Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.3.1.B34: [protein]-L-lysine N-acetyltransferase

This is an abbreviated version!
For detailed information about [protein]-L-lysine N-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.B34

Reaction

acetyl-CoA
+
[an AMP-forming acyl-CoA synthase]-L-lysine
=
CoA
+
[an AMP-forming acyl-CoA synthase]-N6-acetyl-L-lysine

Synonyms

acetoin utilization protein, acetyltransferase Pat, AcuA, ArtC, BsAcuA, epsilonN-lysine acetyltransferase, GCN5-related N-acetyltransferase, KAT, Micau_1670, MSMEG_5458, Mxan_3215, Pat, PatA, peptidyl-lysine N-acetyltransferase, protein acetyltransferase, Rv0998, SaAcuA, SACE_5148, SePat, SSPG_01886, type-I bGNAT, type-IV bGNAT, YhiQ

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.B34 [protein]-L-lysine N-acetyltransferase

Natural Substrates Products

Natural Substrates Products on EC 2.3.1.B34 - [protein]-L-lysine N-acetyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
acetyl-CoA + [AacS]-L-Lys617
CoA + [AacS]-Nepsilon-acetyl-L-Lys617
show the reaction diagram
acetyl-CoA + [AceA]-L-Lys
CoA + [AceA]-N6-acetyl-L-Lys
show the reaction diagram
acetyl-CoA + [AceK]-L-Lys
CoA + [AceK]-N6-acetyl-L-Lys
show the reaction diagram
acetyl-CoA + [AcsA]-L-Lys
CoA + [AcsA]-N6-acetyl-L-Lys
show the reaction diagram
acetyl-CoA + [ACS]-L-Lys
CoA + [ACS]-N6-acetyl-L-Lys
show the reaction diagram
acetyl-CoA + [BsAcsA]-L-Lys
CoA + [BsAcsA]-N6-acetyl-L-Lys
show the reaction diagram
acetyl-CoA + [BtyA]-L-Lys
CoA + [BtyA]-N6-acetyl-L-Lys
show the reaction diagram
-
substrate is a AMP-forming acyl-CoA synthase, acetylation occurs at the catalytic lysine residue
-
-
?
acetyl-CoA + [DcaA]-L-Lys
CoA + [DcaA]-N6-acetyl-L-Lys
show the reaction diagram
-
substrate is a AMP-forming acyl-CoA synthase, acetylation occurs at the catalytic lysine residue
-
-
?
acetyl-CoA + [DcaB]-L-Lys
CoA + [DcaB]-N6-acetyl-L-Lys
show the reaction diagram
-
substrate is a AMP-forming acyl-CoA synthase, acetylation occurs at the catalytic lysine residue
-
-
?
acetyl-CoA + [DcaC]-L-Lys
CoA + [DcaC]-N6-acetyl-L-Lys
show the reaction diagram
-
substrate is a AMP-forming acyl-CoA synthase, acetylation occurs at the catalytic lysine residue
-
-
?
acetyl-CoA + [LcsB mutant L500V]-L-Lys
CoA + [LcsB mutant L500V]-N6-acetyl-L-Lys
show the reaction diagram
-
wild-type AMP-forming acyl-CoA synthase LcsB is not a substrate, acetylation of mutant L500V occurs at the catalytic lysine residue
-
-
?
acetyl-CoA + [Micau_0428]-L-Lys619
CoA + [Micau_0428]-N6-acetyl-L-Lys619
show the reaction diagram
acetyl-CoA + [PimA]-L-Lys534
CoA + [PimA]-N6-acetyl-L-Lys534
show the reaction diagram
-
substrate is a AMP-forming acyl-CoA synthase
alanine substitutions at residues Pro528, Arg529, Thr530, Val532, and Gly533 of PimA result in variants that are acetylated less than 50% relative to the wild-type protein. C-terminal to the acetylation site, alanine substitutions at residues Arg537, Leu540, and Arg541 yield variants that also showed less than 50% of wild-type acetylation
-
?
acetyl-CoA + [SeAcs]-L-Lys
CoA + [SeAcs]-N6-acetyl-L-Lys
show the reaction diagram
acetyl-CoA + [VcsA]-L-Lys
CoA + [VcsA]-N6-acetyl-L-Lys
show the reaction diagram
-
substrate is a AMP-forming acyl-CoA synthase, acetylation occurs at the catalytic lysine residue
-
-
?
propionyl-CoA + [AcsA]-L-Lys
CoA + [AcsA]-N6-propionyl-L-Lys
show the reaction diagram
AcsA is AMP-forming acetyl-CoA synthetase from Staphylococcus aureus (SaAcs)
-
-
?
propionyl-CoA + [PprE]-L-Lys
CoA + [PprE]-N6-propionyl-L-Lys
show the reaction diagram
PprE is propionyl-CoA synthetase
-
-
?
succinyl-CoA + [AcsA]-L-Lys
CoA + [AcsA]-N6-succinyl-L-Lys
show the reaction diagram
AcsA is AMP-forming acetyl-CoA synthetase from Staphylococcus aureus (SaAcs). AcuA is the first documented case of a bacterial GNAT capable of succinylation
-
-
?
additional information
?
-