2.3.2.8: arginyltransferase

This is an abbreviated version!
For detailed information about arginyltransferase, go to the full flat file.

Reaction

Synonyms

Arg-transferase, Arg-tRNA transferase, Arg-tRNA-protein transferase, Arg-tRNA-proteintransferase, arginyl transferase, arginyl tRNA transferase, arginyl-transfer ribonucleate-protein aminoacyltransferase, arginyl-transfer ribonucleate-protein transferase, arginyl-transferase, arginyl-tRNA protein transferase, arginyl-tRNA--protein transferase, arginyl-tRNA--protein transferase 1, arginyl-tRNA-protein transferase, arginyl-tRNA-protein transferase 1, arginyl-tRNA:protein arginyltransferase, arginyltransferase, arginyltransferase 1, ATE, Ate1, ATE1-1, ATE1-2, Ate1-3, Ate1-4, ATE1-encoded R-transferase, DdAte1, L-arginyltransferase, R-transferase

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.2 Aminoacyltransferases

                2.3.2.8 arginyltransferase

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Results	in table
5	Activating Compound
4154	AA Sequence
3	Application
1	CAS Registry Number
23	Cloned(Commentary)
1	Cofactor
40	Disease/ Diagnostics
9	Expression
93	General Information
5	General Stability
4	IC50 Value
37	Inhibitors
4	Ki Value [mM]
2	KM Value [mM]
28	Localization
7	Metals/Ions
7	Molecular Weight [Da]
71	Natural Substrates/ Products (Substrates)
188	Organism
1	Pathway
18	PDB ID
3	pH Optimum
2	pH Range
18	Protein Variants
11	Purification (Commentary)
1	Reaction
9	Reaction Type
64	Reference
74	Source Tissue
8	Specific Activity [micromol/min/mg]
6	Storage Stability
153	Substrates and Products (Substrate)
15	Subunits
111	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Turnover Number [1/s]

Disease

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Disease on EC 2.3.2.8 - arginyltransferase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Breast Neoplasms

Inhibition of arginyltransferase 1 induces transcriptional activity of myocardin-related transcription factor A (MRTF-A) and promotes directional migration.

25381249

Carcinogenesis

MTrasT24, a metallothionein-ras fusion gene, modulates expression in cultured rat liver cells of two genes associated with in vivo liver cancer.

2893374

Cardiomegaly

Arginyltransferase knockdown attenuates cardiac hypertrophy and fibrosis through TAK1-JNK1/2 pathway.

31953451

Cardiomegaly

Author Correction: Arginyltransferase knockdown attenuates cardiac hypertrophy and fibrosis through TAK1-JNK1/2 pathway.

32581244

Cardiomyopathy, Dilated

Contractility of myofibrils from the heart and diaphragm muscles measured with atomic force cantilevers: Effects of heart-specific deletion of arginyl-tRNA-protein transferase.

23739549

Heart Failure

Contractility of myofibrils from the heart and diaphragm muscles measured with atomic force cantilevers: Effects of heart-specific deletion of arginyl-tRNA-protein transferase.

23739549

Leukemia

Slow reacting substances (leukotrienes): enzymes involved in their biosynthesis.

6126878

Neoplasm Metastasis

Arginyltransferase suppresses cell tumorigenic potential and inversely correlates with metastases in human cancers.

26686093

Neoplasm Metastasis

ATE1 Inhibits Liver Cancer Progression through RGS5-Mediated Suppression of Wnt/?-Catenin Signaling.

34158395

Neoplasm Metastasis

Reduced Arginyltransferase 1 is a driver and a potential prognostic indicator of prostate cancer metastasis.

30177837

Neoplasms

Arginyltransferase suppresses cell tumorigenic potential and inversely correlates with metastases in human cancers.

26686093

Neoplasms

ATE1 Inhibits Liver Cancer Progression through RGS5-Mediated Suppression of Wnt/?-Catenin Signaling.

34158395

Neoplasms

Comment on "Multiple logistic regression analysis predicts cancer risk among tobacco usage with glutathione R-transferase p1 genotyping in patients with head and neck cancer".

32594073

Neoplasms

Multiple competing RNA structures dynamically control alternative splicing in the human ATE1 gene.

33330934

Prostatic Neoplasms

Reduced Arginyltransferase 1 is a driver and a potential prognostic indicator of prostate cancer metastasis.

30177837

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