Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.4.1.102: beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

This is an abbreviated version!
For detailed information about beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase, go to the full flat file.

Word Map on EC 2.4.1.102

Reaction

UDP-N-acetyl-alpha-D-glucosamine
+
O3-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl/threonyl-[protein]
=
UDP
+
O3-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl/threonyl-[protein]

Synonyms

2beta-1,6-acetylglucosaminyltransferase, acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-mucin beta-(1-6)-, acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-mucin beta-(1-6)-, A, bC2GnT-M, beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3, beta-1,6-N-acetylglucosaminyltransferase, beta1,6-N-acetylglucosaminyltransferase, beta6-N-acetylglucosaminyltransferase, Bo17, C2 beta6GnT1, C2/4GnT, C24GNT, C2GlcNAcT-I, C2GlcNAcT-II, C2GlcNAcT-III, C2GnT, C2GnT-1, C2GnT-I, C2GnT-L, c2GnT-M, C2GnT1, C2GnT2, C2GnT3, C2GNTM, C4GnT, core 2 acetylglucosaminyltransferase, core 2 beta-1, 6-N-acetylglucosaminyltransferase-1, core 2 beta-1,6 N-acetylglucosaminyltransferase, core 2 beta-1,6-N-acetylglucosaminyltransferase, core 2 beta1,6 N-acetylglucosaminyltransferase, core 2 beta1,6 N-acetylglucosaminyltransferase-I, core 2 beta1,6-N-acetyl-glycosaminyltransferase, core 2 beta1,6-N-acetylglucosaminyl transferase 1, core 2 beta1,6-N-acetylglucosaminyltransferase, core 2 beta1,6-N-acetylglucosaminyltransferase I, core 2 beta1,6-N-acetylglucosaminyltransferase-I, core 2 beta6-GlcNAc-transferase, core 2 beta6-N-acetylglucosaminyltransferase, core 2 GlcNAc-T, core 2 N-acetylglucosaminyltransferase, Core 2 N-acetylglucosaminyltransferase 2/M, core 2 N-acetylglucosaminyltransferase M, core 2 N-acetylglucosaminyltransferase-1, core 2 N-acetylglucosaminyltransferase-M, core 2 protein beta-1,6-N-acetylglucosaminyltransferase-mucin type, core 2beta 1,6 N-acetylglucosaminyltransferase, core 2beta-1,6-acetylglucosaminyltransferase, core 6-beta-GlcNAc-T, core 6-beta-GlcNAc-transferase A, core2 1-6-N-glucosaminyltransferase-I, core2 beta(1,6)-N-acetyglucosaminyltransferase-I, core2 beta-1,6-N-acetylglucosaminyltransferase, core2 beta-1,6-N-acetylglucosaminyltransferase-1, Core2beta1,6GnT type M, core2GnT, GCNT1, gcnt3, gcnt4, GnT-III, GNTM, More, mucin-type core 2 1,6-N-acetylglucosaminyltransferase enzyme, mucus-type core 2 beta1,6 N-acetylglucosaminyltransferase, O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I, uridine diphosphoacetylglucosamine-mucin beta-(1-6)-acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-mucin beta-(1-6)-acetylglucosaminyltransferase A

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.102 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

Reference

Reference on EC 2.4.1.102 - beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Schachter, H.; Brockhausen, I.; Hull, E.
High-performance liquid chromatography assays for N-acetylglucosaminyltransferases involved in N- and O-glycan synthesis
Methods Enzymol.
179
351-397
1989
Bos taurus, Canis lupus familiaris, Oryctolagus cuniculus, Ovis aries, Homo sapiens, Platyrrhini, Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
Mendicino, J.; Sangadala, S.
Purification and characterization of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase from swine trachea epithelium
Mol. Cell. Biochem.
185
135-145
1998
Sus scrofa
Manually annotated by BRENDA team
Oehrlein, R.; Hindsgaul, O.; Palcic, M.M.
Use of the core-2-N-acetylglucosaminyltransferase in the chemical-enzymic synthesis of a sialyl-LeX-containing hexasaccharide found on O-linked glycoproteins
Carbohydr. Res.
244
149-159
1993
Mus musculus
Manually annotated by BRENDA team
Higgins, E.A.; Siminovitch, K.A.; Zhuang, D.; Brockhausen, I.; Dennis, J.W.
