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2.3.1.B37: phenylglycine N-acetyltransferase

This is an abbreviated version!
For detailed information about phenylglycine N-acetyltransferase, go to the full flat file.

Reaction

acetyl-CoA
+
L-phenylglycine
=
(2S)-2-acetylamino-2-phenylacetic acid

Synonyms

NatA

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.B37 phenylglycine N-acetyltransferase

Inhibitors

Inhibitors on EC 2.3.1.B37 - phenylglycine N-acetyltransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
4-chloromercuribenzoate
35.2% residual activity after 1 h at 1 mM
AgNO3
22.4% residual activity after 1 h at 1 mM
Cu2+
79.5% residual activity after 1 h at 1 mM
diethyldicarbonate
49.3% residual activity after 1 h at 1 mM
diethylpyrocarbonate
35.2% residual activity after 1 h at 1 mM
Hg2+
19.8% residual activity after 1 h at 1 mM
Mg2+
94.2% residual activity after 1 h at 1 mM
N-ethylmaleimide
34.5% residual activity after 1 h at 1 mM
o-phenanthroline
93.1% residual activity after 1 h at 1 mM
additional information
Mn2+, EDTA, tiron, alpha,alpha'-dipyridyl, phenylglyoxal, phenylmethylsulfonyl fluoride, iodoacetic acid and iodoacetamide do not markedly inhibit the enzyme
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