2.3.1.94: 6-deoxyerythronolide-B synthase
This is an abbreviated version!
For detailed information about 6-deoxyerythronolide-B synthase, go to the full flat file.
Word Map on EC 2.3.1.94
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2.3.1.94
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synthases
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aspergillus
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nonribosomal
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ketosynthase
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macrolide
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acyltransferase
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starter
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iterative
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thioesterase
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ketoreductase
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actinomycete
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melanin
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coelicolor
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erythraea
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mycotoxin
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saccharopolyspora
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macrolactone
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macrocyclic
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polyene
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actinorhodin
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beta-ketoacyl
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ochratoxin
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citrinin
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monascus
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enoyl
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deoxysugars
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multimodular
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fujikuroi
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hygroscopicus
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myxobacterium
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verticillioides
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avermitilis
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avermectins
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phosphopantetheinylated
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macrolactams
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pyrone
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16-membered
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phosphopantetheine
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rifamycins
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bimodular
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epothilone
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nrpss
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halogenase
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ansamycins
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synthesis
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ochraceus
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pptases
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antibioticus
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biotechnology
-
enediyne
-
meroterpenoids
-
analysis
-
4'-phosphopantetheine
- 2.3.1.94
- synthases
- aspergillus
-
nonribosomal
-
ketosynthase
-
macrolide
- acyltransferase
-
starter
-
iterative
-
thioesterase
- ketoreductase
-
actinomycete
- melanin
- coelicolor
- erythraea
-
mycotoxin
- saccharopolyspora
-
macrolactone
-
macrocyclic
-
polyene
-
actinorhodin
-
beta-ketoacyl
-
ochratoxin
- citrinin
- monascus
-
enoyl
-
deoxysugars
-
multimodular
- fujikuroi
- hygroscopicus
-
myxobacterium
- verticillioides
- avermitilis
- avermectins
-
phosphopantetheinylated
-
macrolactams
-
pyrone
-
16-membered
- phosphopantetheine
- rifamycins
-
bimodular
-
epothilone
-
nrpss
- halogenase
-
ansamycins
- synthesis
- ochraceus
- pptases
- antibioticus
- biotechnology
-
enediyne
-
meroterpenoids
- analysis
- 4'-phosphopantetheine
Reaction
Synonyms
6-deoxyerythronolide B, 6-deoxyerythronolide B synthase, DEBS, DEBS1, DEBS2, DEBS3, deoxyerythronolide B synthase, deoxyerythronolide B synthase 1, deoxyerythronolide B synthase 2, deoxyerythronolide B synthase 3, eryA, erythromycin polyketide synthase, erythronolide condensing enzyme, erythronolide synthase, PKS, polyketide synthase, synthase, erythronolide
ECTree
2.3.1.94 6-deoxyerythronolide-B synthaseAdvanced search results
results (
results (Inhibitors
Inhibitors on EC 2.3.1.94 - 6-deoxyerythronolide-B synthase
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INHIBITOR 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
(3R,5R)-diphenyl 6-(3,5-dihydroxy-6-phenylhexanoylamino)hexylphosphonate
phosphonate ester, close structural homolog of substrates known to undergo macrocyclization and hydrolysis. The ester effectively inhibits the enzyme, but does not lead to co-complex structures. Pretreatment of recombinant thioesterase, residues15-283, with inhibitor for 18 h abolishes enzymatic activity for hydrolysis of the N-acetyl-cysteamine thioester of 3-hydroxyheptanoate
(3S,5R)-diphenyl 6-(3,5-dihydroxy-6-phenylhexanoylamino)hexylphosphonate
phosphonate ester, close structural homolog of substrates known to undergo macrocyclization and hydrolysis. The ester effectively inhibits the enzyme, but does not lead to co-complex structures. Pretreatment of recombinant thioesterase, residues15-283, with inhibitor for 18 h abolishes enzymatic activity for hydrolysis of the N-acetyl-cysteamine thioester of 3-hydroxyheptanoate
