2.3.1.9: acetyl-CoA C-acetyltransferase
This is an abbreviated version!
For detailed information about acetyl-CoA C-acetyltransferase, go to the full flat file.
Word Map on EC 2.3.1.9
-
2.3.1.9
-
ketone
-
mevalonate
-
hmg-coa
-
acetoacetate
-
beta-oxidation
-
3-hydroxy-3-methylglutaryl-coa
-
beta-ketothiolase
-
2-methyl-3-hydroxybutyrate
-
3-hydroxybutyrate
-
acetoacetyl-coenzyme
-
ketoacidotic
-
ketogenesis
-
tiglylglycine
-
aacts
-
coa-transferase
-
2-methylacetoacetate
-
thiolytic
-
3-oxoacyl-coas
-
3-ketothiolase
-
3-hydroxyacyl-coa
-
coash
-
3-hydroxybutyryl-coa
-
lyso-paf
-
ketone-body
-
synthesis
-
analysis
-
biofuel production
- 2.3.1.9
- ketone
- mevalonate
- hmg-coa
- acetoacetate
-
beta-oxidation
- 3-hydroxy-3-methylglutaryl-coa
- beta-ketothiolase
- 2-methyl-3-hydroxybutyrate
- 3-hydroxybutyrate
-
acetoacetyl-coenzyme
-
ketoacidotic
-
ketogenesis
-
tiglylglycine
-
aacts
-
coa-transferase
- 2-methylacetoacetate
-
thiolytic
- 3-oxoacyl-coas
- 3-ketothiolase
- 3-hydroxyacyl-coa
- coash
- 3-hydroxybutyryl-coa
-
lyso-paf
-
ketone-body
- synthesis
- analysis
- biofuel production
Reaction
2 acetyl-CoA
=
Synonyms
2-methylacetoacetyl-CoA thiolase, 3-ketoacyl-CoA (T1)-like thiolase, 3-ketoacyl-CoA thiolase, 3-ketoacyl-coenzyme A thiolase, 3-oxothiolase, A1887, AACT, AACT1, AACT2, ACAT, ACAT1, ACAT2, ACCT, acetoacetyl CoA thiolase, acetoacetyl-CoA acetyltransferase, acetoacetyl-CoA C-acetyltransferase, acetoacetyl-CoA thiolase, acetoacetyl-CoA thiolase T2, acetyl coenzyme A thiolase, acetyl-CoA acetyltransferase, acetyl-CoA C-acetyltransferase, acetyl-CoA:N-acetyltransferase, acetyltransferase, acetyl coenzyme A, ACOAT, ACTRANS, AFUB_000550, AtoB, beta-acetoacetyl coenzyme A thiolase, beta-ketoacyl-CoA thiolase, beta-ketothiolase, CT, cytosolic acetoacetyl-CoA thiolase, cytosolic acetoacetyl-CoA thiolase 1, cytosolic acetoacetyl-CoA thiolase 2, ERG10, Erg10A, HFX_1022, HFX_1023, HFX_6003, HFX_6004, KACT, MmgA, Msed_0656, MSM-13 thiolase, OsAT1, phaA, ReH16_B0759, thiolase II, ThL, Tneu_0249, type II thiolase
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Reference on EC 2.3.1.9 - acetyl-CoA C-acetyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sliwkowski, M.X.; Hartmanis, M.G.N.
Simultaneous single-step purification of thiolase and NADP-dependent 3-hydroxybutyryl-CoA dehydrogenase from Clostridium kluyveri
Anal. Biochem.
141
344-347
1984
Clostridium kluyveri
Kurihara, T.; Ueda, M.; Tanaka, A.
Peroxisomal acetoacetyl-CoA thiolase and 3-ketoacyl-CoA thiolase from an n-alkane-utilizing yeast, Candida tropicalis: purification and characterization
J. Biochem.
106
474-478
1989
Candida tropicalis
Olowe, Y.; Schulz, H.
Regulation of thiolases from pig heart. Control of fatty acid oxidation in heart
Eur. J. Biochem.
109
425-429
1980
Sus scrofa
Feigenbaum, J.; Schulz, H.
Thiolases of Escherichia coli: purification and chain length specificities
J. Bacteriol.
122
407-411
1975
Escherichia coli
Oeljeklaus, S.; Fischer, K.; Gerhardt, B.
