Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.4.1.15: alpha,alpha-trehalose-phosphate synthase (UDP-forming)

This is an abbreviated version!
For detailed information about alpha,alpha-trehalose-phosphate synthase (UDP-forming), go to the full flat file.

Word Map on EC 2.4.1.15

Reaction

UDP-alpha-D-glucose
+
D-glucose 6-phosphate
=
UDP
+
alpha,alpha-trehalose 6-phosphate

Synonyms

alpha,alpha-trehalose phosphate synthase (UDP-forming), alpha,alpha-trehalose-phosphate synthase (UDP-forming), AtTPS1, AtTPS6, GbTPS, glucosyltransferase, uridine diphosphoglucose phosphate, OtsA, OtsA1, OtsA2, phosphotrehalose-uridine diphosphate transglucosylase, T-6-P, T6P synthase, Ta1210, TPS, TPS-2, TPS-3, TPS1, TPS2, TPS3, TPS5, TPSP, transglucosylase, trehalose 6-phosphate synthase, trehalose 6-phosphate synthase 1, trehalose 6-phosphate synthetase, trehalose phosphate synthase, trehalose phosphate synthase 5, trehalose phosphate synthetase, trehalose phosphate-uridine diphosphate glucosyltransferase, trehalose-6-P synthase, trehalose-6-phosphate synthase, trehalose-6-phosphate synthase 1, trehalose-6-phosphate synthase/phosphatase, trehalose-6P synthase, trehalose-P synthetase, trehalosephosphate-UDP glucosyl transferase, UDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase, UDPglucose-glucose-phosphate glucosyltransferase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.15 alpha,alpha-trehalose-phosphate synthase (UDP-forming)

Engineering

Engineering on EC 2.4.1.15 - alpha,alpha-trehalose-phosphate synthase (UDP-forming)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
D379A
inactive
E387A
inactive
K285A
inactive
E396A
the mutant shows decreased catalytic activity compared to the wild type enzyme
K294A
the mutant shows decreased catalytic activity compared to the wild type enzyme
R22A
the mutant shows decreased catalytic activity compared to the wild type enzyme
R22G
the mutant shows decreased catalytic activity compared to the wild type enzyme
R289A
the mutant shows decreased catalytic activity compared to the wild type enzyme
R327A
the mutant shows decreased catalytic activity compared to the wild type enzyme
W108A
the mutant shows decreased catalytic activity compared to the wild type enzyme
W108S
the mutant shows decreased catalytic activity compared to the wild type enzyme
Y99A
the mutant shows decreased catalytic activity compared to the wild type enzyme
Y99V
the mutant shows decreased catalytic activity compared to the wild type enzyme
D156G
site-directed mutagenesis of a catalytic site residue, catalytically inactive Tps1 mutant variant
H223Y
-
catalytically more active than wild-type enzyme
W111S
site-directed mutagenesis of a catalytic site residue
Y102V
site-directed mutagenesis of a catalytic site residue
additional information