Aberrant O-linked oligosaccharide biosynthesis in lymphocytes and platelets from patients with the Wiskott-Aldrich syndrome
J. Biol. Chem.
266
6280-6290
1991
Homo sapiens
Manually annotated by BRENDA team
Kuhns, W.; Rutz, V.; Paulsen, H.; Matta, K.L.; Baker, M.A.; Barner, M.; Granovsky, M.; Brockhausen, I.
Processing O-glycan core 1, Galb1-3GalNAca-R. Specificities of core 2, UDP-GlcNAc: Galbeta1-3GalNAc-R(GlcNAc to GalNAc) beta6-N-acetylglucosaminyltransferase and CMP-sialic acid: Galbeta1-3GalNAc-R alpha3-sialyltransferase
Glycoconjugate J.
10
381-394
1993
Gallus gallus, Homo sapiens, Mus musculus, Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
Brockhausen, I.; Rachaman, E.S.; Matta, K.L.; Schachter, H.
The separation by liquid chromatography (under elevated pressure) of phenyl, benzyl, and O-nitrophenyl glycosides of oligosaccharides. Analysis of substrates and products for four N-acetyl-D-glucosaminyl-transferases involved in mucin synthesis
Carbohydr. Res.
120
3-16
1983
Canis lupus familiaris, Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
Brockhausen, I.; Matta, K.L.; Orr, J.; Schachter, H.
Mucin synthesis. UDP-GlcNAc:GalNAc-R beta 3-N-acetylglucosaminyltransferase and UDP-GlcNAc:GlcNAc beta 1-3GalNAc-R (GlcNAc to GalNAc) beta 6-N-acetylglucosaminyltransferase from pig and rat colon mucosa
Biochemistry
24
1866-1874
1985
Canis lupus familiaris, Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
Vavasseur, F.; Yang, J.M.; Dole, K.; Paulsen, H.; Brockhausen, I.
Synthesis of O-glycan core 3: characterization of UDP-GlcNAc:GalNAc-R beta3-N-acetyl-glucosaminyltransferase activity from colonic mucosal tissues and lack of the activity in human cancer cell lines
Glycobiology
5
351-357
1995
Homo sapiens
Manually annotated by BRENDA team
Williams, D.; Schachter, H.
Mucin synthesis. I. Detection in canine submaxillary glands of an N-acetylglucosaminyltransferase which acts on mucin substrates
J. Biol. Chem.
255
11247-11252
1980
Canis lupus familiaris
Manually annotated by BRENDA team
Williams, D.; Longmore, G.; Matta, K.L.; Schachter, H.
Mucin synthesis. II. Substrate specificity and product identification studies on canine submaxillary gland UDP-GlcNAc:Gal beta 1-3GalNAc(GlcNAc leads to GalNAc) beta 6-N-acetylglucosaminyltransferase
J. Biol. Chem.
255
11253-11261
1980
Canis lupus familiaris
Manually annotated by BRENDA team
Datti, A.; Dennis, J.W.
Regulation of UDP-GlcNAc:Galbeta1-3GalNAc-R beta1-6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc) in chinese hamster ovary cells
J. Biol. Chem.
268
5409-5416
1993
Cricetulus griseus
Manually annotated by BRENDA team
Toki, D.; Granovsky, M.A.; Reck, F.; Kuhns, W.; Baker, M.A.; Matta, K.L.; Brockhausen, I.
Inhibition of UDP-GlcNAc:Gal beta 1-3GalNAc-R (GlcNAc to GalNAc) beta 6-N-acetylglucosaminyltransferase from acute myeloid leukaemia cells by photoreactive nitrophenyl substrate derivatives
Biochem. Biophys. Res. Commun.
198
417-423
1994
Homo sapiens, Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
Zeng, S.; Dinter, A.; Eisenkratzer, D.; Biselli, M.; Wandrey, C.; Berger, E.G.
Pilot scale expression and purification of soluble protein A tagged beta1,6N-acetylglucosaminyltransferase in CHO cells
Biochem. Biophys. Res. Commun.
237
653-658
1997
Mus musculus
Manually annotated by BRENDA team
Toki, D.; Sarkar, M.; Yip, B.; Reck, F.; Joziasse, D.; Fukuda, M.; Schachter, H.; Brockhausen, I.