Glyoxysomal acetoacetyl-CoA thiolase and 3-oxoacyl-CoA thiolase from sunflower cotyledons
Planta
214
597-607
2002
Helianthus annuus
Kanayama, N.; Ueda, M.; Atomi, H.; Tanaka, A.
Genetic evaluation of physiological functions of thiolase isoenzymes in the n-alkane-assimilating yeast Candida tropicalis
J. Bacteriol.
180
690-698
1998
Candida tropicalis (Q12598), Candida tropicalis
Lobo, S.; Florova, G.; Reynolds, K.A.
A Streptomyces collinus thiolase with novel acetyl-CoA:acyl carrier protein transacylase activity
Biochemistry
40
11955-11964
2001
Streptomyces collinus
Stern, J.R.; Drummond, G.I.; Coon, M.J.; Del Campillo, A.
Enzymes of ketone body metabolism. I. Purification of an acetoacetate-synthesizing enzyme from ox liver
J. Biol. Chem.
235
313-317
1960
Bos taurus
Lynen, F.; Ochoa, S.
Enzymes of fatty acid metabolism
Biochim. Biophys. Acta
12
299-314
1953
Clostridium kluyveri, Sus scrofa
Nishimura, T.; Saito, T.; Tomita, K.
Purification and properties of beta-ketothiolase from Zoogloea ramigera
Arch. Microbiol.
116
21-27
1978
Zoogloea ramigera
Clinkenbeard, K.D.; Sugiyama, T.; Lane, M.D.
Cytosolic acetoacetyl-CoA thiolase from chicken liver
Methods Enzymol.
35 B
167-173
1975
Gallus gallus
-
Holland, P.C.; Clark, M.G.; Bloxham, D.P.
Inactivation of pig heart thiolase by 3-butynoyl coenzyme A, 3-pentynoyl coenzyme A, and 4-bromocrotonyl coenzyme A
Biochemistry
12
3309-3315
1973
Sus scrofa
Clinkenbeard, K.D.; Sugiyama, T.; Moss, J.; Reed, W.D.; Lane, M.D.
Molecular and catalytic properties of cytosolic acetoacetyl coenzyme A thiolase from avian liver
J. Biol. Chem.
248
2275-2284
1973
Gallus gallus
Hartmanis, M.G.N.; Stadtman, T.C.
Isolation of a selenium-containing thiolase from Clostridium kluyveri: identification of the selenium moiety as selenomethionine
Proc. Natl. Acad. Sci. USA
79
4912-4916
1982
Clostridium kluyveri
Middleton, B.
The kinetic mechanism and properties of the cytoplasmic acetoacetyl-coenzyme A thiolase from rat liver
Biochem. J.
139
109-121
1974
Rattus norvegicus
Bloxham, D.P.; Chalkley, R.A.; Coghlin, S.J.; Salam, W.
Synthesis of chloromethyl ketone derivatives of fatty acids. Their use as specific inhibitors of acetoacetyl-coenzyme A thiolase, cholesterol biosynthesis and fatty acid synthesis
Biochem. J.
175
999-1011
1978
Sus scrofa
Huth, W.; Jonas, R.; Wunderlich, I.; Seubert, W.
On the mechanism of ketogenesis and its control. Purification, kinetic mechanism and regulation of different forms of mitochondrial acetoacetyl-CoA thiolases from ox liver
Eur. J. Biochem.
59
475-489
1975
Bos taurus
Schwabe, D.; Huth, W.
Immunochemical aspects, molecular and kinetic properties of multiple forms of acetyl-CoA acetyltransferase from rat liver mitochondria
Biochim. Biophys. Acta
575
112-120
1979
Rattus norvegicus
Jonas, R.; Huth, W.
Acetyl-CoA acetyltransferase from bovine liver mitochondria. Molecular properties of multiple forms
Biochim. Biophys. Acta
527
379-390
1978
Bos taurus
Huth, W.; Dierich, C.; von Oeynhausen, V.; Seubert, W.
Multiple mitochondrial forms of acetoacetyl-CoA thiolase in rat liver: possible regulatory role in ketogenesis
Biochem. Biophys. Res. Commun.
56
1069-1077
1974
Rattus norvegicus
Davis, J.T.; Moore, R.N.; Imperiali, B.; Pratt, A.J.; Kobayashi, K.; Masamune, S.; Sinskey, A.J.; Walsh, C.T.; Fukui, T.; Tomita, K.
