2.3.1.B39: brefelding octaketide synthase
This is an abbreviated version!
For detailed information about brefelding octaketide synthase, go to the full flat file.
Word Map on EC 2.3.1.B39
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2.3.1.B39
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synthases
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iterative
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starter
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tetraketide
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enoyl
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phytotoxic
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megasynthase
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resorcylic
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polyene
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terreus
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diketide
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squalestatin
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n-acetylcysteamine
- 2.3.1.B39
- synthases
-
iterative
-
starter
-
tetraketide
-
enoyl
-
phytotoxic
-
megasynthase
-
resorcylic
-
polyene
- terreus
-
diketide
- squalestatin
- n-acetylcysteamine
Reaction
Synonyms
Bref-PKS, highly reducing polyketide synthase, HRPKS
ECTree
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General Information
General Information on EC 2.3.1.B39 - brefelding octaketide synthase
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physiological function
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enzyme is involved in biosynthesis of brefeldin A. It synthesizes the precisely reduced oktaketide precursor, which can then be directly offloaded by the thiohydrolase enzyme followed by a P450-mediated formation of the cyclopentane ring and macrocyclization to afford 7-deoxy brefeldin A.thiolase Bref-TH controls the programmed release of the oktaketide product from synthase Bref-PKS
physiological function
-
enzyme is involved in biosynthesis of brefeldin A. It synthesizes the precisely reduced oktaketide precursor, which can then be directly offloaded by the thiohydrolase enzyme followed by a P450-mediated formation of the cyclopentane ring and macrocyclization to afford 7-deoxy brefeldin A.thiolase Bref-TH controls the programmed release of the oktaketide product from synthase Bref-PKS
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