Expression of stable human O-glycan core 2 beta-1,6-N-acetylglycosaminyltransferase in Sf9 insect cells
Biochem. J.
325
63-69
1997
Homo sapiens
-
Manually annotated by BRENDA team
Nakamura, M.; Kudo, T.; Narimatsu, H.; Furukawa, Y.; Kikuchi, J.; Asakura, S.; Yang, W.; Iwase, S.; Hatake, K.; Miura, Y.
Single glycosyltransferase, core 2 beta1-6-N-acetylglucosaminyltransferase, regulates cell surface sialyl-Lex expression level in human pre-B lymphocytic leukemia cell line KM3 treated with phorbolester
J. Biol. Chem.
273
26779-26789
1998
Homo sapiens
Manually annotated by BRENDA team
Beum, P.V.; Singh, J.; Burdick, M.; Hollingsworth, M.A.; Cheng, P.W.
Expression of core 2 beta-1,6-N-acetylglucosaminyltransferase in a human pancreatic cancer cell line results in altered expression of MUC1 tumor-associated epitopes
J. Biol. Chem.
274
24641-24648
1999
Homo sapiens
Manually annotated by BRENDA team
Schwientek, T.; Yeh, J.C.; Levery, S.B.; Keck, B.; Merkx, G.; Van Kessel, A.G.; Fukuda, M.; Clausen, H.
Control of O-glycan branch formation: molecular cloning and characterization of a novel thymus-associated core 2 beta1,6-N-acetylglucosaminyltransferase
J. Biol. Chem.
275
11106-11113
2000
Homo sapiens (O95395), Homo sapiens (Q02742), Homo sapiens (Q9P109), Homo sapiens
Manually annotated by BRENDA team
Koya, D.; Dennis, J.W.; Warren, C.E.; Takahara, N.; Schoen, F.J.; Nishio, Y.; Nakajima, T.; Lipes, M.A.; King, G.L.
Overexpression of core 2 N-acetylglycosaminyltransferase enhances cytokine actions and induces hypertrophic myocardium in transgenic mice
FASEB J.
13
2329-2337
1999
Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Vanderplasschen, A.; Markine-Goriaynoff, N.; Lomonte, P.; Suzuki, M.; Hiraoka, N.; Yeh, J.C.; Bureau, F.; Willems, L.; Thiry, E.; Fukuda, M.; Pastoret, P.P.
A multipotential beta-1,6-N-acetylglucosaminyltransferase is encoded by bovine herpesvirus type 4
Proc. Natl. Acad. Sci. USA
97
5756-5761
2000
Bovine gammaherpesvirus 4 (Q9IZK2), Bovine gammaherpesvirus 4
Manually annotated by BRENDA team
Lim, Y.C.; Xie, H.; Come, C.E.; Alexander, S.I.; Grusby, M.J.; Lichtman, A.H.; Luscinskas, F.W.
IL-12, STAT4-dependent up-regulation of CD4+ T cell core 2 beta-1,6-n-acetylglucosaminyltransferase, an enzyme essential for biosynthesis of P-selectin ligands
J. Immunol.
167
4476-4484
2001
Mus musculus
Manually annotated by BRENDA team
Brockhausen, I.; Kuhns, W.; Schachter, H.; Matta K.L.; Sutherland, D.R.; Baker, M.A.
Biosynthesis of O-glycans in leukocytes from normal donors and from patients with leukemia: increase in O-glycan core 2 UDP-GlcNAc:Galbeta3GalNAcalpha-R (GlcNAc to GalNAc) beta(1,6)-N-acetylglucosaminyltransferase in leikemic cells
Cancer Res.
51
1257-1263
1991
Homo sapiens
Manually annotated by BRENDA team
Brockhausen, I.; Romero, P.A.; Herscovics, A.
Glycosyltransferase changes upon differentiation of CaCo-2 human colonic adenocarcinoma cells
Cancer Res.
51
3136-3142
1991
Homo sapiens
Manually annotated by BRENDA team
Beum, P.V.; Basma, H.; Bastola, D.R.; Cheng, P.W.
Mucin biosynthesis: upregulation of core 2 beta 1,6 N-acetylglucosaminyltransferase by retinoic acid and Th2 cytokines in a human airway epithelial cell line
Am. J. Physiol.