Biosynthetic thiolase from zoogloea ramigera. I. Preliminary characterization and analysis of proton transfer reaction
J. Biol. Chem.
262
82-89
1987
Zoogloea ramigera
Davis, J.T.; Chen, H.H.; Moore, R.; Nishitani, Y.; Masamune, S.; Sinskey, A.J.; Walsh, C.T.
Biosynthetic thiolase from Zoogloea ramigera. II. Inactivation with haloacetyl CoA analogs
J. Biol. Chem.
262
90-96
1987
Zoogloea ramigera
Peoples, O.P.; Masamune, S.; Walsh, S.T.; Sinskey, A.J.
Biosynthetic thiolase from Zoogloea ramigera. III. Isolation and characterization of the structural gene
J. Biol. Chem.
262
97-102
1987
Zoogloea ramigera, Zoogloea ramigera (P07256)
Palmer, M.A.J.; Differding, E.; Gamboni, R.; Williams, S.F.; Peoples, O.P.; Walsh, C.T.; Sinskey, A.J.; Masamune, S.
Biosynthetic thiolase from Zoogloea ramigera. Evidence for a mechanism involving Cys-378 as the active site base
J. Biol. Chem.
266
8369-8375
1991
Zoogloea ramigera
Wiesenborn, D.P.; Rudolph, F.B.; Papoutsakis, E.T.
Thiolase from Clostridium acetobutylicum ATCC 824 and its role in the synthesis of acids and solvents
Appl. Environ. Microbiol.
54
2717-2722
1988
Clostridium acetobutylicum
Suzuki, F.; Zahler, W.L.; Emerich, D.W.
Acetoacetyl-CoA thiolase of Bradyrhizobium japonicum bacteroids: purification and properties
Arch. Biochem. Biophys.
254
272-281
1987
Bradyrhizobium japonicum
Greenspan, M.D.; Yudkovitz, J.B.; Chen, J.S.; Hanf, D.P.; Chang, M.N.; Chiang, P.Y.C.; Chabala, J.C.; Alberts, A.W.
The inhibition of cytoplasmic acetoacetyl-CoA thiolase by a triyne carbonate (L-660, 631)
Biochem. Biophys. Res. Commun.
163
548-553
1989
Rattus norvegicus
Duncombe, G.R.; Frerman, F.E.
Molecular and catalytic properties of the acetoacetyl-coenzyme A thiolase of Escherichia coli
Arch. Biochem. Biophys.
176
159-170
1976
Escherichia coli
O'Connell, M.A.; Orr, G.; Shapiro, L.
Purification and characterization of fatty acid beta-oxidation enzymes from Caulobacter crescentus
J. Bacteriol.
172
997-1004
1990
Caulobacter vibrioides
Anderson, V.E.; Bahnson, B.J.; Wlassics, I.D.
The reaction of acetyldithio-CoA, a readily enolized anaolg of acetyl-CoA with thiolase from Zoogloea ramigera
J. Biol. Chem.
266
6255-6261
1990
Zoogloea ramigera
-
Heijden, R.v.d.; Verpoorte, R.; Duine, J.A.
Biosynthesis of 3S-hydroxy-3-methylglutaryl-coenzyme A in Catharanthus roseus: Acetoacetyl-CoA thiolase and HMG-CoA synthase show similar chromatographic behavior
Plant Physiol. Biochem.
32
807-812
1994
Catharanthus roseus
-
Kanayama, N.; Himeda, Y.; Atomi, H.; Ueda, M.; Tanaka, A.
Expression of acetoacetyl-CoA thiolase isoenzyme genes of n-alkane-assimilating yeast, Candida tropicalis: isoenzymes in two intracellular compartments are derived from the same genes
J. Biochem.
122
616-621
1997
Candida tropicalis, Rhizobium sp.
Kim, S.A.; Copeland, L.
Acetyl coenzyme A acetyltransferase of Rhizobium sp. (Cicer) strain CC 1192
Appl. Environ. Microbiol.
63
3432-3437
1997
Rhizobium sp.
Honda, A.; Salen, G.; Nguyen, L.B.; Xu, G.; Tint, G.S.; Batta, A.K.; Shefer, S.
Regulation of early cholesterol biosynthesis in rat liver: effects of sterols, bile acids, lovastatin, and BM 15.766 on 3-hydroxy-3-methylglutaryl coenzyme A synthase and acetoacetyl coenzyme A thiolase activities
Hepatology
27
154-159
1998
Rattus norvegicus
Modis, Y.; Wierenga, R.K.
