2.3.1.B25: octaketide synthase
This is an abbreviated version!
For detailed information about octaketide synthase, go to the full flat file.
Word Map on EC 2.3.1.B25
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2.3.1.B25
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plant-specific
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aloe
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arborescens
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condensations
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pentaketide
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chromone
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anthraquinone
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dynemicins
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micromonospora
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10-membered
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benzophenone
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calicheamicin
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hexaketide
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precursor-directed
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anthrone
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naphthopyrone
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benzalacetone
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nonaketide
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n-methylanthraniloyl-coa
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acridone
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spring-8
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palmatum
-
tetraketides
-
neocarzinostatin
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synthesis
-
molecular biology
- 2.3.1.B25
-
plant-specific
- aloe
- arborescens
-
condensations
-
pentaketide
- chromone
- anthraquinone
- dynemicins
- micromonospora
-
10-membered
- benzophenone
-
calicheamicin
-
hexaketide
-
precursor-directed
- anthrone
-
naphthopyrone
- benzalacetone
-
nonaketide
- n-methylanthraniloyl-coa
-
acridone
-
spring-8
- palmatum
-
tetraketides
-
neocarzinostatin
- synthesis
- molecular biology
Reaction
16 malonyl-CoA + 28 H+ = 16 CoA + + + 16 CO2 + 16 H2O
Synonyms
AaOKS, DynE8, enediyne PKS, enediyne polyketide synthase, OKS, oktaketide synthase, PksE, plant type III OKS, plant type III polyketide synthase
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Reference
Reference on EC 2.3.1.B25 - octaketide synthase
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Abe, I.
Engineering of plant polyketide biosynthesis
Chem. Pharm. Bull.
56
1505-1514
2008
Aloe arborescens (Q3L7F5)
Watanabe, K.; Praseuth, A.P.; Wang, C.C.
A comprehensive and engaging overview of the type III family of polyketide synthases
Curr. Opin. Chem. Biol.
11
279-286
2007
Aloe arborescens (Q3L7F5)
Lee, Y.S.; Ju, H.K.; Kim, Y.J.; Lim, T.G.; Uddin, M.R.; Kim, Y.B.; Baek, J.H.; Kwon, S.W.; Lee, K.W.; Seo, H.S.; Park, S.U.; Yang, T.J.
Enhancement of anti-inflammatory activity of Aloe vera adventitious root extracts through the alteration of primary and secondary metabolites via salicylic acid elicitation
PLoS ONE
8
e82479
2013
Aloe vera
Andersen-Ranberg, J.; Kongstad, K.T.; Nafisi, M.; Staerk, D.; Okkels, F.T.; Mortensen, U.H.; Lindberg Moeller, B.; Frandsen, R.J.N.; Kannangara, R.
Synthesis of C-glucosylated octaketide anthraquinones in Nicotiana benthamiana by using a multispecies-based biosynthetic pathway
ChemBioChem
18
1893-1897
2017
Aloe arborescens (Q3L7F5)
Cohen, D.; Townsend, C.
A dual role for a polyketide synthase in dynemicin enediyne and anthraquinone biosynthesis
Nat. Chem.
10
231-236
2018
Micromonospora chersina (Q84HI8), Micromonospora chersina, Micromonospora chersina NRRL B-24756 (Q84HI8)
Frandsen, R.J.N.; Khorsand-Jamal, P.; Kongstad, K.T.; Nafisi, M.; Kannangara, R.M.; Staerk, D.; Okkels, F.T.; Binderup, K.; Madsen, B.; Moller, B.L.; Thrane, U.; Mortensen, U.H.
Heterologous production of the widely used natural food colorant carminic acid in Aspergillus nidulans
Sci. Rep.
8
12853
2018
Aloe arborescens (Q3L7F5)
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