2.3.1.B16: taxoid C-13 O-phenylpropanoyltransferase

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For detailed information about taxoid C-13 O-phenylpropanoyltransferase, go to the full flat file.

Reaction

Synonyms

baccatin III 13-O-(3-amino-3-phenylpropanoyl)transferase, TAX7

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.B16 taxoid C-13 O-phenylpropanoyltransferase

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Results	in table
1	AA Sequence
1	Cloned(Commentary)
2	KM Value [mM]
2	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
1	Organism
2	Pathway
1	pH Optimum
1	Purification (Commentary)
1	Reaction
1	Reference
3	Substrates and Products (Substrate)
2	Subunits
2	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Substrates Products

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Substrates Products on EC 2.3.1.B16 - taxoid C-13 O-phenylpropanoyltransferase

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baccatin III + 3-amino-3-phenylpropanoyl-CoA

3'-N-debenzoyl-2'-deoxytaxol + coenzyme A

2 entries

baccatin III + 3-phenylisoserinoyl-CoA

? + coenzyme A

Taxus cuspidata

Q8H2B5

selective for 3-amino-3-phenylpropanoyl-CoA esters with a preference for beta-phenylalanoyl-CoA over 3-phenylisoserinoyl-CoA. Activity with 3-phenylisoserinoyl-CoA is 40% of the activity with beta-phenylalanoyl-CoA. alpha-Phenylalanoyl-CoA and N-benzoyl phenylisoserinoyl-CoA are not productive acyl donors

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