A biosynthetic thiolase in complex with a reaction intermediate: the crystal structure provides new insights into the catalytic mechanism
Structure
7
1279-1290
1999
Zoogloea ramigera
Antonenkov, V.D.; Croes, K.; Waelkens, E.; Van Veldhoven, P.P.; Mannaerts, G.P.
Identification, purification and characterization of an acetoacetyl-CoA thiolase from rat liver peroxisomes
Eur. J. Biochem.
267
2981-2990
2000
Rattus norvegicus
Kursula, P.; Ojala, J.; Lambeir, A.M.; Wierenga, R.K.
The catalytic cycle of biosynthetic thiolase: a conformational journey of an acetyl group through four binding modes and two oxyanion holes
Biochemistry
41
15543-15556
2002
Zoogloea ramigera (P07097)
Hedl, M.; Sutherlin, A.; Wilding, E.I.; Mazzulla, M.; McDevitt, D.; Lane, P.; Burgner, J.W.; Lehnbeuter, K.R.; Stauffacher, C.V.; Gwynn, M.N.; Rodwell, V.W.
Enterococcus faecalis acetoacetyl-coenzyme A thiolase/3-hydroxy-3-methylglutaryl-coenzyme A reductase, a dual-function protein of isopentenyl diphosphate biosynthesis
J. Bacteriol.
184
2116-2122
2002
Enterococcus faecalis
Liu, T.; Liu, S.J.; Xue, Y.; Ma, Y.; Zhou, P.
Purification and characterization of an extremely halophilic acetoacetyl-CoA thiolase from a newly isolated Halobacterium strain ZP-6
Extremophiles
6
97-102
2002
Halobacterium sp., Halobacterium sp. ZP-6
Fukao, T.; Matsuo, N.; Zhang, G.X.; Urasawa, R.; Kubo, T.; Kohno, Y.; Kondo, N.
Single base substitutions at the initiator codon in the mitochondrial acetoacetyl-CoA thiolase (ACAT1/T2) gene result in production of varying amounts of wild-type T2 polypeptide
Hum. Mutat.
21
587-592
2003
Homo sapiens
Kursula, P.; Sikkilae, H.; Fukao, T.; Kondo, N.; Wierenga, R.K.
High resolution crystal structures of human cytosolic thiolase (CT): A comparison of the active sites of human CT, bacterial thiolase, and bacterial KAS I
J. Mol. Biol.
347
189-201
2005
Escherichia coli, Zoogloea ramigera (P07097), Zoogloea ramigera, Homo sapiens (Q9BWD1), Homo sapiens
Sakurai, S.; Fukao, T.; Haapalainen, A.M.; Zhang, G.; Yamada, K.; Lilliu, F.; Yano, S.; Robinson, P.; Gibson, M.K.; Wanders, R.J.; Mitchell, G.A.; Wierenga, R.K.; Kondo, N.
Kinetic and expression analyses of seven novel mutations in mitochondrial acetoacetyl-CoA thiolase (T2): Identification of a K(m) mutant and an analysis of the mutational sites in the structure
Mol. Genet. Metab.
90
370-378
2007
Homo sapiens
Treberg, J.R.; Crockett, E.L.; Driedzic, W.R.
Activation of liver carnitine palmitoyltransferase-1 and mitochondrial acetoacetyl-CoA thiolase is associated with elevated ketone body levels in the elasmobranch Squalus acanthias
Physiol. Biochem. Zool.
79
899-908
2006
Squalus acanthias
Haapalainen, A.M.; Merilaeinen, G.; Pirilae, P.L.; Kondo, N.; Fukao, T.; Wierenga, R.K.
Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase: the importance of potassium and chloride ions for its structure and function
Biochemistry
46
4305-4321
2007
Homo sapiens
Santhanam, S.; Venkatraman, A.; Ramakrishna, B.S.
Impairment of mitochondrial acetoacetyl CoA thiolase activity in the colonic mucosa of patients with ulcerative colitis
Gut
56
1543-1549
2007
Homo sapiens
Fukao, T.; Boneh, A.; Aoki, Y.; Kondo, N.
A novel single-base substitution (c.1124A>G) that activates a 5-base upstream cryptic splice donor site within exon 11 in the human mitochondrial acetoacetyl-CoA thiolase gene
Mol. Genet. Metab.
94
417-421
2008
Homo sapiens
Reddick, J.; Williams, J.
