2.4.1.143: alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

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For detailed information about alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, go to the full flat file.

Reaction

Synonyms

2-beta-N-acetylglucosaminyltransferase, acetylglucosaminyltransferase II, alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase, alpha-1,6-mannosylglycoprotein beta-1-2-N-acetylglucosaminyltransferase, beta-1,2-N-acetylglucosaminyltransferase II, BmGnTII, EC 2.4.1.51, GlcNAc-T II, GlcNAcT-II, GlcNAcTase-II, GnT II, Gnt II-A, Gnt II-B, GnT-II, GnTII, Mgat2, N-acetylglucosaminyltransferase II, N-acetylglucosaminyltransferase-II, N-acetylglucosaminyltransferases II, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II, TbGnTII, TbGT15, TTV/DEXT1, UDP-GlcNAc:alpha6-D-mannoside beta1,2-N-acetylglucosaminyltransferase II, UDP-GlcNAc:mannoside alpha1-6 acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-alpha-1,6-mannosylglycoprotein beta-1-2-N-acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-alpha-D-mannoside beta1-2-acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-mannoside alpha1->6-acetylglucosaminyltransferase

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.1 Hexosyltransferases

                2.4.1.143 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

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Results	in table
4	Activating Compound
2043	AA Sequence
1	Application
4	CAS Registry Number
14	Cloned(Commentary)
1	Crystallization (Commentary)
34	Disease/ Diagnostics
1	Expression
20	General Information
3	General Stability
17	Inhibitors
16	kcat/KM [mM/s]
5	Ki Value [mM]
35	KM Value [mM]
21	Localization
14	Metals/Ions
8	Molecular Weight [Da]
12	Natural Substrates/ Products (Substrates)
49	Organism
5	Pathway
6	PDB ID
10	pH Optimum
1	pH Range
3	Posttranslational Modification
13	Protein Variants
9	Purification (Commentary)
1	Reaction
1	Reaction Type
47	Reference
57	Source Tissue
6	Specific Activity [micromol/min/mg]
3	Storage Stability
66	Substrates and Products (Substrate)
7	Subunits
54	Synonyms
1	Systematic Name
12	Temperature Optimum [°C]
1	Temperature Stability [°C]
16	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 2.4.1.143 - alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

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MOLECULAR WEIGHT

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

42000

Rattus norvegicus

-

x * 42000, SDS-PAGE

644884, 644885

43000

Rattus norvegicus

-

x * 43000, x * 48000, SDS-PAGE, one or both of these bands represent the enzyme

644865

48000

Rattus norvegicus

-

x * 43000, x * 48000, SDS-PAGE, one or both of these bands represent the enzyme

644865

51100

Sus scrofa

-

calculated from nucleotide sequence

644883

52000

Homo sapiens

-

SDS-PAGE

688325

56000

Homo sapiens

-

gel filtration, fusion protein

644876

additional information

Rattus norvegicus

-

rat enzyme in crude extract exists in 2 forms, high-molecular weight form: above MW 200000, low-molecular weight form: MW 43000-48000, gel filtration

644865