2.3.2.26: HECT-type E3 ubiquitin transferase

This is an abbreviated version, for detailed information about HECT-type E3 ubiquitin transferase, go to the full flat file.

Reaction

S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine
+
[acceptor protein]-L-lysine
=
[E2 ubiquitin-conjugating enzyme]-L-cysteine
+
N6-ubiquitinyl-[acceptor protein]-L-lysine

Synonyms

AIP2, AIP4, atrophin-1 interacting protein 2, E3 ligase, E3 ubiquitin-protein ligase NEDD4, E6-AP, E6AP, ETC-1, HECT domain E3 ubiquitin ligase, HECT ligase, HECT-domain ubiquitin ligase, HECT-type E3 ligase, HECT-type ubiquitin E3 ligase, HECTD3, HECTWWP2, Herc4, Itch, Nedd4, Nedd4 HECT, Nedd4-1, Nedd4L, NEDL1, NleL, RSP5, Smurf1, TRIP12, Ube3C, UBR1, UBR5, UPL3, UPL5, WW domain-containing E3 Ub–protein ligase 2, WWP1, WWP2

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.2 Aminoacyltransferases
                2.3.2.26 HECT-type E3 ubiquitin transferase