The mmgA gene from Bacillus subtilis encodes a degradative acetoacetyl-CoA thiolase
Biotechnol. Lett.
30
1045-1050
2008
Bacillus subtilis
Ahumada, I.; Caira, A.; Hemmerlin, A.; Gonzalez, V.; Pateraki, I.; Bach, T.; Rodriguez-Concepcion, M.; Campos, N.; Boronat, A.
Characterisation of the gene family encoding acetoacetyl-CoA thiolase in Arabidopsis
Funct. Plant Biol.
35
1100-1111
2008
Arabidopsis thaliana (Q8S4Y1), Arabidopsis thaliana (Q9FIK7)
Fujii, T.; Ito, K.; Katsuma, S.; Nakano, R.; Shimada, T.; Ishikawa, Y.
Molecular and functional characterization of an acetyl-CoA acetyltransferase from the adzuki bean borer moth Ostrinia scapulalis (Lepidoptera: Crambidae)
Insect Biochem. Mol. Biol.
40
74-78
2009
Ostrinia scapulalis (B7XEI5), Ostrinia scapulalis
Dyer, J.H.; Maina, A.; Gomez, I.D.; Cadet, M.; Oeljeklaus, S.; Schiedel, A.C.
Cloning, expression and purification of an acetoacetyl CoA thiolase from sunflower cotyledon
Int. J. Biol. Sci.
5
736-744
2009
Helianthus annuus (D2IH11)
Battilana, J.; Costantini, L.; Emanuelli, F.; Sevini, F.; Segala, C.; Moser, S.; Velasco, R.; Versini, G.; Stella Grando, M.
The 1-deoxy-D: -xylulose 5-phosphate synthase gene co-localizes with a major QTL affecting monoterpene content in grapevine
Theor. Appl. Genet.
118
653-669
2009
Vitis vinifera x Vitis vinifera, Vitis vinifera x Vitis riparia
Thuemmler, S.; Dupont, D.; Acquaviva, C.; Fukao, T.; de Ricaud, D.
Different clinical presentation in siblings with mitochondrial acetoacetyl-CoA thiolase deficiency and identification of two novel mutations
Tohoku J. Exp. Med.
220
27-31
2010
Homo sapiens
Tanaka, T.; Shima, Y.; Ogawa, N.; Nagayama, K.; Yoshida, T.; Ohmachi, T.
Expression, identification and purification of Dictyostelium acetoacetyl-CoA thiolase expressed in Escherichia coli
Int. J. Biol. Sci.
7
9-17
2011
Dictyostelium discoideum (Q86AD9)
Soto, G.; Stritzler, M.; Lisi, C.; Alleva, K.; Pagano, M.E.; Ardila, F.; Mozzicafreddo, M.; Cuccioloni, M.; Angeletti, M.; Ayub, N.D.
Acetoacetyl-CoA thiolase regulates the mevalonate pathway during abiotic stress adaptation
J. Exp. Bot.
62
5699-5711
2011
Medicago sativa (D0EUY6), Medicago sativa
Jin, H.; Song, Z.; Nikolau, B.J.
Reverse genetic characterization of two paralogous acetoacetyl CoA thiolase genes in Arabidopsis reveals their importance in plant growth and development
Plant J.
70
1015-1032
2012
Arabidopsis thaliana (Q8S4Y1), Arabidopsis thaliana (Q9FIK7)
Hou, J.; Feng, B.; Han, J.; Liu, H.; Zhao, D.; Zhou, J.; Xiang, H.
Haloarchaeal-type beta-ketothiolases involved in poly(3-hydroxybutyrate-co-3-hydroxyvalerate) synthesis in Haloferax mediterranei
Appl. Environ. Microbiol.
79
5104-5111
2013
Haloferax mediterranei (I3R3D1 and I3R3D0), Haloferax mediterranei (I3RA72 and I3RA71), Haloferax mediterranei, Haloferax mediterranei DSM 1411 (I3R3D1 and I3R3D0), Haloferax mediterranei DSM 1411 (I3RA72 and I3RA71)
Hawkins, A.B.; Adams, M.W.; Kelly, R.M.
Conversion of 4-hydroxybutyrate to acetyl coenzyme A and its anapleurosis in the Metallosphaera sedula 3-hydroxypropionate/4-hydroxybutyrate carbon fixation pathway
Appl. Environ. Microbiol.