288
L116-124
2005
Homo sapiens
Manually annotated by BRENDA team
Yang, X.; Qin, W.; Lehotay, M.; Toki, D.; Dennis, P.; Schutzbach, J.S.; Brockhausen, I.
Soluble human core 2 beta6-N-acetylglucosaminyltransferase C2GnT1 requires its conserved cysteine residues for full activity
Biochim. Biophys. Acta
1648
62-74
2003
Homo sapiens
Manually annotated by BRENDA team
Yen, T.Y.; Macher, B.A.; Bryson, S.; Chang, X.; Tvaroska, I.; Tse, R.; Takeshita, S.; Lew, A.M.; Datti, A.
Highly conserved cysteines of mouse core 2 beta1,6-N-acetylglucosaminyltransferase I form a network of disulfide bonds and include a thiol that affects enzyme activity
J. Biol. Chem.
278
45864-45881
2003
Mus musculus
Manually annotated by BRENDA team
Singh, J.; Khan, G.A.; Kinarsky, L.; Cheng, H.; Wilken, J.; Choi, K.H.; Bedows, E.; Sherman, S.; Cheng, P.W.
Identification of disulfide bonds among the nine core 2 N-acetylglucosaminyltransferase-M cysteines conserved in the mucin beta6-N-acetylglucosaminyltransferase family
J. Biol. Chem.
279
38969-38977
2004
Bos taurus
Manually annotated by BRENDA team
Merzaban, J.S.; Zuccolo, J.; Corbel, S.Y.; Williams, M.J.; Ziltener, H.J.
An alternate core 2 beta1,6-N-acetylglucosaminyltransferase selectively contributes to P-selectin ligand formation in activated CD8 T cells
J. Immunol.
174
4051-4059
2005
Mus musculus
Manually annotated by BRENDA team
Prorok-Hamon, M.; Notel, F.; Mathieu, S.; Langlet, C.; Fukuda, M.; El-Battari, A.
N-glycans of core2 beta(1,6)-N-acetylglucosaminyltransferase-I (C2GnT-I) but not those of alpha(1,3)-fucosyltransferase-VII (FucT-VII) are required for the synthesis of functional P-selectin glycoprotein ligand-1 (PSGL-1): effects on P-, L- and E-selectin
Biochem. J.
391
491-502
2005
Homo sapiens
Manually annotated by BRENDA team
Cabrera, P.V.; Amano, M.; Mitoma, J.; Chan, J.; Said, J.; Fukuda, M.; Baum, L.G.
Haploinsufficiency of C2GnT-I glycosyltransferase renders T lymphoma cells resistant to cell death
Blood
108
2399-2406
2006
Mus musculus
Manually annotated by BRENDA team
Ben-Mahmud, B.M.; Chan, W.H.; Abdulahad, R.M.; Datti, A.; Orlacchio, A.; Kohner, E.M.; Chibber, R.
Clinical validation of a link between TNF-alpha and the glycosylation enzyme core 2 GlcNAc-T and the relationship of this link to diabetic retinopathy
Diabetologia
49
2185-2191
2006
Homo sapiens
Manually annotated by BRENDA team
Hagisawa, S.; Ohyama, C.; Takahashi, T.; Endoh, M.; Moriya, T.; Nakayama, J.; Arai, Y.; Fukuda, M.
Expression of core 2 beta1,6-N-acetylglucosaminyltransferase facilitates prostate cancer progression
Glycobiology
15
1016-1024
2005
Homo sapiens
Manually annotated by BRENDA team
Falkenberg, V.R.; Fregien, N.
Control of core 2 beta1,6 N-acetylglucosaminyltransferase-I transcription by Sp1 in lymphocytes and epithelial cells
Glycoconj. J.
24
511-519
2007
Homo sapiens
Manually annotated by BRENDA team
Pak, J.E.; Arnoux, P.; Zhou, S.; Sivarajah, P.; Satkunarajah, M.; Xing, X.; Rini, J.M.
X-ray crystal structure of leukocyte type core 2 beta1,6-N-acetylglucosaminyltransferase. Evidence for a convergence of metal ion-independent glycosyltransferase mechanism
J. Biol. Chem.
281
26693-26701
2006
Mus musculus
Manually annotated by BRENDA team
Kikuchi, J.; Ozaki, H.; Nonomura, C.; Shinohara, H.; Iguchi, S.; Nojiri, H.; Hamada, H.; Kiuchi, A.; Nakamura, M.
