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BRENDA support

2.3.2.B1: lipid II:alanine alanyl transferase

This is an abbreviated version!
For detailed information about lipid II:alanine alanyl transferase, go to the full flat file.

Reaction

UDP-MurNAc-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine
+
L-alanyl-tRNA
=
UDP-MurNAc-L-alanyl-gamma-D-glutamyl-L-lysyl(N6-L-alanyl)-D-alanyl-D-alanine
+
tRNA

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.2 Aminoacyltransferases
                2.3.2.B1 lipid II:alanine alanyl transferase

Reference

Reference on EC 2.3.2.B1 - lipid II:alanine alanyl transferase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Cressina, E.; Lloyd, A.J.; De Pascale, G.; Mok, B.J.; Caddick, S.; Roper, D.I.; Dowson, C.G.; Bugg, T.D.H.
Inhibition of tRNA-dependent ligase MurM from Streptococcus pneumoniae by phosphonate and sulfonamide inhibitors
Bioorg. Med. Chem.
17
3443-3455
2009
Streptococcus pneumoniae
Manually annotated by BRENDA team
Filipe, s.R.; Pinho, M.G.; Tomasz, A.
Characterization of the murMN operon involved in the synthesis of branched peptidoglycan peptides in Streptococcus pneumoniae
J. Biol. Chem.
275
27768-27774
2000
Streptococcus pneumoniae (Q9K307), Streptococcus pneumoniae (Q9L447), Streptococcus pneumoniae R36A (Q9L447), Streptococcus pneumoniae Pen6 (Q9K307)
Manually annotated by BRENDA team
Filipe, S.R.; Severina, E.; Tomasz, A.
Functional analysis of Streptococcus pneumoniae MurM reveals the region responsible for its specificity in the synthesis of branched cell wall peptides
J. Biol. Chem.
276
39618-39628
2001
Streptococcus pneumoniae (Q9L447)
Manually annotated by BRENDA team
Lloyd, A.J.; Gilbey, A.M.; Blewett, A.M.; De Pascale, G.; El Zoeiby, A.; Levesque, R.C.; Catherwood, A.C.; Tomasz, A.; Bugg, T.D.H.; Roper, D.I.; Dowson, C.G.
Characterization of tRNA-dependent peptide bond formation by MurM in the synthesis of Streptococcus pneumoniae peptidoglycan
J. Biol. Chem.
283
6402-6417
2008
Streptococcus pneumoniae, Streptococcus pneumoniae 159, Streptococcus pneumoniae Pn16
Manually annotated by BRENDA team