80
2536-2545
2014
Metallosphaera sedula (A4YEH9), Metallosphaera sedula DSM 5348 (A4YEH9)
Ramos-Vera, W.H.; Weiss, M.; Strittmatter, E.; Kockelkorn, D.; Fuchs, G.
Identification of missing genes and enzymes for autotrophic carbon fixation in crenarchaeota
J. Bacteriol.
193
1201-1211
2011
Pyrobaculum neutrophilum (B1YB71), Pyrobaculum neutrophilum DSM 2338 (B1YB71)
Janardan, N.; Harijan, R.K.; Kiema, T.R.; Wierenga, R.K.; Murthy, M.R.
Structural characterization of a mitochondrial 3-ketoacyl-CoA (T1)-like thiolase from Mycobacterium smegmatis
Acta Crystallogr. Sect. D
71
2479-2493
2015
Mycolicibacterium smegmatis
Kim, J.; Kim, K.
Purification, crystallization and preliminary X-ray diffraction analysis of 3-ketoacyl-CoA thiolase A1887 from Ralstonia eutropha H16
Acta Crystallogr. Sect. F
71
758-762
2015
Cupriavidus necator (Q0KAI3), Cupriavidus necator, Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1 (Q0KAI3)
Kim, J.; Kim, K.J.
Crystal structure and biochemical properties of ReH16_A1887, the 3-ketoacyl-CoA thiolase from Ralstonia eutropha H16
Biochem. Biophys. Res. Commun.
459
547-552
2015
Cupriavidus necator (Q0KAI3), Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1 (Q0KAI3)
Zhong, Z.; Norvienyeku, J.; Yu, J.; Chen, M.; Cai, R.; Hong, Y.; Chen, L.; Zhang, D.; Wang, B.; Zhou, J.; Lu, G.; Chen, X.; Wang, Z.
Two different subcellular-localized Acetoacetyl-CoA acetyltransferases differentiate diverse functions in Magnaporthe oryzae
Fungal Genet. Biol.
83
58-67
2015
Pyricularia oryzae, Pyricularia oryzae Ku80
Kim, J.; Kim, K.J.
Crystal structure and biochemical characterization of a 3-ketoacyl-CoA thiolase from Ralstoniaeutropha H16
Int. J. Biol. Macromol.
82
425-431
2016
Cupriavidus necator (Q0K368), Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1 (Q0K368)
Yun, E.J.; Kwak, S.; Kim, S.R.; Park, Y.C.; Jin, Y.S.; Kim, K.H.
Production of (S)-3-hydroxybutyrate by metabolically engineered Saccharomyces cerevisiae
J. Biotechnol.
209
23-30
2015
Saccharomyces cerevisiae, Saccharomyces cerevisiae BY4741
Isezaki, N.; Sekiba, A.; Itagaki, S.; Nagayama, K.; Ochiai, H.; Ohmachi, T.
Dictyostelium acetoacetyl-CoA thiolase is a dual-localizing enzyme that localizes to peroxisomes, mitochondria and the cytosol
Microbiology
161
1471-1484
2015
Dictyostelium discoideum, Dictyostelium discoideum Ax-3
Kim, S.; Jang, Y.S.; Ha, S.C.; Ahn, J.W.; Kim, E.J.; Lim, J.H.; Cho, C.; Ryu, Y.S.; Lee, S.K.; Lee, S.Y.; Kim, K.J.
Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum
Nature Commun.
6
8410
2015
Clostridium acetobutylicum (P45359)
Lin, J.; Qu, H.; Chen, G.; He, L.; Xu, Y.; Xie, Z.; Ren, M.; Sun, J.; Li, S.; Chen, W.; Chen, X.; Wang, X.; Li, X.; Liang, C.; Huang, Y.; Yu, X.
Clonorchis sinensis acetoacetyl-CoA thiolase: identification and characterization of its potential role in surviving in the bile duct
Parasit. Vectors
8
125
2015
Clonorchis sinensis (G7YHN5), Clonorchis sinensis
Vishwakarma, R.; Rub, R.; Singh, S.; Sonawane, P.; Srivastava, S.; Kumari, U.; Santosh Kumar, R.; Khan, B.
Molecular cloning, biochemical characterization, and differential expression of an acetyl-CoA C-acetyltransferase gene (AACT) of Brahmi (Bacopa monniera)
Plant Mol. Biol. Rep.
31
547-557
2013
Bacopa monnieri (D9U856)
-
Pantazaki, A.; Ioannou, A.; Kyriakidis, D.
