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2.4.1.148: acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

This is an abbreviated version!
For detailed information about acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase, go to the full flat file.

Reaction

UDP-N-acetyl-D-glucosamine
+
N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-D-galactosaminyl-R
=
UDP
+
N-acetyl-beta-D-glucosaminyl-(1->6)-[N-acetyl-beta-D-glucosaminyl-(1->3)]-N-acetyl-D-galactosaminyl-R

Synonyms

acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-mucin beta(1-->6)-, B, bC2GnT-M, C2GnT, C2GnT-2, C2GnT-I, C2GnT-L, c2GnT-M, C2GnT1, C2GnT2, C2GnT3, core 2 beta 1,6 N-acetylglucosaminyltransferase, core 2 beta-1,6-N-acetylglucosaminyltransferase, core 2 beta-1,6-N-acetylglucosaminyltransferase-M, core 2 beta1,6-N-acetylglucosaminyltransferase, core 2 beta6 GlcNAc-transferase, core 2 N-acetylglucosaminyltransferase-M, core 2 _1,6 N-acetylglucosaminyltransferase mucus-type, core 4 beta6-GalNAc-transferase, core 6beta-GalNAc-transferase B, leukocyte-type core 2 beta1,6-N-acetylglucosaminyltransferase, More, mucin-type core 2 beta-1,6-N-acetylglucosaminyltransferase-M, mucin-type core 2 beta-6-GlcNAc-transferase, O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV, uridine diphosphoacetylglucosamine-mucin beta(1-->6)-acetylglucosaminyltransferase B

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.148 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

Crystallization

Crystallization on EC 2.4.1.148 - acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
mutant enzyme C217S in complex with UDP, hanging drop vapor diffusion method, using 24% (w/v) polyethylene glycol 4000, 0.1 M glycine (pH 9.0) and 0.6 M LiCl
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