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2.3.2.15: glutathione gamma-glutamylcysteinyltransferase

This is an abbreviated version!
For detailed information about glutathione gamma-glutamylcysteinyltransferase, go to the full flat file.

Word Map on EC 2.3.2.15

Reaction

glutathione
+
[Glu(-Cys)]n-Gly
=
Gly
+
[Glu(-Cys)]n+1-Gly

Synonyms

AdPCS1, AdPCS2, AdPCS3, alr0975, AtPCS, AtPCS1, AtPCS2, AtPCSI, BjPCS1, CaPCS1, CaPCS2, CePCS, DaPCS1, gamma-EC dipeptidyl(trans)peptidase, gamma-glutamyl-cysteine transpeptidase, gamma-glutamylcysteine dipeptidyl transpeptidase, gamma-glutamylcysteine transpeptidase, gamma-glutamylcysteinyl dipeptidyl transpeptidase, gamma-glutamylcysteinyl transpeptidase, glutathione gamma-glutamylcysteinyltransferase, LjPCS1, LjPCS3, MnPCS1, MnPCS2, NsPCS, OsPCS1, OsPCS15, OsPCS1a, OsPCS1b, OsPCS1c, OsPCS1full, OsPCS2, OsPCS5, PC synthase, PCS, PCS1, PCS15, PCS2, PCS5, phytochelatin synthase, phytochelatin synthase 1, phytochelatin synthase 2, phytochelatin synthase1, pPhytochelatin synthase, pseudo-phytochelatin synthase, SrPCS, SrPCS1, SrPCS2, SrPCS3, SrPCS4, TtpsiPCS

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.2 Aminoacyltransferases
                2.3.2.15 glutathione gamma-glutamylcysteinyltransferase

Activating Compound

Activating Compound on EC 2.3.2.15 - glutathione gamma-glutamylcysteinyltransferase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
As3+
70fold activation at 0.05 mM, recombinant MBP-tagged isozyme PCS1
GSH
-
the maximal activity is attained at GSH concentrations around 10 and 15 mM when the enzyme is assayed in the presence of 0.005 and 0.01 mM total Cd2+, respectively
additional information
-