Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.3.2.13: protein-glutamine gamma-glutamyltransferase

This is an abbreviated version!
For detailed information about protein-glutamine gamma-glutamyltransferase, go to the full flat file.

Word Map on EC 2.3.2.13

Reaction

protein glutamine
+
alkylamine
=
protein N5-alkylglutamine
 +
NH3

Synonyms

AcTG-1, BmTGA, chloroplast transglutaminase, chlTGase, cold active transglutaminase, cold-active transglutaminase, EPB42, factor XIII, factor XIIIa, fibrin stabilizing factor, fibrinoligase, Galphah, glutamine:amine gamma-glutamyl-transferase, glutaminylpeptide gamma-glutamyltransferase, glutamyltransferase, glutaminylpeptide gamma-, gpTGase 2, gTG2, hfXIIIa, hTG2, hTGase 1, hTGase 2, hTGase 3, hTGase 6, KALB, KalbTG, KALB_7456, Laki-Lorand factor, mammalian transglutaminase, microbial transglutaminase, microbial transglutaminases, MsTGase, MTG, MTG-TX, MTGase, mTGase 2, OlTGT, plastidial transglutaminase, polyamine transglutaminase, protein 4.2, protein-glutamine gamma-glutamyltransferase, R-glutaminyl-peptide:amine gamma-glutamyl transferase, R-glutaminylpeptide-amine gamma-glutamyltransferase, SCTG, SMTG, STG I, t-TG, TG-2, TG1, TG2, TG3, TG4, TG5, TG6, TG7, tGA, TGase, TGase 1, TGase 2, Tgase 3, TGase 6, Tgase II, TGase-2, TGase2, TGB, TGK1, TGK2, TGL, TGM1, TGM2, TGM3, TGM4, TGM5, TGM6, TGM7, TGZ, tgz15, TGZo, tissue transglutaminase, tissue transglutaminase 2, tissue-TG, transglutaminase, transglutaminase 1, transglutaminase 2, transglutaminase 3, transglutaminase 6, transglutaminase C, transglutaminase factor XIII, transglutaminase type II, transglutaminase-2, transglutaminase-like protein, transglutaminase2, tTG, tTG-2, type 2 transglutaminase, type I transglutaminase, type-2 transglutaminase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.2 Aminoacyltransferases
                2.3.2.13 protein-glutamine gamma-glutamyltransferase

Molecular Weight

Molecular Weight on EC 2.3.2.13 - protein-glutamine gamma-glutamyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
100000
101000
-
gel filtration
104000
x * 104000, GST and PreScission Protease-tagged enzyme, estimated from SDS-PAGE
160000
-
gel filtration
170000 - 180000
gel filtration
27000
-
2 * 27000, hair follicle transglutaminase, SDS-PAGE
28000
-
x * 82000, full length protein, x * 53000 + x * 28000, proteolytically processed N-terminal active fragment and C-terminal regulatory domain, respectively
280000 - 330000
-
plasma factor XIII, gel filtration and sedimentation equilibrium
29000
-
x * 29000, brain transglutaminse NII, SDS-PAGE
33000
-
1 * 33000
38000
-
x * 38000, SDS-PAGE
39000
-
x * 39000, SDS-PAGE
39198
-
x * 39198, mass spectrometry
39200
-
x * 39200, calculated from amino acid sequence
39500
-
gel filtration
39600
-
2 * 39600, SDS-PAGE
40000
42500
43600
x * 43600, pro-enzyme, calculated from amino acid sequence
45000
47000
-
x * 47000, fusion protein with N-terminal His-tag
50000
-
epidermal and hair follicle cationic isozyme, gel filtration
53000
-
x * 82000, full length protein, x * 53000 + x * 28000, proteolytically processed N-terminal active fragment and C-terminal regulatory domain, respectively
54000
-
hair follicle transglutaminase, gel filtration
55000
58000
-
x * 58000, SDS-PAGE
61000
-
x * 61000 Da, SDS-PAGE, immunoblot
65000
70000
-
x * 70000, partially purified enzyme, SDS-PAGE
71000
-
alpha2beta2, 4 * 71000, plasma factor XIIIa, alpha is the proteolytically modified catalytic subunit of factor XIII, SDS-PAGE
73183
-
x * 73183, factor XIII beta-subunit, deduced from nucleotide sequence
75000
76000
-
x * 76000, SDS-PAGE
76620
-
1 * 76620, liver transglutaminase, deduced from nucleotide sequence
76900
-
sedimentation and diffusion
77000
77600
78000
78520
-
1 * 78520, including the C-terminal His-tag and GTP, calculated from amino acid sequence
78570
-
1 * 78570, multiangle light scattering
80240
recombinant His-tagged enzyme mutant G224V with bound GTP, gel filtration
82000
83005
83010
-
primary structure
84000
-
x * 84000, recombinant transglutaminase 5, immunoblot
84280
2 * 84280, MALDI-TOF, 2 * 85000-90000, SDS-PAGE
84713
-
x * 84713, deduced from gene sequence
85000
86000
-
1 * 86000, SDS-PAGE
86000 - 94000
-
sedimentation equilibrium
88000
-
tissue transglutaminase, gel filtration
89000
-
x * 89000, SDS-PAGE
90000
92000
-
1 * 92000, SDS-PAGE with or without 2-mercaptoethanol
94000
-
x * 94000, SDS-PAGE
95000
96000
-
1 * 96000, gel filtration in the presence of 1 mM Ca2+
additional information
-
TG2 can assume multiple conformations