A thermostable beta-ketothiolase of polyhydroxyalkanoates (PHAs) in Thermus thermophilus Purification and biochemical properties
Mol. Cell. Biochem.
269
27-36
2005
Thermus thermophilus
Ithayaraja, M.; Janardan, N.; Wierenga, R.; Savithri, H.; Murthy, M.
Crystal structure of a thiolase from Escherichia coli at 1.8 A resolution
Acta Crystallogr. F Struct. Biol. Commun.
72
534-544
2016
Escherichia coli (P76461)
Zhou, P.; Zhu, Z.; Hidayatullah Khan, M.; Zheng, P.; Teng, M.; Niu, L.
Crystal structure of cytoplasmic acetoacetyl-CoA thiolase from Saccharomyces cerevisiae
Acta Crystallogr. F Struct. Biol. Commun.
74
6-13
2018
Saccharomyces cerevisiae (P41338), Saccharomyces cerevisiae
Zhang, Y.; Wei, W.; Fan, J.; Jin, C.; Lu, L.; Fang, W.
Aspergillus fumigatus mitochondrial acetyl coenzyme A acetyltransferase as an antifungal target
Appl. Environ. Microbiol.
86
e02986
2020
Aspergillus fumigatus (B0XMC1), Aspergillus fumigatus, Aspergillus fumigatus CEA10 (B0XMC1)
Jeon, J.M.; Kim, H.J.; Bhatia, S.K.; Sung, C.; Seo, H.M.; Kim, J.H.; Park, H.Y.; Lee, D.; Brigham, C.J.; Yang, Y.H.
Application of acetyl-CoA acetyltransferase (AtoAD) in Escherichia coli to increase 3-hydroxyvalerate fraction in poly(3-hydroxybutyrate-co-3-hydroxyvalerate)
Bioprocess Biosyst. Eng.
40
781-789
2017
Escherichia coli (P76461), Escherichia coli
Wang, M.; Wang, D.; Zhang, Q.; Chai, J.; Peng, Y.; Cai, X.
Identification and cytochemical immunolocalization of acetyl-CoA acetyltransferase involved in the terpenoid mevalonate pathway in Euphorbia helioscopia laticifers
Bot. Stud.
58
62
2017
Euphorbia helioscopia (A0A0M4F9H9), Euphorbia helioscopia
Chen, Q.; Yan, J.; Meng, X.; Xu, F.; Zhang, W.; Liao, Y.; Qu, J.
Molecular cloning, characterization, and functional analysis of acetyl-CoA C-acetyltransferase and mevalonate kinase genes involved in terpene trilactone biosynthesis from Ginkgo biloba
Molecules
22
74
2017
Ginkgo biloba (A0A1S6KJS1), Ginkgo biloba
Nakao, N.; Kaneda, H.; Tsushima, N.; Tanaka, M.
Characterization of primary structure and post-hatching increase in chicken cytosolic acetoacetyl-coA thiolase in the liver
Poult. Sci.
95
1406-1410
2016
Gallus gallus (F1NT20), Gallus gallus
Voegeli, B.; Engilberge, S.; Girard, E.; Riobe, F.; Maury, O.; Erb, T.J.; Shima, S.; Wagner, T.
Archaeal acetoacetyl-CoA thiolase/HMG-CoA synthase complex channels the intermediate via a fused CoA-binding site
Proc. Natl. Acad. Sci. USA
115
3380-3385
2018
Methanothermococcus thermolithotrophicus, Methanothermococcus thermolithotrophicus (A0A384E138), Methanothermococcus thermolithotrophicus DSM 2095, Methanothermococcus thermolithotrophicus DSM 2095 (A0A384E138)
Wang, X.; Wang, S.; Xu, X.; Sun, J.; Ma, Y.; Liu, Z.; Sun, T.; Zou, L.
Molecular cloning, characterization, and heterologous expression of an acetyl-CoA acetyl transferase gene from Sanghuangporus baumii
Protein Expr. Purif.
170
105592
2020
Sanghuangporus baumii
Srirangan, K.; Liu, X.; Tran, T.T.; Charles, T.C.; Moo-Young, M.; Chou, C.P.
Engineering of Escherichia coli for direct and modulated biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) copolymer using unrelated carbon sources
Sci. Rep.
6
36470
2016
Cupriavidus necator (P14611), Cupriavidus necator ATCC 17699 (P14611)
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