Transfection of antisense core 2 beta1,6-N-acetylglucosaminyltransferase-1 cDNA suppresses selectin ligand expression and tissue infiltration of B-cell precursor leukemia cells
Leukemia
19
1934-1940
2005
Homo sapiens
Manually annotated by BRENDA team
Radhakrishnan, P.; Beum, P.V.; Tan, S.; Cheng, P.W.
Butyrate induces sLex synthesis by stimulation of selective glycosyltransferase genes
Biochem. Biophys. Res. Commun.
359
457-462
2007
Bos taurus
Manually annotated by BRENDA team
Valenzuela, H.F.; Pace, K.E.; Cabrera, P.V.; White, R.; Porvari, K.; Kaija, H.; Vihko, P.; Baum, L.G.
O-glycosylation regulates LNCaP prostate cancer cell susceptibility to apoptosis induced by galectin-1
Cancer Res.
67
6155-6162
2007
Homo sapiens
Manually annotated by BRENDA team
Hashimoto, M.; Tan, S.; Mori, N.; Cheng, H.; Cheng, P.W.
Mucin biosynthesis: molecular cloning and expression of mouse mucus-type core 2 beta1,6 N-acetylglucosaminyltransferase
Glycobiology
17
994-1006
2007
Mus musculus (Q5JCT0), Mus musculus
Manually annotated by BRENDA team
Julien, S.; Grimshaw, M.J.; Sutton-Smith, M.; Coleman, J.; Morris, H.R.; Dell, A.; Taylor-Papadimitriou, J.; Burchell, J.M.
Sialyl-Lewis(x) on P-selectin glycoprotein ligand-1 is regulated during differentiation and maturation of dendritic cells: a mechanism involving the glycosyltransferases C2GnT1 and ST3Gal I
J. Immunol.
179
5701-5710
2007
Homo sapiens
Manually annotated by BRENDA team
Wang, H.; Tang, R.; Zhang, W.; Amirikian, K.; Geng, Z.; Geng, J.; Hebbel, R.P.; Xia, L.; Marth, J.D.; Fukuda, M.; Katoh, S.; Huo, Y.
Core2 1-6-N-glucosaminyltransferase-I is crucial for the formation of atherosclerotic lesions in apolipoprotein E-deficient mice
Arterioscler. Thromb. Vasc. Biol.
29
180-187
2009
Mus musculus
Manually annotated by BRENDA team
Brockhausen, I.; Dowler, T.; Paulsen, H.
Site directed processing: role of amino acid sequences and glycosylation of acceptor glycopeptides in the assembly of extended mucin type O-glycan core 2
Biochim. Biophys. Acta
1790
1244-1257
2009
Homo sapiens
Manually annotated by BRENDA team
Hatakeyama, S.; Kyan, A.; Yamamoto, H.; Okamoto, A.; Sugiyama, N.; Suzuki, Y.; Yoneyama, T.; Hashimoto, Y.; Koie, T.; Yamada, S.; Saito, H.; Arai, Y.; Fukuda, M.; Ohyama, C.
Core 2 N-acetylglucosaminyltransferase-1 expression induces aggressive potential of testicular germ cell tumor
Int. J. Cancer
127
10521-10529
2010
Homo sapiens
Manually annotated by BRENDA team
Wang, J.; Shiratori, I.; Satoh, T.; Lanier, L.L.; Arase, H.
An essential role of sialylated O-linked sugar chains in the recognition of mouse CD99 by paired Ig-like type 2 receptor (PILR)
J. Immunol.
180
1686-1693
2008
Mus musculus (Q09324), Mus musculus
Manually annotated by BRENDA team
Stone, E.L.; Ismail, M.N.; Lee, S.H.; Luu, Y.; Ramirez, K.; Haslam, S.M.; Ho, S.B.; Dell, A.; Fukuda, M.; Marth, J.D.
Glycosyltransferase function in core 2-type protein O glycosylation
Mol. Cell. Biol.
