2.4.1.145: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
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For detailed information about alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase, go to the full flat file.
Word Map on EC 2.4.1.145
Reaction
Synonyms
(GnT)-IVa, (GnT)-IVb, alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase, alpha1,3-mannosyl-beta1,4-N-acetylglucosaminyltransferase IV, beta-acetylglucosaminyltransferase IV, EC 2.4.1.51, GlcNAcTase-IV, GnT IV, GnT-IV, GnT-IVa, GnT-IVb, GnTIVa, Mgat4a, Mgat4b, N-acetylglucosaminyltransferase IV, N-acetylglucosaminyltransferase IVa, N-acetylglucosaminyltransferase-IV, N-acetylglucosaminyltransferase-IVa, N-acetylglucosaminyltransferase-IVb, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV, uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase IV
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2.4.1.145 alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferaseAdvanced search results
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Disease on EC 2.4.1.145 - alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
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DISEASE 
TITLE OF PUBLICATION
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alpha-1,3-mannosyl-glycoprotein 4-beta-n-acetylglucosaminyltransferase deficiency
Physiological and glycomic characterization of N-acetylglucosaminyltransferase-IVa and -IVb double deficient mice.
Carcinoma, Hepatocellular
Determination of N-acetylglucosaminyltransferases III, IV and V in normal and hepatoma tissues of rats.
Choriocarcinoma
High expression of N-acetylglucosaminyltransferase IVa promotes invasion of choriocarcinoma.
Choriocarcinoma
Structural differences found in the asparagine-linked sugar chains of human chorionic gonadotropins purified from the urine of patients with invasive mole and with choriocarcinoma.
Choriocarcinoma
Structure, pathology and function of the N-linked sugar chains of human chorionic gonadotropin.
Choriocarcinoma
Unusually high expression of N-acetylglucosaminyltransferase-IVa in human choriocarcinoma cell lines: a possible enzymatic basis of the formation of abnormal biantennary sugar chain.
Diabetes Mellitus, Type 2
Targeted genetic inactivation of N-acetylglucosaminyltransferase-IVa impairs insulin secretion from pancreatic beta cells and evokes type 2 diabetes.
Diabetes Mellitus, Type 2
The transcription of MGAT4A glycosyl transferase is increased in white cells of peripheral blood of Type 2 Diabetes patients.
Hydatidiform Mole, Invasive
N-acetylglucosaminyltransferase IVa promotes invasion of choriocarcinoma.
Lung Neoplasms
Multiplexed surrogate analysis of glycotransferase activity in whole biospecimens.
Neoplasm Metastasis
N-acetylglucosaminyltransferase IVa regulates metastatic potential of mouse hepatocarcinoma cells through glycosylation of CD147.
Neoplasms
Aberrant expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer.
Neoplasms
Glycans and cancer: role of N-glycans in cancer biomarker, progression and metastasis, and therapeutics.
Neoplasms
Identification of hub genes and key pathways associated with the progression of gynecological cancer.
Neoplasms
Kinetic properties and substrate specificities of two recombinant human N-acetylglucosaminyltransferase-IV isozymes.
Neoplasms
Unusually high expression of N-acetylglucosaminyltransferase-IVa in human choriocarcinoma cell lines: a possible enzymatic basis of the formation of abnormal biantennary sugar chain.
Pancreatic Neoplasms
Aberrant expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer.
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