2.3.2.2: gamma-glutamyltransferase

This is an abbreviated version!
For detailed information about gamma-glutamyltransferase, go to the full flat file.

Reaction

Synonyms

(5-L-glutamyl) peptide: amino-acid 5-glutamyl transferase, alpha-glutamyl transpeptidase, AngammaGT, AsGGT1, At1g69820, At4g29210, At4g39640, At4g39650, BaGGT, BaGGT42, BaGGT469, BlGGT, BlGGT13, BsGGT168, Cgl0954, eqGGT, gamma glutamyl transferase, gamma-glutamyl peptidyltransferase, gamma-glutamyl transferase, gamma-glutamyl transferase 1, gamma-glutamyl transferase 5, gamma-glutamyl transferase/transpeptidase, gamma-glutamyl transferases, gamma-glutamyl transpeptidase, gamma-glutamyl transpeptidase 1, gamma-glutamyl transpeptidase 4, gamma-glutamyl transpeptidase-1, gamma-glutamyl-transpeptidase, gamma-glutamyltransferase, gamma-glutamyltranspeptidase, gamma-GPT, gamma-GT, gamma-GTase, gamma-GTP, gammaGT, GGT, GGT A, GGT I, GGT-1, GGT1, GGT2, GGT3, GGT4, GGT5, ggtB, GGTII protein, GGTLA1, glutamyl transpeptidase, glutamyltransferase, gamma-, HGGT, L-gamma-glutamyl transpeptidase, L-gamma-glutamyltransferase, L-glutamyltransferase, More, PnGGT, SBLGGT, VvGGT3

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.2 Aminoacyltransferases

                2.3.2.2 gamma-glutamyltransferase

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Results	in table
53	Activating Compound
36225	AA Sequence
60	Application
1	CAS Registry Number
48	Cloned(Commentary)
8	Crystallization (Commentary)
16191	Disease/ Diagnostics
6	Expression
90	General Information
8	General Stability
452	Inhibitors
23	kcat/KM [mM/s]
78	Ki Value [mM]
222	KM Value [mM]
150	Localization
64	Metals/Ions
190	Molecular Weight [Da]
120	Natural Substrates/ Products (Substrates)
1068	Organism
10	Pathway
105	PDB ID
113	pH Optimum
34	pH Range
14	pH Stability
1	pI Value
85	Posttranslational Modification
113	Protein Variants
105	Purification (Commentary)
49	Reaction
1	Reaction Type
314	Reference
5	Renatured (Commentary)
329	Source Tissue
109	Specific Activity [micromol/min/mg]
17	Storage Stability
1121	Substrates and Products (Substrate)
119	Subunits
317	Synonyms
1	Systematic Name
82	Temperature Optimum [°C]
16	Temperature Range [°C]
37	Temperature Stability [°C]
43	Turnover Number [1/s]

General Stability

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of the Enzyme Summary Page.

General Stability on EC 2.3.2.2 - gamma-glutamyltransferase

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GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

dilution inactivates

Morchella esculenta

-

487951

freezing or lyophilization inactivates purified enzyme

Phaseolus vulgaris

-

487954

GdnHCl-induced denaturation of BlGGT and its variants, overview

Bacillus licheniformis

Q62WE3

756966

glycerol, 5% v/v, stabilizes

Morchella esculenta

-

487951

PMSF stabilizes

Homo sapiens

-

487903

the enzyme is highly salt-tolerant, at pH 5.5 in presence of 18% NaCl, 49% of the transpeptidation activity and 86% of the hydrolysis activity remains, conversion of Gln to Glu shows 76% residual activity

Bacillus subtilis

-

658567

the enzyme retains 86% of its activity even in 3 M NaCl

Bacillus subtilis

P54422

719449

transpeptidase activity is salt-sensitive

Bacillus licheniformis

-

707820