured photoreceptor cells of embryonic retina
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AANAT activity is low during the daytime, increases rapidly early in the night and beginsto decline in anticipation of dawn
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photic regulation of arylalkylamine N-acetyltransferase binding to 14-3-3 proteins in retinal photoreceptor cells
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4fold increase at night
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photoreceptor cells, ependymal cells of the 3rd ventricle and discrete cells of the suprachiasmatic area. Expression of AANAT2 and absence of AANAT2
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retina-specific isozyme AANAT1
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photoreceptor layer, inner nuclear layer. Low activity during the night and high activity during the day. Activity starts to increase during the second part of the night and reaches its maximal levels at dawn
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activity is elevated at night and rapidly inhibited by light
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testicular acessory gland
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additional information
tissue expression pattern of wild-type and mutant enzymes, overview. No expression in ovary, testis, midgut, fatbody, hemozyte, trachea, and Malpighian gland
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additional information
tissue expression pattern of wild-type and mutant enzymes, overview. No expression in ovary, testis, midgut, fatbody, hemozyte, trachea, and Malpighian gland
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additional information
tissue expression pattern of wild-type and mutant enzymes, overview. No expression in ovary, testis, midgut, fatbody, hemozyte, trachea, and Malpighian gland
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additional information
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tissue expression pattern of wild-type and mutant enzymes, overview. No expression in ovary, testis, midgut, fatbody, hemozyte, trachea, and Malpighian gland
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additional information
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offspring populations are maintained on Phaseolus vulgaris leaves
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