29
3770-3782
2009
Mus musculus, Mus musculus (Q5JCT0)
Manually annotated by BRENDA team
Nagaraj, S.; Neumann, J.; Winzen, B.; Frank, S.; Ziske, C.; Sievers, E.; Koch, N.; Schmidt-Wolf, I.G.
Pancreas carcinoma antigen fused to invariant chain elicits T-cell response and tumor growth inhibition
Pancreas
37
321-327
2008
Mus musculus
Manually annotated by BRENDA team
Schroeter, M.F.; Ratsch, B.A.; Lehmann, J.; Baumgrass, R.; Hamann, A.; Syrbe, U.
Differential regulation and impact of fucosyltransferase VII and core 2 beta1,6-N-acetyl-glycosaminyltransferase for generation of E- and P-selectin ligands in murine CD4+ T cells
Immunology
137
294-304
2012
Mus musculus
Manually annotated by BRENDA team
Pak, J.E.; Satkunarajah, M.; Seetharaman, J.; Rini, J.M.
Structural and mechanistic characterization of leukocyte-type core 2 ?1,6-N-acetylglucosaminyltransferase: a metal-ion-independent GT-A glycosyltransferase
J. Mol. Biol.
414
798-811
2011
Mus musculus (Q09324)
Manually annotated by BRENDA team
Sato, T.; Yoneyama, T.; Tobisawa, Y.; Hatakeyama, S.; Yamamoto, H.; Kojima, Y.; Mikami, J.; Mori, K.; Hashimoto, Y.; Koie, T.; Ohyama, C.
Core 2 beta-1, 6-N-acetylglucosaminyltransferase-1 expression in prostate biopsy specimen is an indicator of prostate cancer aggressiveness
Biochem. Biophys. Res. Commun.
470
150-156
2016
Homo sapiens (Q02742), Homo sapiens
Manually annotated by BRENDA team
Rao, C.; Janakiram, N.; Madka, V.; Kumar, G.; Scott, E.; Pathuri, G.; Bryant, T.; Kutche, H.; Zhang, Y.; Biddick, L.; Gali, H.; Zhao, Y.; Lightfoot, S.; Mohammed, A.
Small-molecule inhibition of GCNT3 disrupts mucin biosynthesis and malignant cellular behaviors in pancreatic cancer
Cancer Res.
76
1965-1974
2016
Homo sapiens (O95395), Homo sapiens, Mus musculus (Q5JCT0), Mus musculus, Mus musculus C57BL/6 (Q5JCT0)
Manually annotated by BRENDA team
Tvaroska, I.; Kozmon, S.; Wimmerova, M.; Koca, J.
A QM/MM investigation of the catalytic mechanism of metal-ion-independent core 2 beta1,6-N-acetylglucosaminyltransferase
Chemistry
19
8153-8162
2013
Mus musculus (Q09324)
Manually annotated by BRENDA team
Gonzalez-Vallinas, M.; Vargas, T.; Moreno-Rubio, J.; Molina, S.; Herranz, J.; Cejas, P.; Burgos, E.; Aguayo, C.; Custodio, A.; Reglero, G.; Feliu, J.; Ramirez de Molina, A.
Clinical relevance of the differential expression of the glycosyltransferase gene GCNT3 in colon cancer
Eur. J. Cancer
51
1-8
2015
Homo sapiens (O95395), Homo sapiens
Manually annotated by BRENDA team
Miyamoto, T.; Suzuki, A.; Asaka, R.; Ishikawa, K.; Yamada, Y.; Kobara, H.; Nakayama, J.; Shiozawa, T.
Immunohistochemical expression of core 2 beta1,6-N-acetylglucosaminyl transferase 1 (C2GnT1) in endometrioid-type endometrial carcinoma: a novel potential prognostic factor
Histopathology
62
986-993
2013
Homo sapiens
Manually annotated by BRENDA team
Petrosyan, A.; Ali, M.F.; Cheng, P.W.
Keratin 1 plays a critical role in Golgi localization of core 2 N-acetylglucosaminyltransferase M via interaction with its cytoplasmic tail
J. Biol. Chem.
290
6256-6269
2015
Homo sapiens (O95395), Homo sapiens
Manually annotated by BRENDA team
Liu, J.; Jin, C.; Cherian, R.M.; Karlsson, N.G.; Holgersson, J.
