2.3.1.B38: heptylquinolone synthase

This is an abbreviated version!
For detailed information about heptylquinolone synthase, go to the full flat file.

Word Map on EC 2.3.1.B38

2.3.1.B38

aeruginosa

opportunistic

condensing

n-oxides

2-heptyl-3-hydroxy-41h-quinolone

heterodimeric

Reaction

Synonyms

2-heptyl-4(1H)-quinolone synthase, PqsB, PqsBC, PqsC

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.B38 heptylquinolone synthase

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Results	in table
1	AA Sequence
1	Cloned(Commentary)
1	Crystallization (Commentary)
18	General Information
5	Inhibitors
1	Ki Value [mM]
2	KM Value [mM]
10	Natural Substrates/ Products (Substrates)
11	Organism
10	Protein Variants
1	Reaction
11	Reference
10	Substrates and Products (Substrate)
37	Synonyms
1	Systematic Name
1	Turnover Number [1/s]

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Reference on EC 2.3.1.B38 - heptylquinolone synthase

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735925

Dulcey, C.E.; Dekimpe, V.; Fauvelle, D.A.; Milot, S.; Groleau, M.C.; Doucet, N.; Rahme, L.G.; Lepine, F.; Deziel, E.

The end of an old hypothesis: the Pseudomonas signaling molecules 4-hydroxy-2-alkylquinolines derive from fatty acids, not 3-ketofatty acids

Chem. Biol.

1481-1491

2013

Pseudomonas aeruginosa (A0A0H2Z7A3 and A0A0H2Z7K6), Pseudomonas aeruginosa UCBPP-PA14 (A0A0H2Z7A3 and A0A0H2Z7K6)

24239007

736509

Drees, S.L.; Li, C.; Prasetya, F.; Saleem, M.; Dreveny, I.; Williams, P.; Hennecke, U.; Emsley, J.; Fetzner, S.

PqsBC, a condensing enzyme in the biosynthesis of the Pseudomonas aeruginosa quinolone signal: crystal structure, inhibition, and reaction mechanism

J. Biol. Chem.

291

6610-6624

2016

Pseudomonas aeruginosa (Q9I4X1)

26811339

756793

Allegretta, G.; Maurer, C.; Eberhard, J.; Maura, D.; Hartmann, R.; Rahme, L.; Empting, M.

In-depth profiling of MvfR-regulated small molecules in Pseudomonas aeruginosa after Quorum Sensing inhibitor treatment

Front. Microbiol.

924

2017

Pseudomonas aeruginosa (Q9I4X1 AND Q9I4X2), Pseudomonas aeruginosa ATCC 15692 (Q9I4X1 AND Q9I4X2), Pseudomonas aeruginosa 1C (Q9I4X1 AND Q9I4X2), Pseudomonas aeruginosa PRS 101 (Q9I4X1 AND Q9I4X2), Pseudomonas aeruginosa DSM 22644 (Q9I4X1 AND Q9I4X2), Pseudomonas aeruginosa CIP 104116 (Q9I4X1 AND Q9I4X2), Pseudomonas aeruginosa LMG 12228 (Q9I4X1 AND Q9I4X2), Pseudomonas aeruginosa JCM 14847 (Q9I4X1 AND Q9I4X2)

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