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2.4.1.11: glycogen(starch) synthase

This is an abbreviated version!
For detailed information about glycogen(starch) synthase, go to the full flat file.

Word Map on EC 2.4.1.11

Reaction

UDP-alpha-D-glucose
+
[(1->4)-alpha-D-glucosyl]n
=
UDP
+
[(1->4)-alpha-D-glucosyl]n+1

Synonyms

Cg-GYS, GBSS, GBSSI, glucosyltransferase, uridine diphosphoglucose-glycogen, glycogen synthase, glycogen synthase 2, glycogen synthase-2, glycogen synthetase (starch), granule bound starch synthase, granule-bound starch synthase, GS-I, GSN, GSY2p, Gys-2, GYS1, GYS2, Gys2p, starch synthase I, starch/glycogen synthase, TVAG_258220, UDP-glucose-glycogen glucosyltransferase, UDP-glycogen synthase, UDPG-glycogen synthetase, UDPG-glycogen transglucosylase, uridine diphosphoglucose-glycogen glucosyltransferase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.11 glycogen(starch) synthase

General Stability

General Stability on EC 2.4.1.11 - glycogen(starch) synthase

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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
albumin is essential during lyophilization, lyophilized enzyme is stable for years
-
dithiothreitol stabilizes
-
freezing leads to loss of activity
-
glucose 6-phosphate stabilizes
-
glycogen stabilizes
Li+ increases hepatic glycogen synthase stability though a proteasome-related mechanism
-
phosphate stabilizes
-
spontaneous, temperature-dependent inactivation caused by irreversible conformational changes
-
sulfate stabilizes
UDP stabilizes
-
UDP-glucose stabilizes
-