O-glycan repertoires on a mucin-type reporter protein expressed in CHO cell pools transiently transfected with O-glycan core enzyme cDNAs
J. Biotechnol.
199
77-89
2015
Homo sapiens (Q02742)
Manually annotated by BRENDA team
Lete, C.; Markine-Goriaynoff, N.; Machiels, B.; Pang, P.C.; Xiao, X.; Canis, K.; Suzuki, M.; Fukuda, M.; Dell, A.; Haslam, S.M.; Vanderplasschen, A.; Gillet, L.
Bovine herpesvirus 4 modulates its beta-1,6-N-acetylglucosaminyltransferase activity through alternative splicing
J. Virol.
90
2039-2051
2015
Bovine gammaherpesvirus 4 (Q9IZK2), Bovine gammaherpesvirus 4 V. test (Q9IZK2)
Manually annotated by BRENDA team
Kojima, Y.; Yoneyama, T.; Hatakeyama, S.; Mikami, J.; Sato, T.; Mori, K.; Hashimoto, Y.; Koie, T.; Ohyama, C.; Fukuda, M.; Tobisawa, Y.
Detection of core2 beta-1,6-N-acetylglucosaminyltransferase in post-digital rectal examination urine is a reliable indicator for extracapsular extension of prostate cancer
PLoS ONE
10
e0138520
2015
Homo sapiens
Manually annotated by BRENDA team
Tseng, T.H.; Lin, T.W.; Chen, C.Y.; Chen, C.H.; Lin, J.L.; Hsu, T.L.; Wong, C.H.
Substrate preference and interplay of fucosyltransferase 8 and N-acetylglucosaminyltransferases
J. Am. Chem. Soc.
139
9431-9434
2017
Homo sapiens (O95395)
Manually annotated by BRENDA team
Lete, C.; Markine-Goriaynoff, N.; Machiels, B.; Pang, P.; Xiao, X.; Canis, K.; Suzuki, M.; Fukuda, M.; Dell, A.; Haslam, S.; Vanderplasschen, A.; Gillet, L.
Bovine herpesvirus 4 modulates its beta-1,6-n-acetylglucosaminyltransferase activity through alternative splicing
J. Virol.
90
2039-2051
2016
Bovine gammaherpesvirus 4
Manually annotated by BRENDA team
Mardahl, M.; Schroeter, M.F.; Engelbert, D.; Pink, M.; Sperandio, M.; Hamann, A.; Syrbe, U.
Core 2 beta1,6-N-acetylglucosaminyltransferase-I, crucial for P-selectin ligand expression is controlled by a distal enhancer regulated by STAT4 and T-bet in CD4+ T helper cells 1
Mol. Immunol.
77
132-140
2016
Homo sapiens (Q02742)
Manually annotated by BRENDA team
Sumardika, I.W.; Youyi, C.; Kondo, E.; Inoue, Y.; Ruma, I.M.W.; Murata, H.; Kinoshita, R.; Yamamoto, K.I.; Tomida, S.; Shien, K.; Sato, H.; Yamauchi, A.; Futami, J.; Putranto, E.W.; Hibino, T.; Toyooka, S.; Nishibori, M.; Sakaguchi, M.
beta-1,3-Galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 increases MCAM stability, which enhances S100A8/A9-mediated cancer motility
Oncol. Res.
26
431-444
2018
Homo sapiens (O95395), Homo sapiens
Manually annotated by BRENDA team
Fernandez, L.P.; Sanchez-Martinez, R.; Vargas, T.; Herranz, J.; Martin-Hernandez, R.; Mendiola, M.; Hardisson, D.; Reglero, G.; Feliu, J.; Redondo, A.; Ramirez de Molina, A.
The role of glycosyltransferase enzyme GCNT3 in colon and ovarian cancer prognosis and chemoresistance
Sci. Rep.
8
8485
2018
Homo sapiens (O95395), Homo sapiens
Manually annotated by BRENDA team
Liu, J.; Zhang, Y.; Liu, W.; Zhang, Q.; Xiao, H.; Song, H.; Luo, B.
MiR-BART1-5p targets core 2beta-1,6-acetylglucosaminyltransferase GCNT3 to inhibit cell proliferation and migration in EBV-associated gastric cancer
Virology
541
63-74
2020
Homo sapiens (O95395), Homo sapiens
Manually annotated by BRENDA team